Anticonvulsant evaluation of safranal in pentylenetetrazole-induced status epilepticus in mice

International Journal of Essential Oil Therapeutics

Volumn 3, Issue 2-3, 2009, Pages 106-108

  Pathan, S A ^a   Zaidi, S M A ^a   Jain, G K ^a   Vohora, D ^a   Ahmad, F J ^a   Khar, R K ^a  

^a HAMDARD UNIVERSITY   (India)

Author keywords

Essential oil; PTZ; Safranal; Seizures; Status epilepticus

Indexed keywords

ANTICONVULSIVE AGENT; DIAZEPAM; ESSENTIAL OIL; PENTETRAZOLE; PHENYTOIN; SAFRANAL; TERPENE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTICONVULSANT ACTIVITY; ARTICLE; BRAIN PROTECTION; CONTROLLED STUDY; CROCUS; CROCUS SATIVUS; DOSE RESPONSE; DRUG MECHANISM; EPILEPTIC STATE; MALE; MOUSE; NONHUMAN;

EID: 79953103221     PISSN: 19614209     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Raines A, Henderson TR, Swinyard EA, Kenneth LD. Comparison of midazolam and diazepam by the intramuscular route for the control of seizures in a mouse model of status epilepticus. Epilepsia. 1990;31:313-17. (Pubitemid 20181301)
2. Abdullaev FJ. Biological effects of saffron. Biofactors. 1993;4:83-86.
3. Hosseinzadeha H, Sadeghniab HR. Protective effect of safranal on pentylenetetrazol-induced seizures in the rat: Involvement of GABAergic and opioids systems. Phytomed. 2007;14:256-62.
4. Hosseinzadeh H, Talebzadeh F Anticonvulsant evaluation of safranal and crocin from Crocus sativus in mice. Fitoterapia. 2005;76:722-24. (Pubitemid 41688398)
5. Ali A, Pillai KK, Ahmad FJ, Dua Y, Vohora D. Anticonvulsant effect of amiloride in pentetrazole-induced status epilepticus in mice. Pharmacol Rep. 2006;58:242-45.