Structural basis for the methylation of A1408 in 16S rRNA by a panaminoglycoside resistance methyltransferase NpmA from a clinical isolate and analysis of the NpmA interactions with the 30S ribosomal subunit

Nucleic Acids Research

Volumn 39, Issue 5, 2011, Pages 1903-1918

  Husain, Nilofer ^a   Obranić, Sonja ^b   Koscinski, Lukasz ^c   Seetharaman, J ^d   Babić, Fedora ^b   Bujnicki, Janusz M ^a,c,e   Maravić Vlahoviek, Gordana ^b   Sivaraman, J ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b UNIVERSITY OF ZAGREB   (Croatia)

^c ADAM MICKIEWICZ UNIVERSITY   (Poland)

^d BROOKHAVEN NATIONAL LABORATORY   (United States)

^e INTERNATIONAL INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ENZYME; KANAMYCIN; METHYLTRANSFERASE; METHYLTRANSFERASE NPMA; RIBOSOME RNA; RNA 16S; RNA 30S; S ADENOSYLHOMOCYSTEINE; S ADENOSYLMETHIONINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ANALYSIS; ESCHERICHIA COLI; GENETIC VARIABILITY; ISOTHERMAL TITRATION CALORIMETRY; MINIMUM INHIBITORY CONCENTRATION; MOLECULAR DOCKING; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FOOTPRINTING; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; RNA METHYLATION;

ADENINE; BASE SEQUENCE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HUMANS; KANAMYCIN RESISTANCE; METHYLATION; METHYLTRANSFERASES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN FOOTPRINTING; RIBOSOME SUBUNITS, SMALL, BACTERIAL; RNA, RIBOSOMAL, 16S; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE;

ESCHERICHIA COLI;

EID: 79953138756     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkq1033     Document Type: Article

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