Failure and exploitation of autophagy in human pathologies - Cellular integrity between inflammation, infection, and cell survival

Seminars in Immunopathology

Volumn 32, Issue 4, 2010, Pages 319-322

  Kuballa, Petric ^a,b   Xavier, Ramnik J ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOPHAGY; CELL SURVIVAL; EDITORIAL; HUMAN; IMMUNOLOGY; INFECTION; INFLAMMATION; METABOLISM; PATHOLOGY;

AUTOPHAGY; CELL SURVIVAL; HUMANS; INFECTION; INFLAMMATION;

EID: 79953141007     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-010-0229-5     Document Type: Editorial

References (6)

1. Langer CC, Ejsmont RK, Schönbauer C, Schnorrer F, Tomancak P (2010) In vivo RNAi rescue in Drosophila melanogaster with genomic transgenes from Drosophila pseudoobscura. PLoSONE 5:e8928
2. Stappenbeck TS, Rioux JD, Mizoguchi A, Saitoh T, Huett A, Darfeuille-Michaud A, Wileman T, Mizushima N, Carding S, Akira S, Parkes M, Xavier RJ (2010) Crohn disease: a current perspective on genetics, autophagy and immunity. Autophagy 7:1-20
3. Martinez-Vicente M, Talloczy Z, Wong E, Tang G, Koga H, Kaushik S, de Vries R, Arias E, Harris S, Sulzer D, Cuervo AM (2010) Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease. Nat Neurosci 13:567-576
4. Lipinski MM, Zheng B, Lu T, Yan Z, Py BF, Ng A, Xavier RJ, Li C, Yankner BA, Scherzer CR, Yuan J (2010) Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease. Proc Natl Acad Sci USA 107:14164-14169
5. Zhu H, Wu H, Liu X, Li B, Chen Y, Ren X, Liu CG, Yang JM (2009) Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. Autophagy 6:816-823
6. Li Z, Chen B, Wu Y, Jin F, Xia Y, Liu X (2010) Genetic and epigenetic silencing of the beclin 1 gene in sporadic breast tumors. BMC Cancer 10:98