Detection of phentermine in hair samples from drug suspects

Forensic Science International

Volumn 207, Issue 1-3, 2011, Pages e5-

  Lee, Sooyeun ^a   Kim, Jihyun ^a   In, Sanghwan ^a   Choi, Hwakyung ^a   Chung, Heesun ^a   Chung, Kyu Hyuck ^b  

^a National Institute of Scientific Investigation   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Amphetamines; Hair analysis; Phentermine

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; 3,4 METHYLENEDIOXYMETHAMPHETAMINE; AMPHETAMINE; HYDROCHLORIC ACID; METHAMPHETAMINE; METHANOL; PHENTERMINE; TRIFLUOROACETIC ANHYDRIDE;

ADULT; ARTICLE; CONCENTRATION (PARAMETERS); DERIVATIZATION; DRUG ABUSE; FEMALE; GAS CHROMATOGRAPHY; HAIR ANALYSIS; HUMAN; MALE; MASS SPECTROMETRY; PRIORITY JOURNAL;

EID: 79953034084     PISSN: 03790738     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.forsciint.2010.11.004     Document Type: Article

References (14)

1. Kaplan L.M. Pharmacological therapies for obesity. Gastroenterol. Clin. North Am. 2005, 34:91-104.
2. Colman E. Anorectics on trial: a half century of federal regulation of prescription appetite suppressants. Ann. Intern. Med. 2005, 143:380-385.
3. Brauer L.H., Johanson C.E., Schuster C.R., Rothman R.B., de Wit H. Evaluation of phentermine and fenfluramine, alone and in combination, in normal, healthy volunteers. Neuropsychopharmacology 1996, 14:233-241.
4. Rothman R.B., Blough B.E., Baumann M.H. Dopamine/serotonin releasers as medications for stimulant addictions. Prog. Brain Res. 2008, 172:385-406.
5. Kim K.K., Cho H.J., Kang H.C., Youn B.B., Lee K.R. Effects on weight reduction, and safety of short-term phentermine administration in Korean obese people. Yonsei Med. J. 2006, 47:614-625.
6. Baselt R.C. Disposition of Toxic Drugs and Chemicals in Man 2000, Chemical Toxicology Institute, Forster City, CA, pp. 694-696. fifth edition.
7. Hendricks E.J., Greenway F.L. A study of abrupt phentermine cessation in patients in a weight management program. Am. J. Ther. 2010, March 2. [Epub ahead of print].
8. (accessed 11.11.10). http://www.justice.gov/dea/pubs/scheduling.html.
9. Lee S., Han E., Park Y., Choi H., Chung H. Distribution of methamphetamine and amphetamine in drug abusers' head hair. Forensic Sci. Int. 2009, 190:16-18.
10. Han E., Lee S., Lee J., Back S., Kim D., Woo S., Kim C., Park Y., Lim M., Chung H. Simultaneous analysis of amphetamine type stimulants in hair by GC/MS. Annu. Rep. N.I.S.I. 2007, 39:240-249.
11. Couper F.J., Pemberton M., Jarvis A., Hughes M., Logan B.K. Prevalence of drug use in commercial tractor-trailer drivers. J. Forensic Sci. 2002, 47:562-567.
12. Kim J.Y., Jung K.S., Kim M.K., Lee J.I., In M.K. Simultaneous determination of psychotropic phenylalkylamine derivatives in human hair by gas chromatography/mass spectrometry. Rapid Commun. Mass Spectrom. 2007, 21:1705-1720.
13. Huang W.H., Liu C.H., Liu R.H., Tseng Y.L. Confirming urinary excretion of mephentermine and phentermine following the ingestion of oxethazaine by gas chromatography-mass spectrometry analysis. J. Anal. Toxicol. 2010, 34:73-77.
14. Hsu M.C., Lin S.F., Kuan C.P., Chu W.L., Chan K.H., Chang-Chien G.P. Oxethazaine as the source of mephentermine and phentermine in athlete's urine. Forensic Sci. Int. 2009, 185:e1-e5.