Cytomegalovirus DNA retrieval in the inner ear fluids of a congenitally deaf child one month after primary infection: A Case Report

Laryngoscope

Volumn 121, Issue 4, 2011, Pages 828-830

  Di Nardo, Walter ^a   Cattani, Paola ^b   Scorpecci, Alessandro ^a,c   Giannantonio, Sara ^a   D'Onghia, Sara ^b   Fadda, Giovanni ^b   Paludetti, Gaetano ^a  

^a Department of Otorhinolaryngology ^*  (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c FONDAZIONE POLICLINICO UNIVERSITARIO A GEMELLI IRCCS   (Italy)

Author keywords

acquired cytomegalovirus infection; Cochlear implants; GJB2 mutation; real time polymerase chain reaction

Indexed keywords

CONNEXIN 26; CYTOMEGALOVIRUS ANTIBODY; VIRUS DNA;

ARTICLE; CASE REPORT; CHILD; CLINICAL FEATURE; COCHLEA; COCHLEA PROSTHESIS; COMPUTER ASSISTED TOMOGRAPHY; CONGENITAL DEAFNESS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTION; GENE MUTATION; HUMAN; INNER EAR; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PERILYMPH; PHYSICAL EXAMINATION; POLYMERASE CHAIN REACTION; PRIMARY INFECTION; PRIORITY JOURNAL; SEROLOGY; VIRUS LOAD;

CHROMOSOME DELETION; COCHLEAR IMPLANTATION; CONNEXINS; CYTOMEGALOVIRUS; CYTOMEGALOVIRUS INFECTIONS; DEAFNESS; DNA, VIRAL; ENDOLYMPH; HOMOZYGOTE; HUMANS; INFANT; MALE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 79953086012     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1002/lary.21447     Document Type: Article

References (8)

1. Bachor E, Sudhoff H, Litschel R, Karmody CS,. The pathology of the temporal bones of a child with acquired cytomegalovirus infection: studies by light microscopy, immunohistochemistry and polymerase-chain reaction. Int J Ped Otorhinolaryngol 2000; 55: 215-224.
2. Pass RF,. Congenital cytomegalovirus infection and hearing loss. Herpes 2005; 12: 50-55. (Pubitemid 41512784)
3. Sugiura S, Yoshikawa T, Nishiyama Y, et al. Detection of human CMV DNA in perilymph of patients with sensorineural hearing loss using real time-PCR. J Med Virol 2003; 69: 72-73.
4. White DR, Choo DI, Stroup G, Schleiss MR,. The effect of cidofovir on cytomegalovirus-induced hearing loss in a guinea pig model. Arch Otolaryngol Head Neck Surg 2006; 132: 608-615. (Pubitemid 43927037)
5. Di Nardo W, Cattani P, Lopizzo T, et al. Multiple viral genome search in endolabyrinthic fluids of profoundly deaf patients: possible CMV intracochlear reactivation. Audiol Neurootol 2009; 14: 290-295.
6. Gandhi MT, Khanna R,. Human cytomegalovirus: clinical aspects, immune regulation, and emerging treatments. Lancet Infect Dis 2004; 4: 725-738. (Pubitemid 39574344)
7. Ross SA, Novak Z, Kumbla RA, Zhang K, Fowler KB, Boppana S,. GJB2 and GJB6 mutations in children with congenital cytomegalovirus infection. Pediatr Res 2007; 61: 687-691. (Pubitemid 46800277)
8. Bauer PW, Parizi-Robinson M, Roland PS, Yegappan S,. Cytomegalovirus in the perilymphatic fluid. Laryngoscope 2005; 115: 223-225. (Pubitemid 40216692)