A stereospecific HPLC method and its application in determination of pharmacokinetics profile of two enantiomers of naringenin in rats

Journal of Chromatographic Science

Volumn 49, Issue 4, 2011, Pages 316-320

  Wan, Lili ^a   Sun, Xipeng ^a   Wang, Xiangwei ^b   Liu, Yan ^a   Yu, Qi ^a   Guo, Cheng ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b Medicilon Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RATTUS;

EID: 79953178635     PISSN: 00219665     EISSN: None     Source Type: Journal    
DOI: 10.1093/chrsci/49.4.316     Document Type: Article

References (9)

1. I. Erlund. Review of the flavonoids quercetin, hesperetin, and naringenin. Dietary sources, bioactivities, bioavailability, and epidemiology. Nutr. Res. 24: 851-874 (2004).
2. K.Dastmalchi,H.J.Dorman, P.P.Oinonen, Y.Darwis, I. Laakso, and R. Hiltunen. Chemical composition and in vitro antioxidative activity of a lemon balm (Melissa officinalis L.) extract. LWT 41: 391-400 (2008). (Pubitemid 350160719)
3. H. Doostdar, M.D. Burke, and R.T. Mayer. Bioflavonoids: selective substrates and inhibitors for cytochrome P450 CYP1A and CYP1B1. Toxicology 144: 31-38 (2000). (Pubitemid 30201617)
4. M. Ofer, S. Wolffram, A. Koggel, H. Spahn-Langguth, and P. Langguth. Modulation of drug transport by selected flavonoids: Involvement of P-gpand OCT? Eur. J. Pharm. Sci. 25: 263-271 (2005). (Pubitemid 40725056)
5. F.I. Kanaze, E. Kokkalou, M. Georgarakis, and I. Niopase. Validated high-performance liquid chromatographic method utilizing solidphase extraction for the simultaneous determination of naringenin and hesperetinin human plasma. J. Chromatogr. B 801: 363-367 (2004). (Pubitemid 38130089)
6. T.Z. Fang, Y.G.Wang, Y.Ma,W.W. Su, Y. Bai, and P.Y. Zhao. A rapid LC/MS/MS quantitation assay for naringin and its two metabolites in rats plasma. J. Pharmaceut. Biomed. 40: 454-459 (2006). (Pubitemid 43143355)
7. A.Y. Jaime, X.W. Teng, A.R. Kathryn, and M.D. Neal. Stereospecific high-performance liquid chromatographic analysis of hesperetin in biological matrices. J. Pharmaceut. Biomed. 37: 591-595 (2005). (Pubitemid 40312306)
8. A.Y. Jaime and M.D. Neal. Stereospecific high-performance liquid chromatographic analysis of naringenin in urine. J. Pharmaceut. Biomed. 39: 164-169 (2005).
9. A.Y. Jaime, M.R. Connie, D.M. Nicole, R.V. Karina, K.A. Preston, M.D. Neal. Pharmacokinetics of selected chiral flavonoids: hesperetin, naringenin and eriodictyol in rats and their content in fruit juices. Biopharm. Drug. Dispos. 29: 63-82 (2008).