A phase II study of weekly cisplatine plus oral vinorelbine with concomittant radiotherapy in non-dependent elderly patients with localized inoperable non small cell lung carcinoma (Essai GFPC 08-06, Raccosa);Radio-chimiothérapie concomitante chez le sujet âgé indépendant (Essai GFPC 0806 RACCOSA)

Revue des Maladies Respiratoires

Volumn 28, Issue 1, 2011, Pages 58-65

  Locher, C ^a   Pourel, N ^b   Marin, B ^c   Vergnenegre A ^c  

^a CENTRE HOSPITALIER DE MEAUX   (France)

^b INSTITUT SAINTE CATHERINE   (France)

^c Hopital du Cluzeau   (France)

Author keywords

Concomitant radiochemotherapy; Elderly patients; Non small cell lung cancer

Indexed keywords

CISPLATIN; NAVELBINE;

ADVANCED CANCER; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER LOCALIZATION; CANCER RADIOTHERAPY; CHEMORADIOTHERAPY; CLINICAL TRIAL; DRUG TOLERABILITY; HUMAN; LUNG SMALL CELL CANCER; MAJOR CLINICAL STUDY;

AGED; AGED, 80 AND OVER; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CARCINOMA, NON-SMALL-CELL LUNG; CISPLATIN; COMBINED MODALITY THERAPY; DISEASE-FREE SURVIVAL; DRUG ADMINISTRATION SCHEDULE; FEMALE; FOLLOW-UP STUDIES; FRANCE; HUMANS; LUNG NEOPLASMS; MALE; NEOPLASM STAGING; QUALITY OF LIFE; RADIOTHERAPY DOSAGE; VINBLASTINE;

EID: 79953105825     PISSN: 07618425     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rmr.2010.04.019     Document Type: Article

References (23)

