Immunosuppressive therapy in children

Journal of the Indian Medical Association

Volumn 109, Issue 2, 2011, Pages 101-107

  Prasad, Rajniti ^a   Singh, Utpal Kant ^a,b   Mittal, Roopali ^a   Mishra, O P ^a  

^a BANARAS HINDU UNIVERSITY   (India)

^b Nalanda Medical College   (India)

Author keywords

Auto immune disease; Azathioprine; Corticosteroids; Immunosuppressant

Indexed keywords

ADALIMUMAB; ALPHA INTERFERON; AZATHIOPRINE; BASILIXIMAB; BETA INTERFERON; CYCLOPHOSPHAMIDE; CYCLOSPORIN; CYCLOSPORIN A; DACLIZUMAB; DACTINOMYCIN; ETANERCEPT; GLUCOCORTICOID; IMMUNOGLOBULIN; IMMUNOSUPPRESSIVE AGENT; INFLIXIMAB; LEFLUNOMIDE; LYMPHOCYTE ANTIBODY; MALONONITRILOAMIDE; MERCAPTOPURINE; METHOTREXATE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; OKT 3; PREDNISOLONE; RAPAMYCIN; RHESUS D ANTIBODY; TACROLIMUS; THYMOCYTE ANTIBODY; UNCLASSIFIED DRUG; UNINDEXED DRUG; VINCRISTINE;

ACUTE GLOMERULONEPHRITIS; ACUTE GRAFT REJECTION; ACUTE LYMPHOBLASTIC LEUKEMIA; ANEMIA; ANKYLOSING SPONDYLITIS; APLASTIC ANEMIA; ARTICLE; ASEPTIC MENINGITIS; AUTOIMMUNE DISEASE; AUTOIMMUNE HEMOLYTIC ANEMIA; BONE MARROW SUPPRESSION; CARDIAC GRAFT REJECTION; CARDIOTOXICITY; CATARACT; CHILDHOOD DISEASE; CHRONIC ACTIVE HEPATITIS; CORTICOSTEROID INDUCED OSTEOPOROSIS; CORTICOSTEROID THERAPY; CROHN DISEASE; CYTOKINE PRODUCTION; DERMATOMYOSITIS; DIARRHEA; DNA ALKYLATION; DRUG FEVER; DRUG HALF LIFE; DRUG HYPERSENSITIVITY; DRUG INDICATION; DRUG INDUCED CANCER; DRUG INDUCED HEADACHE; DRUG MEGADOSE; DRUG METABOLISM; DRUG POTENTIATION; ENTERITIS; EPISTAXIS; GASTROINTESTINAL SYMPTOM; GLUCOSE INTOLERANCE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HEMORRHAGIC CYSTITIS; HISTIOCYTIC LYMPHOMA; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPOTENSION; IDIOPATHIC THROMBOCYTOPENIC PURPURA; IMMUNE COMPLEX NEPHRITIS; IMMUNE RESPONSE; IMMUNOSUPPRESSIVE TREATMENT; INFECTION; INJECTION SITE DISCOMFORT; KIDNEY GRAFT REJECTION; LEUKOPENIA; LIVER GRAFT REJECTION; LOADING DRUG DOSE; LYMPHOPROLIFERATIVE DISEASE; MIXED TISSUE DISORDER; MUCOSA INFLAMMATION; MULTIPLE SCLEROSIS; NEOPLASM; NEPHRITIS; NEPHROBLASTOMA; NEPHROTIC SYNDROME; NEPHROTOXICITY; NEUROTOXICITY; NEWBORN HEMOLYTIC DISEASE; PSORIASIS; PSORIATIC ARTHRITIS; RECOMMENDED DRUG DOSE; RHABDOMYOSARCOMA; RHEUMATOID ARTHRITIS; RIGOR; SEPSIS; SERUM SICKNESS; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOCYTOPENIA; TREATMENT RESPONSE; TROPHOBLASTIC TUMOR; UNSPECIFIED SIDE EFFECT; URTICARIA; WEGENER GRANULOMATOSIS;

