Variation in podophyllotoxin concentration in leaves and rhizomes of American mayapple (Podophyllum peltatum L.)

Industrial Crops and Products

Volumn 33, Issue 3, 2011, Pages 633-637

  Zheljazkov, Valtcho D ^a,b   Cantrell, Charles L ^c   Astatkie, Tess ^d  

^a MISSISSIPPI STATE UNIVERSITY   (United States)

^b UNIVERSITY OF WYOMING   (United States)

^c NATURAL PRODUCTS UTILIZATION RESEARCH UNIT   (United States)

^d DALHOUSIE UNIVERSITY   (Canada)

Author keywords

Leaves; Mayapple; Podophyllotoxin; Podophyllum; Roots

Indexed keywords

LEAVES; MAYAPPLE; PODOPHYLLOTOXIN; PODOPHYLLUM; ROOTS;

CROPS; SODIUM; SOILS;

CONCENTRATION (PROCESS);

CONCENTRATION (COMPOSITION); DICOTYLEDON; DRUG; LEAF; PHYTOCHEMISTRY; RHIZOME; ROOT SYSTEM; SOIL NUTRIENT; SOIL ORGANIC MATTER; TOXIN;

PODOPHYLLUM; PODOPHYLLUM PELTATUM; SINOPODOPHYLLUM HEXANDRUM;

EID: 79953101585     PISSN: 09266690     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.indcrop.2010.12.025     Document Type: Article

References (26)

1. Ayres D.C., Loike J.D. Lignans: Chemical, Biological, and Clinical Properties 1990, Cambridge Univ. Press, Cambridge, UK.
2. Bedir E., Khan I., Moraes R.M. Bioprospecting for podophyllotoxin. Trends in New Crops and New Uses 2002, 545-549. ASHS Press, Alexandria, VA. J. Janick, A. Whipkey (Eds.).
3. Bedir E., Tellez M., Lata H., Khan I., Cushman K.E., Moraes R.M. Post-harvest and scale-up extraction of American mayapple leaves for podophyllotoxin production. Ind. Crop Prod. 2006, 24:3-7.
4. Bogdanova V.P., Sokolov V.S. Developmental features of Podophyllum peltatum L. and Podophyllum emodii Wall: In cultivation conditions in the Lvov province. Herba Polonica 1973, 19:379-384.
5. Canel C., Dayan F.E., Ganzera M., Rimando A., Burandt C., Khan I., Moraes R.M. Increased yield of podophyllotoxin from leaves of Podophyllum peltatum by in situ conversion of podophyllotoxin 4-O-b-d glucopyranoside. Planta Med. 2001, 67:97-99.
6. Cox M.S. The Lancaster soil test method as an alternative to the Mehlich 3 soil test method. Soil Sci. 2001, 166:484-489.
7. Cushman K.E., Maqbool M. Propagule type and planting time affect subsequent mayapple growth. HortScience 2005, 40(3):640-644.
8. Cushman K.E., Maqbool M., Gerard P.D. Mulch type, mulch depth, and rhizome planting depth for field grown American mayapple. HortScience 2005, 40(3):635-639.
9. Cushman K.E., Maqbool M., Gerard P.D., Bedir E., Lata H., Moraes R.M. Variation of prodophyllotoxin in leaves of eastern red cedar (Juniperus virginiana). Planta Med. 2003, 69:477-478.
10. Cushman K.E., Maqbool M., Lata H., Bedir E., Khan I.A., Moraes R.M. Podophyllotoxin content and yield of American mayapple leaves in sun and shade. HortScience 2005, 40(1):60-63.
11. Cushman K.E., Maqbool M., Moraes R. Type of propagule and time of planting affect first year of field-established mayapple (Podophyllum peltatum). Trends in New Crops and New Uses 2001, 533-536. ASHS Press, Alexandria, VA. J. Janick (Ed.).
12. Farkya S., Bisaria V.S., Srivastava A.K. Biotechnological aspects of the production of the anticancer drug podophyllotoxin. Appl. Microbiol. Biotechnol. 2004, 65:504-519.
13. Gawde A.J., Zheljazkov V.D., Maddox V., Cantrell C.L. Bioprospection of eastern red cedar from nine physiographic regions in Mississippi. Ind. Crop Prod. 2009, 30:59-64.
14. Gordaliza M., Garcia P.A., Miguel el Corral J.M., Castro M.A., Comez-Zurita M.A. Podophyllotoxin: distribution, sources, applications and new cytotoxic derivatives. Toxicon 2004, 44:441-459.
15. Holthuis J.J.M. Etoposide and teniposide: bioanalysis, metabolism and clinical pharmokinetics. Pharm. Weekbl. 1988, 10:101-116.
16. Ionkova I. Biotechnological approaches for the production of lignans. Pharm. Rev. 2007, 1:57-68.
17. Kohlmunzer S., Kosch A., Danek H. Lignan compounds of Podophyllum peltatum L. cultivated in Poland. Poznan Inst. Przemyslu Zielarkiego Biul. 1971, 17:110-117.
18. Kuznetsova G.A., Bogdanova V.P. The dynamics of the accumulation of podophyllin and the change in its qualitative composition in Podophyllum peltatum L. cultivated in the Leningrad region. Rastitel. Resursy 1970, 6:240-243.
19. Meijer W. Podophyllum peltatum-mayapple: a potential new cash crop plant of eastern North America. Econ. Bot. 1974, 28:68-72.
20. Moraes R.M., Bedir E., Barrett H., Burandt C., Canel C., Khan I. Evaluation of Podophyllum peltatum L. accessions for podophyllotoxin production. Planta Med. 2001, 68:341-344.
21. Moraes R.M., Lata H., Bedir E., Maqbool M., Cushman K. The American mayapple and its potential for podophyllotoxin production. Trends in New Crops and New Uses 2001, 527-532. ASHS Press, Alexandria, VA. J. Janick (Ed.).
22. Mukherjee A.K., Basu S., Sarkar N., Ghosh A.C. Advances in cancer therapy with plant based natural products. Curr. Med. Chem. 2001, 8:1467-1468.
23. Saraeva P.I. Mayapple. Medicinal Plants and Their Cultivation 1952, Medgiz, Moscow, Russia, pp. 273-274. P.I. Saraeva (Ed.).
24. Stahelin H.F., von Wartburg A.V. The chemical and biological route from podophyllotoxin glucoside to etoposide. Cancer Res. 1991, 51:5-15.
25. Sultan P., Shawl A.S., Ramteke P.W., Kour A., Qazi P.H. Assessment of diversity of Podophyllum hexandrum by genetic and phytochemical markers. Sci. Horticult. 2008, 115:398-408.
26. Zheljazkov V.D., Avula B., Jones A.M., Maddox V., Rowe D.E. Lignan and nutrient concentrations in American mayapple (Podophyllum peltatum L.) in the eastern United States. HortScience 2009, 44(2):349-353.