Prolonged mechanical ventilation in critically ill patients: Epidemiology, outcomes and modelling the potential cost consequences of establishing a regional weaning unit

Critical Care

Volumn 15, Issue 2, 2011, Pages

  Lone, Nazir I ^a   Walsh, Timothy S ^b  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b ROYAL INFIRMARY OF EDINBURGH   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ARTIFICIAL VENTILATION; COHORT ANALYSIS; CRITICALLY ILL PATIENT; FEMALE; HEALTH CARE COST; HOSPITAL BED UTILIZATION; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; UNITED KINGDOM; AGED; CRITICAL ILLNESS; ECONOMICS; HEALTH CARE PLANNING; INTENSIVE CARE; MIDDLE AGED; ORGANIZATION AND MANAGEMENT; STATISTICAL MODEL; STATISTICS; TIME; TREATMENT OUTCOME;

ADULT; AGED; CRITICAL CARE; CRITICAL ILLNESS; FEMALE; GREAT BRITAIN; HEALTH RESOURCES; HUMANS; INTENSIVE CARE UNITS; MALE; MIDDLE AGED; MODELS, ECONOMIC; REGIONAL HEALTH PLANNING; RESPIRATION, ARTIFICIAL; RETROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; VENTILATOR WEANING;

EID: 79953119233     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/cc10117     Document Type: Article

References (31)

