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Volumn 76, Issue 7, 2011, Pages 2269-2272

Practical synthesis of β-acyl and β-alkoxycarbonyl heterocyclic sulfones

Author keywords

[No Author keywords available]

Indexed keywords

EFFICIENT SYNTHESIS; STARTING MATERIALS;

EID: 79953199029     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo102326p     Document Type: Article
Times cited : (45)

References (29)
  • 4
    • 79953188995 scopus 로고    scopus 로고
    • special issue on organocatalysis.
    • Chem. Rev. 2007, 107 (12), special issue on organocatalysis.
    • (2007) Chem. Rev. , vol.107 , Issue.12
  • 21
    • 0000435251 scopus 로고
    • For application of this approach for the synthesis β-carbonyl phenyl sulfones, see
    • For application of this approach for the synthesis β-carbonyl phenyl sulfones, see: Bartlett, B. A.; Green, F. R., III; Rose, E. H. J. Am. Chem. Soc. 1978, 100, 4852
    • (1978) J. Am. Chem. Soc. , vol.100 , pp. 4852
    • Bartlett, B.A.1    Green III, F.R.2    Rose, E.H.3
  • 22
    • 79953195452 scopus 로고    scopus 로고
    • If nucleophilic bases, e.g., n -BuLi, are used, the competition between its addition to heterocyclic core of the sulfone and deprotonation of the hydrogen atom α to sulfone is observed.
    • If nucleophilic bases, e.g., n -BuLi, are used, the competition between its addition to heterocyclic core of the sulfone and deprotonation of the hydrogen atom α to sulfone is observed.
  • 24
    • 79953193007 scopus 로고    scopus 로고
    • See Supporting Information.
    • See Supporting Information.
  • 25
    • 79953219728 scopus 로고    scopus 로고
    • For discussion about Barbier-type reaction conditions, see Supporting Information.
    • For discussion about Barbier-type reaction conditions, see Supporting Information.
  • 27
    • 79953184235 scopus 로고    scopus 로고
    • Coupling between sulfone 13a and BzOMe was extensively studied using various reaction conditions, bases, and solvents. In all cases, only traces of the desired product 11a were observed.
    • Coupling between sulfone 13a and BzOMe was extensively studied using various reaction conditions, bases, and solvents. In all cases, only traces of the desired product 11a were observed.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.