The effect of intraperitoneally administered dimethyl sulfoxide on absence-like epileptic activity of freely moving WAG/Rij rats

Journal of Neuroscience Methods

Volumn 197, Issue 1, 2011, Pages 133-136

  Kovács, Zsolt ^a   Czurkó, András ^b,c   Kékesi, Katalin A ^b   Juhász, Gábor ^b  

^a UNIVERSITY OF WEST HUNGARY   (Hungary)

^b EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^c UNIVERSITY OF SZEGED   (Hungary)

Author keywords

Absence epilepsy; DMSO; WAG Rij rats

Indexed keywords

DIMETHYL SULFOXIDE;

ABSENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; ELECTROENCEPHALOGRAM; EPILEPTIC DISCHARGE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPIKE WAVE; WISTAR ALBINO GLAXO RAT;

ACTION POTENTIALS; ANIMALS; DIMETHYL SULFOXIDE; DISEASE MODELS, ANIMAL; EPILEPSY, ABSENCE; MALE; MOVEMENT; NEURONS; RATS; RATS, INBRED STRAINS;

EID: 79953055776     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2011.02.005     Document Type: Article

References (15)

1. Bauwens D., Hantson P., Laterre P.F., Michaux L., Latinne D., De Tourtchaninoff M., et al. Recurrent seizure and sustained encephalopathy associated with dimethylsulfoxide-preserved stem cell infusion. Leuk Lymphoma 2005, 46:1671-1674.
2. Coenen A.M., Van Luijtelaar E.L. Genetic animal models for absence epilepsy: a review of the WAG/Rij strain of rats. Behav Genet 2003, 33:635-655.
3. + current in rat hippocampal neurons. Brain Res 2001, 920:27-31.
4. Gurtovenko A.A., Anwar J. Modulating the structure and properties of cell membranes: the molecular mechanism of action of dimethyl sulfoxide. J Phys Chem B 2007, 111:10453-10460.
5. Hanslick J.L., Lau K., Noguchi K.K., Olney J.W., Zorumski C.F., Mennerick S., et al. Dimethyl sulfoxide (DMSO) produces widespread apoptosis in the developing central nervous system. Neurobiol Dis 2009, 34:1-10.
6. Jacob S.W., de la Torre J.C. Pharmacology of dimethyl sulfoxide in cardiac and CNS damage. Pharmacol Rep 2009, 61:225-235.
7. Kovács Z., Kékesi K.A., Szilágyi N., Abrahám I., Székács D., Király N., et al. Facilitation of spike-wave discharge activity by lipopolysaccharides in Wistar Albino Glaxo/Rijswijk rats. Neuroscience 2006, 140:731-742.
8. Kovács Z., Puskás L., Nyitrai G., Papp E., Császár I., Juhász G., et al. Suppression of spike-wave discharge activity and c-fos expression by 2-methyl-4-oxo-3H-quinazoline-3-acetyl piperidine (Q5) in vivo. Neurosci Lett 2007, 423:73-77.
9. Larsen J., Gasser K., Hahin R. An analysis of dimethylsulfoxide-induced action potential block: a comparative study of DMSO and other aliphatic water soluble solutes. Toxicol Appl Pharmacol 1996, 140:296-314.
10. Maclennan K., Smith P.F., Darlington C.L. The effects of ginkgolide B (BN52021) on guinea pig vestibular nucleus neurons in vitro: importance of controlling for effects of dimethylsulphoxide (DMSO) vehicles. Neurosci Res 1996, 26:395-399.
11. Marcacci G., Corazzelli G., Becchimanzi C., Arcamone M., Capobianco G., Russo F., et al. DMSO-associated encephalopathy during autologous peripheral stem cell infusion: a predisposing role of preconditioning exposure to CNS-penetrating agents?. Bone Marrow Transplant 2009, 44:133-135.
12. Paxinos G., Watson C. The rat brain stereotaxic coordinates 1997, Academic Press, Orlando.
13. Santos N.C., Figueira-Coelho J., Martins-Silva J., Saldanha C. Multidisciplinary utilization of dimethyl sulfoxide: pharmacological, cellular, and molecular aspects. Biochem Pharmacol 2003, 65:1035-1041.
14. Snead O.C. Basic mechanisms of generalized absence seizures. Ann Neurol 1995, 37:146-157.
15. Wong P.T., Tan S.F., Lee H.S. N-demethylation of methyl and dimethyl derivatives of phenytoin and their anticonvulsant activities in mice. Jpn J Pharmacol 1988, 48:473-478.