1. Comprehensive critical care: a review of adult critical care services. , http://www.dh.gov.uk/en/Publicationsandstatistics/Publications/PublicationsPolicyAndGuidance/DH_4006585
2. MacIntyre NR, Epstein SK, Carson S, Scheinhorn D, Christopher K, Muldoon S. Management of patients requiring prolonged mechanical ventilation - report of a NAMDRC consensus conference. Chest 2005, 128:3937-3954. 10.1378/chest.128.6.3937, 16354866.
3. Zilberberg MD, de Wit M, Pirone JR, Shorr AF, Zilberberg MD, de Wit M, Pirone JR, Shorr AF. Growth in adult prolonged acute mechanical ventilation: implications for healthcare delivery. Crit Care Med 2008, 36:1451-1455. 10.1097/CCM.0b013e3181691a49, 18434911.
4. Robson V, Poynter J, Lawler PG, Baudouin SV. The need for a regional weaning centre, a one-year survey of intensive care weaning delay in the Northern Region of England. Anaesthesia 2003, 58:161-165. 10.1046/j.1365-2044.2003.02964_1.x, 12622105.
5. Zilberberg MD, Luippold RS, Sulsky S, Shorr AF, Zilberberg MD, Luippold RS, Sulsky S, Shorr AF. Prolonged acute mechanical ventilation, hospital resource utilization, and mortality in the United States. Crit Care Med 2008, 36:724-730. 10.1097/CCM.0B013E31816536F7, 18209667.
6. Kahn JM, Benson NM, Appleby D, Carson SS, Iwashyna TJ, Kahn JM, Benson NM, Appleby D, Carson SS, Iwashyna TJ. Long-term acute care hospital utilization after critical illness. JAMA 2010, 303:2253-2259. 10.1001/jama.2010.761, 20530778.
7. Mauri T, Pivi S, Bigatello LM. Prolonged mechanical ventilation after critical illness. Minerva Anestesiol 2008, 74:297-301.
8. Scheinhorn DJ, Artinian BM, Catlin JL. Weaning from prolonged mechanical ventilation - the experience at a regional weaning center. Chest 1994, 105:534-539. 10.1378/chest.105.2.534, 8306758.
9. Critical care programme: weaning and long term ventilation. , http://www.ics.ac.uk/intensive_care_professional/critical_care_programme_-_weaning_and_long_term_ventilation_
10. Scottish Intensive Care Society Audit Group. , http://www.sicsag.scot.nhs.uk/
11. Scottish Intensive Care Society Audit Group annual report: audit of intensive care units in Scotland 2010 reporting on 2009. , http://www.sicsag.scot.nhs.uk/Publications/SICSAG-report-2010-web-version.pdf
12. PPPs and exchange rates. , http://stats.oecd.org/Index.aspx?datasetcode=SNA_TABLE4
13. Rehabilitation after critical illness. Clinical guideline 83. , http://www.nice.org.uk/nicemedia/pdf/CG083NICEGuideline.pdf
14. Kirkwood B, Sterne J. Essential Medical Statistics 2003, Oxford: Wiley-Blackwell.
15. Smith IE, Shneerson JM. A progressive care program for prolonged ventilatory failure - analysis of outcome. Br J Anaesth 1995, 75:399-404.
16. Reddy SLC, Grayson AD, Griffiths EM, Pullan DM, Rashid A. Logistic risk model for prolonged ventilation after adult cardiac surgery. Ann Thorac Surg 2007, 84:528-536. 10.1016/j.athoracsur.2007.04.002, 17643630.
17. Rajakaruna C, Rogers CA, Angelini GD, Ascione R. Risk factors for and economic implications of prolonged ventilation after cardiac surgery. J Thorac Cardiovasc Surg 2005, 130:1270-1277.
18. Kress JP, Pohlman AS, O'Connor MF, Hall JB. Daily interruption of sedative infusions in critically ill patients undergoing mechanical ventilation. New Engl J Med 2000, 342:1471-1477. 10.1056/NEJM200005183422002, 10816184.
19. Girard TD, Kress JP, Fuchs BD, Thomason JWW, Schweickert WD, Pun BT, Taichman DB, Dunn JG, Pohlman AS, Kinniry PA, Jackson JC, Canonico AE, Light RW, Shintani AK, Thompson JL, Gordon SM, Hall JB, Dittus RS, Bernard GR, Ely EW. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008, 371:126-134. 10.1016/S0140-6736(08)60105-1, 18191684.
20. Blackwood B, Alderdice F, Burns K, Cardwell C, Lavery G, O'Halloran P. Use of weaning protocols for reducing duration of mechanical ventilation in critically ill adult patients: Cochrane systematic review and meta-analysis. BMJ 2011, 342:c7237. 10.1136/bmj.c7237, 3020589, 21233157.
21. Jegers M, Edbrooke DL, Hibbert CL, Chalfin DB, Burchardi H. Definitions and methods of cost assessment: an intensivist's guide. ESICM section on health research and outcome working group on cost effectiveness. Intensive Care Med 2002, 28:680-685. 10.1007/s00134-002-1279-5, 12107670.
22. Estenssoro E, Gonzalez F, Laffaire E, Canales H, Saenz G, Reina R, Dubin A. Shock on admission day is the best predictor of prolonged mechanical ventilation in the ICU. Chest 2005, 127:598-603. 10.1378/chest.127.2.598, 15706002.
23. Cox CE, Carson SS, Lindquist JH, Olsen MK, Govert JA, Chelluri L, Cox CE, Carson SS, Lindquist JH, Olsen MK, Govert JA, Chelluri L. Quality of Life After Mechanical Ventilation in the Aged I Differences in one-year health outcomes and resource utilization by definition of prolonged mechanical ventilation: a prospective cohort study. Crit Care 2007, 11:R9. 10.1186/cc5667, 2147069, 17244364, Quality of Life After Mechanical Ventilation in the Aged I.
24. Cox CE, Carson SS, Holmes GM, Howard A, Carey TS, Cox CE, Carson SS, Holmes GM, Howard A, Carey TS. Increase in tracheostomy for prolonged mechanical ventilation in North Carolina, 1993-2002. Crit Care Med 2004, 32:2219-2226.
25. Dasgupta A, Rice R, Mascha E, Litaker D, Stoller JK. Four-year experience with a unit for long-term ventilation (Respiratory Special Care Unit) at the Cleveland Clinic Foundation. Chest 1999, 116:447-455. 10.1378/chest.116.2.447, 10453875.
26. Elpern EH, Larson R, Douglass P, Rosen RL, Bone RC. Long-term outcomes for elderly survivors of prolonged ventilator assistance. Chest 1989, 96:1120-1124. 10.1378/chest.96.5.1120, 2509150.
27. Carson SS, Bach PB, Brzozowski L, Leff A. Outcomes after long-term acute care - An analysis of 133 mechanically ventilated patients. Am J Respir Crit Care Med 1999, 159:1568-1573.
28. Scheinhorn DJ, Hassenpflug MS, Votto JJ, Chao DC, Epstein SK, Doig GS, Knight EB, Petrak RA. Post-ICU mechanical ventilation at 23 long-term care hospitals - A multicenter outcomes study. Chest 2007, 131:85-93. 10.1378/chest.06-1081, 17218560.
29. Bigatello LM, Stelfox HT, Berra L, Schmidt U, Gettings EM, Bigatello LM, Stelfox HT, Berra L, Schmidt U, Gettings EM. Outcome of patients undergoing prolonged mechanical ventilation after critical illness. Crit Care Med 2007, 35:2491-2497. 10.1097/01.CCM.0000287589.16724.B2, 17901840.
30. Scheinhorn DJ, Chao DC, Hassenpflug MS, Gracey DR. Post-ICU weaning from mechanical ventilation: the role of long-term facilities. Chest 2001, 120:482S-484S. 10.1378/chest.120.6_suppl.482S, 11742970.
31. Seneff MG, Wagner D, Thompson D, Honeycutt C, Silver M. The impact of long-term acute-care facilities on the outcome and cost of care for patients undergoing prolonged mechanical ventilation. Crit Care Med 2000, 28:342-350. 10.1097/00003246-200002000-00009, 10708164.