Advanced capabilities of the multimodal adaptive optics imager

Progress in Biomedical Optics and Imaging - Proceedings of SPIE

Volumn 7885, Issue , 2011, Pages

  Hammer, Daniel X ^a   Ferguson, R D ^a   Mujat, Mircea ^a   Biss, David P ^a   Iftimia, Nicusor V ^a   Patel, Ankit H ^a   Plumb, Emily ^a   Campbell, Melanie ^b   Norris, Jennifer L ^c   Dubra, Alfredo ^c   Chui, Toco Y P ^d   Akula, James D ^d   Fulton, Anne B ^d  

^a PHYSICAL SCIENCES INC   (United States)

^b UNIVERSITY OF WATERLOO   (Canada)

^c UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^d BOSTON CHILDREN S HOSPITAL   (United States)

Author keywords

Adaptive optics; deformable mirror; Fourier domain optical coherence tomography; ocular aberrations; ophthalmology; retinal imaging; scanning laser ophthalmoscopy; wavefront sensor

Indexed keywords

ANIMALS; LASER MIRRORS; OPHTHALMOLOGY; OPTICAL TOMOGRAPHY; RESEARCH LABORATORIES; SCANNING;

DEFORMABLE MIRRORS; FOURIER DOMAIN OPTICAL COHERENCE TOMOGRAPHY; OCULAR ABERRATIONS; RETINAL IMAGING; SCANNING LASER OPHTHALMOSCOPY; WAVE FRONT SENSORS;

ADAPTIVE OPTICS;

EID: 79953134974     PISSN: 16057422     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.876579     Document Type: Conference Paper

References (25)

