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0000435251
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For application of this approach for the synthesis β-carbonyl phenyl sulfones, see
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79953195452
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If nucleophilic bases, e.g., n -BuLi, are used, the competition between its addition to heterocyclic core of the sulfone and deprotonation of the hydrogen atom α to sulfone is observed.
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If nucleophilic bases, e.g., n -BuLi, are used, the competition between its addition to heterocyclic core of the sulfone and deprotonation of the hydrogen atom α to sulfone is observed.
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23
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0000355152
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79953193007
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See Supporting Information.
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See Supporting Information.
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25
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79953219728
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For discussion about Barbier-type reaction conditions, see Supporting Information.
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For discussion about Barbier-type reaction conditions, see Supporting Information.
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26
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0024801511
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Prepared in situ from the corresponding carboxylic acid
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Prepared in situ from the corresponding carboxylic acid: Ibarra, C. A.; Rodriguez, R. C.; Fernandez Monreal, M. C.; Garcia Navarro, F. J.; Martin Tesorero, J. J. Org. Chem. 1989, 54, 5620
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27
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79953184235
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Coupling between sulfone 13a and BzOMe was extensively studied using various reaction conditions, bases, and solvents. In all cases, only traces of the desired product 11a were observed.
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Coupling between sulfone 13a and BzOMe was extensively studied using various reaction conditions, bases, and solvents. In all cases, only traces of the desired product 11a were observed.
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