1. Molinié F, Velten M, Remontet L, Bercelli P, et le réseau Francim. Évolution de l'incidence du CBP en France (1978-2000). Rev Mal Respir 2006;23:127-34. (Pubitemid 43926736)
2. Bercelli P. Évolution de l'incidence et de la mortalité par cancer en France de 1978 à 2000. Poumon. Rapport du Réseau français des registres du cancer, Francim, hôpitaux de Lyon, Institut national de la santé et de la recherche médicale, Inserm, Institut de veille sanitaire, In-S. Août 2003:79-85.
3. Blanchon F, Grivaux M, Collon T, Zureik M, Barbieux H, Bénichou-Flurin M, et al. Épidémiologie du cancer bronchique primitif pris en charge dans les centres hospitaliers généraux français. Étude KBP-2000-CPHG du Collège des pneumologues des hôpitaux généraux (CPHG). Rev Mal Respir 2002;19:727-34. (Pubitemid 36019711)
4. Souquet PJ, Lombard-Bohas CH, Freyer G, Bombaron P, Gernière L, Bernard JP. Chimiothérapie des cancers bronchiques des sujets âgés. Rev Mal Resp 1996;13:327-33. (Pubitemid 26312809)
5. Balducci L, Extermann M. Management of cancer in the older person: a practical approach. Oncologist 2000;5:224-37. (Pubitemid 30429942)
6. Dujon C, Azarian R, Azarian V, Petitpretz P. Cancer bronchique du sujet âgé: performance status et/ou indices gériatriques? Rev Mal Respir 2006;23:307-18. (Pubitemid 44645738)
7. Dale DC. Poor prognosis in elderly patients with cancer: the role of bias and undertreatment. J Support Oncol 2003;1:11-7.
8. Mountain CF. Revisions in the International System for Staging Lung cancer. Chest 1997;111:1710-7. (Pubitemid 27260107)
9. Dillman RO, Herndon J, Seagren SL, Eaton Jr WL, Green MR. Improved survival in stage III non-small-cell lung cancer: seven-year follow-up of cancer and leukemia group B (CALGB) 8433 trial. J Natl Cancer Inst 1996;88:1210-5. (Pubitemid 26302034)
10. Le Chevalier T, Arriagada R, Quoix E, Ruffie P, Martin M, Tarayre M, et al. Radiotherapy alone versus combined chemotherapy and radiotherapy in nonresectable non-small-cell lung cancer: first analysis of a randomized trial in 353 patients. J Natl Cancer Inst 1991;83:417-23.
11. Non Small Cell Lung Cancer Collaborative Group. Chemotherapy in non small cell lung cancer: a meta-analysis using updated data on individual patients from 52 randomised clinical trials. BMJ 1995;311:899-909.
12. Furuse K, Fukuoka M, Kawahara M, Nishikawa H, Takada Y, Kudoh S, et al. Phase III study of concurrent versus sequential thoracic radiotherapy in combination with mitomycin, vindesine, and cisplatin in unresectable stage III non-small-cell lung cancer. J Clin Oncol 1999;17:2692-9. (Pubitemid 29415225)
13. Curran WJ, Scott CB, Langer CJ, Komaki R, Lee J, Hauser S, et al. Long-term benefit is observed in a phase III comparaison of sequential vs concurrent chemo-radiation for patients with unresectable stage III nsclc: RTOG 94-10. Proc Am Soc Clin Oncol 2003:22.
14. Fournel P, Robinet G, Thomas P, Souquet PJ, Léna H, Vergnenègre A, et al. Randomized phase III trial of sequential chemoradiotherapy versus concurrent chemoradiotherapy in locally advanced non-small cell lung cancer: Groupe Lyon-Saint-Étienne d'oncologie thoracique-Groupe français de pneumo-cancérologie NPC 95-01 Study. J Clin Oncol 2005;23:5910-7.
15. Aupérin A, Le Péchoux C, Rolland E, Curran WJ, Furuse K, Fournel P, et al. Meta-analysis of concomitant versus sequential radiochemotherapy in locally advanced non-small-cell lung cancer. J Clin Oncol 2010;28(13):2181-90.
16. Edelstein MP, Wolfe LA, Duch DS. Potentiation of radiation therapy by vinorelbine (Navelbine) in non-small cell lung cancer. Semin Oncol 1996;23:41-7. (Pubitemid 26130114)
17. Masters GA, Haraf DJ, Hoffman PC, et al. Phase I study of vinorelbine, cisplatin, and concomitant thoracic radiation in the treatment of advanced chest malignancies. J Clin Oncol 1998;16:2157-63. (Pubitemid 28265053)
18. Hurria A, Kris MG. Management of lung cancer in older adults. CA Cancer J Clin 2003;53:325-41. (Pubitemid 38081591)
19. Movsas B, Scott C, Sause W, Byhardt R, Komaki R, Cox J, et al. The benefit of treatment intensification is age and histologydependent in patients with locally advanced non-small cell lung cancer (NSCLC): a quality-adjusted survival analysis of radiation therapy oncology group (RTOG) chemoradiation studies. Int J Radiat Oncol Biol Phys 1999;45:1143-9.
20. Langer CJ, Hsu C, Curran W, Komaki R, Lee JS, Byhardt R, et al. Do elderly patients (pts) with locally advanced Non-Small Cell Lung Cancer (NSCLC) benefit from combined modality therapy? A secondary analysis of RTOG 94-10. Int J Radiat Oncol Biol Phys 2001;51:20-1.
21. Pignon T, Gregor A, Schaake Koning C, Roussel A, Van Glabbeke M, Scalliet P. Age has no impact on acute and late toxicity of curative thoracic radiotherapy. Radiother Oncol 1998;46:239-48. (Pubitemid 28157273)
22. Semrau S, Bier A, Thierbach U, Virchow C, Ketterer P, Fietkau R. Concurrent radiochemotherapy with vinorelbine plus cisplatin or carboplatin in patients with locally advanced non-small-cell lung cancer (NSCLC) and an increased risk of treatment complications. Preliminary results. Strahlenther Onkol 2003;179:823-31. (Pubitemid 37509470)
23. Jeremic B, Shibamoto Y, Milicic B, Milisavljevic S, Nikolic N, Dagovic A, et al. A phase II study of concurrent accelerated hyperfractionated radiotherapy and carboplatin/oral etoposide for elderly patients with stage III non-smallcell lung cancer. Int J Radiat Oncol Biol Phys 1999;44:343-8. (Pubitemid 29205032)