Improved facial nerve identification with novel fluorescently labeled probe

Laryngoscope

Volumn 121, Issue 4, 2011, Pages 805-810

  Wu, Amy P ^a   Whitney, Michael A ^b   Crisp, Jessica L ^c   Friedman, Beth ^b   Tsien, Roger Y ^d   Nguyen, Quyen T ^a,c  

^a Division of Otolaryngology Head and Neck Surgery   (United States)

^b Department of Pharmacology ^*  (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

anastomosis; Facial nerve injury; fluorescent microscopy; nerve labeling.

Indexed keywords

F NP41; FLUORESCENT DYE; UNCLASSIFIED DRUG;

ANASTOMOSIS; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CONVALESCENCE; FACIAL NERVE; FACIAL NERVE SURGERY; FLUORESCENCE MICROSCOPY; NONHUMAN; OPERATION DURATION; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL;

ANASTOMOSIS, SURGICAL; ANIMALS; ANTIGENS, THY-1; BACTERIAL PROTEINS; FACIAL NERVE; FACIAL NERVE INJURIES; FLUORESCEINS; FLUORESCENT DYES; LUMINESCENT PROTEINS; MICE; MICE, TRANSGENIC; MICROSCOPY, FLUORESCENCE; NERVE DEGENERATION; NERVE REGENERATION; PEPTIDE LIBRARY; PEPTIDES;

EID: 79953068119     PISSN: 0023852X     EISSN: None     Source Type: Journal    
DOI: 10.1002/lary.21411     Document Type: Article

References (12)

1. Danner CJ., Facial nerve paralysis. Otolaryngol Clin N Am 2008; 41; 619-632. (Pubitemid 351626091)
2. Barr DM., Facial nerve trauma: optimal timing for repair. Laryngoscope 1991; 101: 835-848.
3. Humphrey CD, Kriet JD., Nerve repair and cable grafting for facial paralysis. Facial Plast Surg 2008; 24: 170-176. (Pubitemid 351717350)
4. Choi D, Dunn LT., Facial nerve repair and regeneration: an overview of basic principles for neurosurgeons. Acta Neurochir 2001; 143: 107-114.
5. Whitney MA, Crisp JL, Nguyen LT, et al. Fluorescent peptides can highlight peripheral nerves during surgery. Nature Biotechnology, advance online publication Feb 6, 2011 (DOI:10.1038/nbt.1764).
6. Feng G, Mellor RH, Bernstein M, et al. Imaging neuronal subsets in transgenic mice expressing multiple spectral variants of GFP. Neuron 2000; 28: 41-51.
7. Hadlock TA, Heaton J, Cheney M, Mackinnon SE., Functional recovery after facial and sciatic nerve crush injury in the rat. Arch Facial Plast Surg 2005; 7: 17-20. (Pubitemid 43973836)
8. Heaton JT, Kowaleski J, Edwards C, Smitson C, Hadlock TA., Evidence for facial nerve-independent mechanisms of blinking in the rat. Invest Ophthalmol Vis Sci 2010; 51: 179-182.
9. Kobbert C, Apps R, Bechmann I, Laciego JL, Mey J, Thanos S., Current concepts in neuroanatomical tracing. Prog Neurobiol 2000; 62: 327-351. (Pubitemid 30336472)
10. Richmond FJR, Gladdy R, Creasy JL, Ktamura S, Smits E, Thomson DB., Efficacy of seven retrograde tracers, compared in multiple-labelling studies of feline motoneurones. J Neurosci Methods 1994; 53: 35-46. (Pubitemid 24238749)
11. Marangos N, Illing R, Kruger J, Laszig R., In vivo visualization of the cochlear nerve and nuclei with fluorescent axonal tracers. Hear Res 2001; 162: 48-52. (Pubitemid 33070306)
12. O'Malley M, Wittkopf J, Cutler J, Labadie R, Hackett T, Haynes D., Fluorescent retrograde axonal tracing of the facial nerve. Laryngoscope 2006; 116: 1792-1797. (Pubitemid 44511363)