Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle

Experimental Cell Research

Volumn 317, Issue 8, 2011, Pages 1169-1178

  von Maltzahn, Julia ^a   Wulf, Volker ^a   Matern, Gabi ^a   Willecke, Klaus ^a  

^a UNIVERSITY OF BONN   (Germany)

Author keywords

Connexin; Gap junction; Muscle regeneration; Myogenesis

Indexed keywords

ACTIN; CD11B ANTIGEN; CONNEXIN 39; CONNEXIN 43; ENHANCED GREEN FLUORESCENT PROTEIN; GAP JUNCTION PROTEIN; MYOD PROTEIN; MYOGENIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; EMBRYO; GENE; GJD4 GENE; MALE; MOUSE; MUSCLE DEVELOPMENT; MUSCLE REGENERATION; MYOBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SATELLITE CELL; SKELETAL MUSCLE; UPREGULATION; WILD TYPE;

MUS;

EID: 79953072980     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2011.01.017     Document Type: Article

References (43)

1. Parker M.H., Seale P., Rudnicki M.A. Looking back to the embryo: defining transcriptional networks in adult myogenesis. Nat. Rev. 2003, 4:497-507.
2. Davis R.L., Weintraub H., Lassar A.B. Expression of a single transfected cDNA converts fibroblasts to myoblasts. Cell 1987, 51:987-1000.
3. Braun T., Buschhausen-Denker G., Bober E., Tannich E., Arnold H.H. A novel human muscle factor related to but distinct from MyoD1 induces myogenic conversion in 10T1/2 fibroblasts. EMBO J. 1989, 8:701-709.
4. Wright W.E., Sassoon D.A., Lin V.K. Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD. Cell 1989, 56:607-617.
5. Rhodes S.J., Konieczny S.F. Identification of MRF4: a new member of the muscle regulatory factor gene family. Genes Dev. 1989, 3:2050-2061.
6. Rudnicki M.A., Le Grand F., McKinnell I., Kuang S. The molecular regulation of muscle stem cell function. Cold Spring Harb. Symp. Quant. Biol. 2009, 83:1359-1400.
7. Ordahl C.P., Williams B.A., Denetclaw W. Determination and morphogenesis in myogenic progenitor cells: an experimental embryological approach. Curr. Top. Dev. Biol. 2000, 48:319-367.
8. Charge S.B., Rudnicki M.A. Cellular and molecular regulation of muscle regeneration. Physiol. Rev. 2004, 84:209-238.
9. Hawke T.J., Garry D.J. Myogenic satellite cells: physiology to molecular biology. J. Appl. Physiol. 2001, 91:534-551.
10. Constantin B., Cronier L. Involvement of gap junctional communication in myogenesis. Int. Rev. Cytol. 2000, 196:1-65.
11. von Maltzahn J., Willecke K. Essential role of gap junctions during development and regeneration of skeletal muscle, gap junctions. Development and Disease 2005, 13-27. E. Winterhager (Ed.).
12. Zammit P.S., Partridge T.A., Yablonka-Reuveni Z. The skeletal muscle satellite cell: the stem cell that came in from the cold. J. Histochem. Cytochem. 2006, 54:1177-1191.
13. Zammit P.S. All muscle satellite cells are equal, but are some more equal than others?. J. Cell Sci. 2008, 121:2975-2982.
14. Grounds M.D. Reasons for the degeneration of ageing skeletal muscle: a central role for IGF-1 signalling. Biogerontology 2002, 3:19-24.
15. Cornelison D.D., Wold B.J. Single-cell analysis of regulatory gene expression in quiescent and activated mouse skeletal muscle satellite cells. Dev. Biol. 1997, 191:270-283.
16. Willecke K., Eiberger J., Degen J., Eckardt D., Romualdi A., Guldenagel M., Deutsch U., Sohl G. Structural and functional diversity of connexin genes in the mouse and human genome. Biol. Chem. 2002, 383:725-737.
17. Araya R., Eckardt D., Maxeiner S., Krüger O., Theis M., Willecke K., Saez J.C. Expression of connexins during differentiation and regeneration of skeletal muscle: functional relevance of connexin43. J. Cell Sci. 2005, 118:27-37.
18. von Maltzahn J., Euwens C., Willecke K., Söhl G. The novel mouse connexin39 gene is expressed in developing striated muscle fibers. J. Cell Sci. 2004, 117:5381-5392.
19. Belluardo N., Trovato-Salinaro A., Mudo G., Condorelli D.F. Expression of the rat connexin 39 (rCx39) gene in myoblasts and myotubes in developing and regenerating skeletal muscles: an in situ hybridization study. Cell Tissue Res. 2005, 320:299-310.
20. Trovato-Salinaro A., Belluardo N., Frinchi M., von Maltzahn J., Willecke K., Condorelli D.F., Mudo G. Regulation of connexin gene expression during skeletal muscle regeneration in the adult rat. Am. J. Physiol. 2009, 296:C593-C606.