1. J. Liang, D. R. Williams, and D. T. Miller, "Supernormal vision and high-resolution retinal imaging through adaptive optics," J. Opt. Soc. Am. A, 14, 2884-2892 (1997).
2. A. Roorda, F. Romero-Borja, W. I. Donnelly, H. Queener, T. Hebert, and M. Campbell, "Adaptive optics scanning laser ophthalmoscopy," Opt. Express, 10, 405-412 (2002).
3. R. J. Zawadzki, S. M. Jones, S. S. Olivier, M. Zhao, B. A. Bower, J. A. Izatt, S. Choi, S. Laut, and J. S. Werner, "Adaptive-optics optical coherence tomography for high-resolution and high-speed 3D retinal in vivo imaging," Opt. Express, 13, 8532-8546 (2005).
4. Y. Zhang, B. Cense, J. Rha, R. S. Jonnal, W. Gao, R. J. Zawadzki, J. S. Werner, S. Jones, S. Olivier, and D. T. Miller, "High-speed volumetric imaging of cone photoreceptors with adaptive optics spectral-domain optical coherence tomography," Opt. Express, 14, 4380-4394 (2006).
5. M. Mujat, R. D. Ferguson, A. H. Patel, N. Iftimia, N. Lue, and D. X. Hammer, "High resolution multimodal clinical ophthalmic imaging system," Opt. Express, 18, 11607-11621 (2010).
6. D. C. Gray, R. Wolfe, B. P. Gee, D. Scoles, Y. Geng, B. D. Masella, A. Dubra, S. Luque, D. R. Williams, and W. H. Merigan, "In Vivo Imaging of the Fine Structure of Rhodamine-Labeled Macaque Retinal Ganglion Cells," Invest. Ophthalmol. Vis. Sci., 49, 467-473 (2008).
7. T. P. Chui, H. Song, and S. A. Burns, "Adaptive-optics imaging of human cone photoreceptor distribution," J. Opt. Soc. Am. A, 25, 3021-3029 (2008).
8. A. Dubra, A. Gómez-Vieyra, Y. Sulai, and L. Díaz-Santana, "Optical Design of Clinical Adaptive Optics Instruments for Retinal Imaging," Frontiers in Optics, Rochester NY, (2010).
9. J. I. Wolfing, M. Chung, J. Carroll, A. Roorda, and D. R. Williams, "High-resolution retinal imaging of cone-rod dystrophy," Ophthalmology, 113, 1014-1019 (2006).
10. D. X. Hammer, N. V. Iftimia, R. D. Ferguson, C. E. Bigelow, T. E. Ustun, A. M. Barnaby, and A. B. Fulton, "Foveal Fine Structure in Retinopathy of Prematurity: An Adaptive Optics Fourier Domain Optical Coherence Tomography Study," Invest. Ophthalmol. Vis. Sci., 49, 2061-2070 (2008).
11. J. L. Duncan, K. E. Talcott, K. Ratnam, S. M. Sundquist, A. S. Lucero, S. Day,Y. Zhang, and A. Roorda, "Cone structure in retinal degeneration caused by mutations in the peripherin/RDS gene, " Invest. Ophthalmol. Vis. Sci., doi: 10.1167/iovs.10-6549 (2010).
12. K. E. Talcott, K. Ratnam, S. M. Sundquist, A. S. Lucero, B. J. Lujan, W. Tao, T. C. Porco, A. Roorda, and J. L. Duncan, "Longitudinal study of cone photoreceptors during retinal degeneration and in response to ciliary neurotrophic factor treatment," Invest. Ophthalmol. Vis. Sci., doi: 10.1167/iovs.10-6479 (2010).
13. B. Potsaid, I. Gorczynska, V. J. Srinivasan, Y. Chen, J. Jiang, A. Cable, and J. G. Fujimoto, "Ultrahigh speed Spectral / Fourier domain OCT ophthalmic imaging at 70,000 to 312,500 axial scans per second," Opt. Express, 16, 15149-15169 (2008).
14. D. C. Gray, W. Merigan, J. I. Wolfing, B. P. Gee, J. Porter, A. Dubra, T. H. Twietmeyer, K. Ahamd, R. Tumbar, F. Reinholz, and D. R. Williams, "In vivo fluorescence imaging of primate retinal ganglion cells and retinal pigment epithelial cells," Opt. Express, 14, 7144-7158 (2006).
15. K. Grieve, P. Tiruveedhula, Y. Zhang, and A. Roorda, "Multi- wavelength imaging with the adaptive optics scanning laser ophthalmoscope," Opt. Express, 14, 12230-12242 (2006).
16. R. D. Ferguson, D. X. Hammer, A. E. Elsner, R. H. Webb, S. A. Burns, and J. J. Weiter, "Wide-field retinal hemodynamic imaging with the tracking scanning laser ophthalmoscope," Opt. Express 12, 5198-5208 (2004).
17. D. X. Hammer, R. D. Ferguson, T. E. Ustun, C. E. Bigelow, N. V. Iftimia, R. H. Webb, "Line-scanning laser ophthalmoscope," J. Biomed. Opt., 11, 041126 (2006).
18. J. D. Akula, J. A. Mocko, I. Y. Benador, R. M. Hansen, T. L. Favazza, T. C. Vyhovsky, and A. B. Fulton, "The neurovascular relation in oxygen-induced retinopathy," Molecular Vision 14, 2499-2508 (2008).
19. T. E. Ustun, N. V. Iftimia, R. D. Ferguson, and D. X. Hammer, "Real-time processing for Fourier domain optical coherence tomography using a field programmable gate array," Rev. Sci. Instrum., 79, 114301 (2008).
20. M. Mujat, R. D. Ferguson, N. V. Iftimia, and D. X. Hammer, "Compact adaptive optics line scanning ophthalmoscope," Opt Express, 17, 10242-10258 (2009).
21. A. Dubra and Z. Harvey, "Registration of 2D Images from Fast Scanning Ophthalmic Instruments," Lecture Notes in Computer Sciences, Workshop on Biomedical Image Registration, B. Fischer, B. Dawant, and C. Lorenz (Eds.): 6204, 60-71 (2010).
22. J. D. Akula, T. L. Favazza, J. A. Mocko, I. Y. Benador, A. L. Asturias, M. S. Kleinman, et al., "The anatomy of the rat eye with oxygen-induced retinopathy," Doc. Ophthalmol., 120, 41-50 (2010).
23. B. Potsaid, B. Baumann, D. Huang, S. Barry, A. E. Cable, J. S. Schuman, J. S. Duker, and J. G. Fujimoto, "Ultrahigh speed 1050nm swept source / Fourier domain OCT retinal and anterior segment imaging at 100,000 to 400,000 axial scans per second," Opt. Express 18, 20029-20048 (2010).
24. O. P. Kocaoglu, S. Lee, Q. Wang, A. E. Herde, J. Besecker, W. Gao, R. S. Jonnal, and D. T. Miller, "3D imaging of cone photoreceptors over extended time periods using optical coherence tomography with adaptive optics," in Ophthalmic Technologies XXI, SPIE Vol. 7885, Paper 7885-10 (2011).
25. M. Pircher, E. Götzinger, H. Sattmann, R. A. Leitgeb, and C. K. Hitzenberger, "In vivo investigation of human cone photoreceptors with SLO/OCT in combination with 3D motion correction on a cellular level," Opt. Express, 18, 13935-13944 (2010).