No association of PGRN 3'UTR rs5848 in frontotemporal lobar degeneration

Neurobiology of Aging

Volumn 32, Issue 4, 2011, Pages 754-755

  Rollinson, Sara ^a   Rohrer, Jonathan D ^b   van der Zee, Julie ^c   Sleegers, Kristel ^c   Mead, Simon ^b   Engelborghs, Sebastiaan ^d,e   Collinge, John ^b   De Deyn, Peter P ^d,e   Mann, David M A ^f   Van Broeckhoven, Christine ^c   Pickering Brown, Stuart M ^a  

^a UNIVERSITY OF MANCHESTER   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d UNIVERSITY OF ANTWERP   (Belgium)

^e Memory Clinic and Department of Neurology   (Belgium)

^f UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Frontotemporal lobar degeneration; PGRN; Progranulin; Rs5848; TDP 43

Indexed keywords

3' UNTRANSLATED REGION; ARTICLE; COHORT ANALYSIS; CONTROLLED STUDY; FRONTOTEMPORAL DEMENTIA; GENE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; PGRN GENE; PRIORITY JOURNAL; RISK ASSESSMENT;

3' UNTRANSLATED REGIONS; ALLELES; FRONTOTEMPORAL LOBAR DEGENERATION; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 79953058497     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2009.04.009     Document Type: Article

References (2)

1. Baker M., Mackenzie I.R., Pickering-Brown S.M., Gass J., Rademakers R., Lindholm C., Snowden J., Adamson J., Sadovnick A.D., Rollinson S., Cannon A., Dwosh E., Neary D., Melquist S., Richardson A., Dickson D., Berger Z., Eriksen J., Robinson T., Zehr C., Dickey C.A., Crook R., McGowan E., Mann D., Boeve B., Feldman H., Hutton M. Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. Nature 2006, 442:916-919.
2. Rademakers R., Eriksen J.L., Baker M., Robinson T., Ahmed Z., Lincoln S.J., Finch N., Rutherford N.J., Crook R.J., Josephs K.A., Boeve B.F., Knopman D.S., Petersen R.C., Parisi J.E., Caselli R.J., Wszolek Z.K., Uitti R.J., Feldman H., Hutton M.L., Mackenzie I.R., Graff-Radford N.R., Dickson D.W. Common variation in the miR-659 binding-site of GRN is a major risk factor for TDP43-positive frontotemporal dementia. Hum. Mol. Genet. 2008, 17:3631-3642.