21. Reinecke H., Minami E., Virag J.I., Murry C.E. Gene transfer of connexin43 into skeletal muscle. Hum. Gene Ther. 2004, 15:627-636.
22. Araya R., Eckardt D., Riquelme M.A., Willecke K., Saez J.C. Presence and importance of connexin43 during myogenesis. Cell Commun. Adhes. 2003, 10:451-456.
23. Saez J.C., Berthoud V.M., Branes M.C., Martinez A.D., Beyer E.C. Plasma membrane channels formed by connexins: their regulation and functions. Physiol. Rev. 2003, 83:1359-1400.
24. Rodriguez C.I., Buchholz F., Galloway J., Sequerra R., Kasper J., Ayala R., Stewart A.F., Dymecki S.M. High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP. Nat. Genet. 2000, 25:139-140.
25. Magin T.M., McWhir J., Melton D.W. A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency. Nucleic Acids Res. 1992, 20:3795-3796.
26. Theis M., Magin T.M., Plum A., Willecke K. General or cell type-specific deletion and replacement of connexin-coding DNA in the mouse. Methods (San Diego, Calif) 2000, 20:205-218.
27. Traub O., Eckert R., Lichtenberg-Frate H., Elfgang C., Bastide B., Scheidtmann K.H., Hülser D.F., Willecke K. Immunochemical and electrophysiological characterization of murine connexin40 and -43 in mouse tissues and transfected human cells. Eur. J. Cell Biol. 1994, 64:101-112.
28. von Maltzahn J., Wulf V., Willecke K. Spatiotemporal expression of connexin 39 and -43 during myoblast differentiation in cultured cells and in the mouse embryo. Cell Commun. Adhes. 2006, 13:55-60.
29. Dahl E., Winterhager E., Traub O., Willecke K. Expression of gap junction genes, connexin40 and connexin43, during fetal mouse development. Anat. Embryol. 1995, 191:267-278.
30. Ling Y., Appelt D., Kelly A.M., Franzini-Armstrong C. Differences in the histogenesis of EDL and diaphragm in rat. Dev. Dyn. 1992, 193:359-369.
31. Elfgang C., Eckert R., Lichtenberg-Frate H., Butterweck A., Traub O., Klein R.A., Hülser D.F., Willecke K. Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells. J. Cell Biol. 1995, 129:805-817.
32. Bedner P., Niessen H., Odermatt B., Kretz M., Willecke K., Harz H. Selective permeability of different connexin channels to the second messenger cyclic AMP. J. Biol. Chem. 2006, 281:6673-6681.
33. Proulx A., Merrifield P.A., Naus C.C. Blocking gap junctional intercellular communication in myoblasts inhibits myogenin and MRF4 expression. Dev. Genet. 1997, 20:133-144.
34. Constantin B., Cognard C., Raymond G. Myoblast fusion requires cytosolic calcium elevation but not activation of voltage-dependent calcium channels. Cell Calcium 1996, 19:365-374.
35. Harris A., Locke D. Permeability of connexin channels 2009, 165-206. Humana Press, Springer. Connexins (Ed.).
36. Delling U., Tureckova J., Lim H.W., De Windt L.J., Rotwein P., Molkentin J.D. A calcineurin-NFATc3-dependent pathway regulates skeletal muscle differentiation and slow myosin heavy-chain expression. Mol. Cell. Biol. 2000, 20:6600-6611.
37. Porter G.A., Makuck R.F., Rivkees S.A. Reduction in intracellular calcium levels inhibits myoblast differentiation. J. Biol. Chem. 2002, 277:28942-28947.
38. Friday B.B., Mitchell P.O., Kegley K.M., Pavlath G.K. Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD. Differentiation Res. Biol. Diversity 2003, 71:217-227.
39. Tidball J.G. Inflammatory cell response to acute muscle injury. Med. Sci. Sports Exerc. 1995, 27:1022-1032.
40. Orimo S., Hiyamuta E., Arahata K., Sugita H. Analysis of inflammatory cells and complement C3 in bupivacaine-induced myonecrosis. Muscle Nerve 1991, 14:515-520.
41. Tidball J.G., Berchenko E., Frenette J. Macrophage invasion does not contribute to muscle membrane injury during inflammation. J. Leukoc. Biol. 1999, 65:492-498.
42. Weigert A., Weis N., Brune B. Regulation of macrophage function by sphingosine-1-phosphate. Immunobiology 2009, 214:748-760.
43. Squecco R., Sassoli C., Nuti F., Martinesi M., Chellini F., Nosi D., Zecchi-Orlandini S., Francini F., Formigli L., Meacci E. Sphingosine 1-phosphate induces myoblast differentiation through Cx43 protein expression: a role for a gap junction-dependent and -independent function. Mol. Biol. Cell 2006, 17:4896-4910.