Modulating LOV domain photodynamics with a residue alteration outside the chromophore binding site

Biochemistry

Volumn 50, Issue 13, 2011, Pages 2411-2423

  Song, Sang Hun ^a   Freddolino, Peter L ^b,d   Nash, Abigail I ^c   Carroll, Elizabeth C ^a   Schulten, Klaus ^b   Gardner, Kevin H ^c   Larsen, Delmar S ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEINS; AVENA SATIVA; BINDING POCKETS; BIPHASIC; BLUE LIGHT; CYSTEINE RESIDUES; FLAVIN CHROMOPHORES; INTERSYSTEM CROSSING; LIGHT SENSING; LOV DOMAINS; MECHANISTIC MODELS; MOLECULAR DYNAMICS SIMULATIONS; PHOTOCHEMICAL SYSTEMS; PHOTOTROPINS; POINT MUTATIONS; SECOND TIME SCALE; STATE RECOVERY; STRUCTURAL FEATURE; TIME-SCALES; TRANSIENT ABSORPTION; WILD TYPES;

AMINO ACIDS; MOLECULAR DYNAMICS; OXYGEN; PHOTOCHEMICAL FORMING; PROTEINS; TIME MEASUREMENT;

CHROMOPHORES;

AVENA SATIVA PHOTOTROPIN 1; FLAVINE MONONUCLEOTIDE; OXYGEN; PHOTOTROPIN; SOLVENT; UNCLASSIFIED DRUG; VEGETABLE PROTEIN;

ABSORPTION; ARTICLE; BINDING SITE; CHROMATOPHORE; CONTROLLED STUDY; MOLECULAR DYNAMICS; NONHUMAN; PHOTODYNAMICS; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN STRUCTURE; SIMULATION; SPECTROSCOPY; VOLTAGE SENSITIVE DOMAIN;

AMINO ACID SUBSTITUTION; AVENA SATIVA; BINDING SITES; BIOCATALYSIS; FLAVIN MONONUCLEOTIDE; LIGHT; MOLECULAR DYNAMICS SIMULATION; MUTANT PROTEINS; PHOTOTROPINS; POINT MUTATION; PROTEIN STRUCTURE, TERTIARY;

ALGAE; AVENA SATIVA;

EID: 79953191081     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi200198x     Document Type: Article

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