EID: 79953043203     PISSN: 00195847     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Travers P - Immunobiology: The Immune System in Health and Disease. 5th ed. New York: Garland Publishers, 2001: 732-40.
2. VanBuskirk AM, Pidwell DJ, Adams PW, Orosz CG - Transplantation immunology. JAMA 1997; 278: 1993-9.
3. Waldmann TA - Immunotherapy: past, present and future. Nature Med 2003; 9: 269-77.
4. Armstrong WV - Principles and practice of monitoring immunosuppressive drugs. J Lab Med 2002; 26: 27-36.
5. Sompayrac LM - How the Immune System Works. Boston: Blackwell Science, 1999: 111-9.
6. Atkison P, Joubert G, Barron A, Grant D, Paradis K, Seidman E, et al - Hypertrophic cardiomyopathy associated with tacrolimus in paediatric transplant patients. Lancet 1995; 345: 894-6.
7. Rhen T, Cidlowski JA - Antiinflammatory action of glucocorticoids -new mechanisms for old drugs. N Engl J Med 2005; 353: 1711-23.
8. Grailer A, Nichols J, Hullett D, Sollinger HW, Burlingham WJ - Inhibition of human B cell responses in vitro by RS-61443, cyclosporine A and DAB486 IL-2. Transplant Proc 1991; 23: 314-5.
9. Anstey A, Lear JT - Azathioprine: clinical pharmacology and current indications in autoimmune disorders. Biol Drugs 1998; 9: 33-47. (Pubitemid 28053763)
10. Pham PT, Peng A, Wilkinson AH - Cyclosporine and tacrolimus-associated thrombotic microangiopathy. Am J Kidney Dis 2000; 36: 844-50.
11. Liu J, Farmer JJ, Lane WS, Friedman J, Weissman I, Schreiber SL - Calcineurin is a common target of cyclophilincyclosporin A and FKBP-FK506 complexes. Cell 1991; 66: 807-15. (Pubitemid 121001714)
12. Wang SC, Jordan ML, Tweardy DJ, Wright J, Hoffman RA, Simmons RL - FK-506 inhibits proliferation and IL-4 messenger RNA production by a T-helper 2 cell line. J Surg Res 1992; 53: 199-202.
13. Andoh TF, Burdmann EA, Fransechini N, Houghton DC, Bennett WM - Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506. Kidney Int 1996; 50: 1110-7. (Pubitemid 26342799)
14. Francavilla A, Carr BI, Starzl TE, Azzarone A, Carrieri G, Zeng QH - Effects of rapamycin on cultured hepatocyte proliferation and gene expression. Hepatology 1992; 15: 871-7.
15. Poon M, Marx SO, Gallo R, Badimon JJ, Taubman MB, Marks AR - Rapamycin inhibits vascular smooth muscle cell migration. J Clin Invest 1996; 98: 2277-83. (Pubitemid 26394201)
16. Cao W, Mohacsi P, Shorthouse R, Pratt R, Morris RE - Effects of rapamycin on growth factor-stimulated vascular smooth muscle cell DNA synthesis: inhibition of basic fibroblast growth factor and platelet-derived growth factor action and antagonism of rapamycin by FK506. Transplantation 1995; 59: 390-5.
17. Charles J, Travers P, Walport M, Shlomchik M - The Immune System in Health and Disease. 5th ed. Edinburgh: Churchill Livingstone, 2001: 732-8.
18. Cao WW, Kao PN, Chao AC, Gardner P, Ng J, Morris RE - Mechanism of the antiproliferative action of leflunomide: A77 1726, the active metabolite of leflunomide, does not block T-cell receptor-mediated signal transduction but its antiproliferative effects are antagonized by pyrimidine nucleosides. J Heart Lung Transplant 1995; 14:1016-30.
19. Nair RV, Cao W, Morris RE - The antiproliferative effect of leflunomide on vascular smooth muscle cells in vitro is mediated by selective inhibition of pyrimidine biosynthesis. Transplant Proc 1996; 28: 3081-3.
20. Katz SM, Hong JC, Kahan BD - New immunosuppressive agents. Transplant Proc 2000; 32: 620-1.
21. Strom TB, Ettenger RB - Investigational immunosuppressants: biologics. In: Norman DJ, Suki WN, editors. Primer on Transplantation. New York: American Society of Transplant Physicians,1988: 113-22.
22. Nashan B, Moore R, Amlot P, Schmidt AG, Abeywickrama K, Soulillou JP - Randomised trial of basiliximab versus placebo for control of acute cellular rejection in renal allograft recipients: CHIB 201 International Study Group. Lancet 1997; 350: 1193-8. (Pubitemid 127445091)
23. Vincenti F, Kirkman R, Light S, Bumgardner G, Pescovitz M, Halloran P, et al - Interleukin-2-receptor blockade with daclizumab to prevent acute rejection in renal transplantation: Daclizumab Triple Therapy Study Group. N Engl J Med 1998; 338: 161-5. (Pubitemid 28041863)
24. Takaoka A, Hayakawa S, Yanai H - Integration of interferonalpha/ beta signalling to p53 responses in tumour suppression and antiviral defence. Nature 2003; 424: 516-23. (Pubitemid 36975769)
25. Fumero E - Immunosuppressive drugs as an adjuvant to HIV treatment. J Antimicrob Chemother 2004; 53: 415-7.