-
1
-
-
76249085581
-
Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: systematic review and meta-analysis
-
Beyenburg S., Stavem K., Schmidt D. Placebo-corrected efficacy of modern antiepileptic drugs for refractory epilepsy: systematic review and meta-analysis. Epilepsia 2010, 51:7-26.
-
(2010)
Epilepsia
, vol.51
, pp. 7-26
-
-
Beyenburg, S.1
Stavem, K.2
Schmidt, D.3
-
2
-
-
0031836237
-
Fatal toxicity of drugs used in the treatment of psychotic illnesses
-
Buckley N., McManus P. Fatal toxicity of drugs used in the treatment of psychotic illnesses. Br. J. Psychiatr. 1998, 172:461-464.
-
(1998)
Br. J. Psychiatr.
, vol.172
, pp. 461-464
-
-
Buckley, N.1
McManus, P.2
-
3
-
-
0027361997
-
Comparative behavioral and neurochemical activities of cholinergic antagonists in rats
-
Bymaster F.P., Heath I., Hendrix J.C., Shannon H.E. Comparative behavioral and neurochemical activities of cholinergic antagonists in rats. J. Pharmacol. Exp. Ther. 1993, 267:16-24.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.267
, pp. 16-24
-
-
Bymaster, F.P.1
Heath, I.2
Hendrix, J.C.3
Shannon, H.E.4
-
4
-
-
70549100017
-
Influence of orphenadrine upon the protective activity of various antiepileptics in the maximal electroshock-induced convulsions in mice
-
Czuczwar M., Cieszczyk J., Czuczwar K., Kis J., Saran T., Turski W.A. Influence of orphenadrine upon the protective activity of various antiepileptics in the maximal electroshock-induced convulsions in mice. Pharmacol. Rep. 2009, 61:732-736.
-
(2009)
Pharmacol. Rep.
, vol.61
, pp. 732-736
-
-
Czuczwar, M.1
Cieszczyk, J.2
Czuczwar, K.3
Kis, J.4
Saran, T.5
Turski, W.A.6
-
5
-
-
61849100988
-
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine
-
Desaphy J.F., Dipalma A., De Bellis M., Costanza T., Gaudioso C., Delmas P., George A.L., Camerino D.C. Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine. Pain 2009, 142:225-235.
-
(2009)
Pain
, vol.142
, pp. 225-235
-
-
Desaphy, J.F.1
Dipalma, A.2
De Bellis, M.3
Costanza, T.4
Gaudioso, C.5
Delmas, P.6
George, A.L.7
Camerino, D.C.8
-
6
-
-
0032563178
-
Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy
-
Klitgaard H., Matagne A., Gobert J., Wulfert E. Evidence for a unique profile of levetiracetam in rodent models of seizures and epilepsy. Eur. J. Pharmacol. 1998, 353:191-206.
-
(1998)
Eur. J. Pharmacol.
, vol.353
, pp. 191-206
-
-
Klitgaard, H.1
Matagne, A.2
Gobert, J.3
Wulfert, E.4
-
7
-
-
0029417266
-
Orphenadrine is an uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist: binding and patch clamp studies
-
Kornhuber J., Parsons C.G., Hartmann S., Retz W., Kamolz S., Thome J., Riederer P. Orphenadrine is an uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist: binding and patch clamp studies. J. Neural Transm. Gen. Sect. 1995, 102:237-246.
-
(1995)
J. Neural Transm. Gen. Sect.
, vol.102
, pp. 237-246
-
-
Kornhuber, J.1
Parsons, C.G.2
Hartmann, S.3
Retz, W.4
Kamolz, S.5
Thome, J.6
Riederer, P.7
-
8
-
-
84951384024
-
A simplified method of evaluating dose-response experiments
-
Litchfield J.T., Wilcoxon F. A simplified method of evaluating dose-response experiments. J. Pharmacol. Exp. Ther. 1949, 96:99-113.
-
(1949)
J. Pharmacol. Exp. Ther.
, vol.96
, pp. 99-113
-
-
Litchfield, J.T.1
Wilcoxon, F.2
-
9
-
-
0017662268
-
Deaths after overdoses of orphenadrine
-
Millar W.M. Deaths after overdoses of orphenadrine. Lancet 1977, 2:566.
-
(1977)
Lancet
, vol.2
, pp. 566
-
-
Millar, W.M.1
-
10
-
-
70449720874
-
Does pilocarpine-induced epilepsy in adult rats require status epilepticus?
-
Navarro M.G., Bramanti P., Osculati F., Chakir A., Nicolato E., Marzola P., Sbarbati A., Fabene P.F. Does pilocarpine-induced epilepsy in adult rats require status epilepticus?. PLoS One 2009, 4:e5759.
-
(2009)
PLoS One
, vol.4
-
-
Navarro, M.G.1
Bramanti, P.2
Osculati, F.3
Chakir, A.4
Nicolato, E.5
Marzola, P.6
Sbarbati, A.7
Fabene, P.F.8
-
11
-
-
62149089242
-
The history of status epilepticus and its treatment
-
Neligan A., Shorvon S.D. The history of status epilepticus and its treatment. Epilepsia 2009, 50(Suppl. 3):56-68.
-
(2009)
Epilepsia
, vol.50
, Issue.SUPPL. 3
, pp. 56-68
-
-
Neligan, A.1
Shorvon, S.D.2
-
13
-
-
34547828792
-
Development of new antiepileptic drugs: challenges, incentives, and recent advances
-
Perucca E., French J., Bialer M. Development of new antiepileptic drugs: challenges, incentives, and recent advances. Lancet Neurol. 2007, 6:793-804.
-
(2007)
Lancet Neurol.
, vol.6
, pp. 793-804
-
-
Perucca, E.1
French, J.2
Bialer, M.3
-
14
-
-
0035115881
-
Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo
-
Pubill D, Verdaguer E., Canudas A.M., Sureda F.X., Escubedo E., Camarasa J., Pallas M., Camins A. Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo. Br. J. Pharmacol. 2001, 132:693-702.
-
(2001)
Br. J. Pharmacol.
, vol.132
, pp. 693-702
-
-
Pubill, D.1
Verdaguer, E.2
Canudas, A.M.3
Sureda, F.X.4
Escubedo, E.5
Camarasa, J.6
Pallas, M.7
Camins, A.8
-
15
-
-
0014282950
-
The concentrations of orphenadrine and its N-demethylated derivatives in rat brain, after intraperitoneal administration of orphenadrine and tofenacine
-
Roozemond R.C., Hespe W., Nauta W.T. The concentrations of orphenadrine and its N-demethylated derivatives in rat brain, after intraperitoneal administration of orphenadrine and tofenacine. Int. J. Neuropharmacol. 1968, 7:293-300.
-
(1968)
Int. J. Neuropharmacol.
, vol.7
, pp. 293-300
-
-
Roozemond, R.C.1
Hespe, W.2
Nauta, W.T.3
-
16
-
-
36448963090
-
Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656
-
Scholz E.P., Konrad F.M., Weiss D.L., Zitron E., Kiesecker C., Bloehs R., Kulzer M., Thomas D., Kathofer S., Bauer A., Maurer M.H., Seemann G., Katus H.A., Karle C.A. Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656. N. S. Arch. Pharmacol. 2007, 376:275-284.
-
(2007)
N. S. Arch. Pharmacol.
, vol.376
, pp. 275-284
-
-
Scholz, E.P.1
Konrad, F.M.2
Weiss, D.L.3
Zitron, E.4
Kiesecker, C.5
Bloehs, R.6
Kulzer, M.7
Thomas, D.8
Kathofer, S.9
Bauer, A.10
Maurer, M.H.11
Seemann, G.12
Katus, H.A.13
Karle, C.A.14
-
18
-
-
0347364701
-
Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop
-
Stables J.P., Bertram E., Dudek F.E., Holmes G., Mathern G., Pitkanen A., White H.S. Therapy discovery for pharmacoresistant epilepsy and for disease-modifying therapeutics: summary of the NIH/NINDS/AES models II workshop. Epilepsia 2003, 44:1472-1478.
-
(2003)
Epilepsia
, vol.44
, pp. 1472-1478
-
-
Stables, J.P.1
Bertram, E.2
Dudek, F.E.3
Holmes, G.4
Mathern, G.5
Pitkanen, A.6
White, H.S.7
-
19
-
-
0033055438
-
In vitro and in vivo protective effect of orphenadrine on glutamate neurotoxicity
-
Sureda F.X., Gabriel C., Pallas M., Adan J., Martinez J.M., Escubedo E., Camarasa J., Camins A. In vitro and in vivo protective effect of orphenadrine on glutamate neurotoxicity. Neuropharmacology 1999, 38:671-677.
-
(1999)
Neuropharmacology
, vol.38
, pp. 671-677
-
-
Sureda, F.X.1
Gabriel, C.2
Pallas, M.3
Adan, J.4
Martinez, J.M.5
Escubedo, E.6
Camarasa, J.7
Camins, A.8
-
20
-
-
0020545095
-
Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study
-
Turski W.A., Cavalheiro E.A., Schwarz M., Czuczwar S.J., Kleinrok Z., Turski L. Limbic seizures produced by pilocarpine in rats: behavioural, electroencephalographic and neuropathological study. Behav. Brain Res. 1983, 9:315-335.
-
(1983)
Behav. Brain Res.
, vol.9
, pp. 315-335
-
-
Turski, W.A.1
Cavalheiro, E.A.2
Schwarz, M.3
Czuczwar, S.J.4
Kleinrok, Z.5
Turski, L.6
-
21
-
-
0023802851
-
Response of status epilepticus induced by lithium and pilocarpine to treatment with diazepam
-
Walton N.Y., Treiman D.M. Response of status epilepticus induced by lithium and pilocarpine to treatment with diazepam. Exp. Neurol. 1988, 101:267-275.
-
(1988)
Exp. Neurol.
, vol.101
, pp. 267-275
-
-
Walton, N.Y.1
Treiman, D.M.2
-
22
-
-
0024437590
-
Phenobarbital treatment of status epilepticus in a rodent model
-
Walton N.Y., Treiman D.M. Phenobarbital treatment of status epilepticus in a rodent model. Epilepsy Res. 1989, 4:216-221.
-
(1989)
Epilepsy Res.
, vol.4
, pp. 216-221
-
-
Walton, N.Y.1
Treiman, D.M.2
-
23
-
-
0026767430
-
Valproic acid treatment of experimental status epilepticus
-
Walton N.Y., Treiman D.M. Valproic acid treatment of experimental status epilepticus. Epilepsy Res. 1992, 12:199-205.
-
(1992)
Epilepsy Res.
, vol.12
, pp. 199-205
-
-
Walton, N.Y.1
Treiman, D.M.2
|