Design and evaluation of flexible membrane vesicles (FMVs) for enhanced topical delivery of capsaicin

Journal of Drug Targeting

Volumn 19, Issue 4, 2011, Pages 293-302

  Raza, Kaisar ^a   Singh, Bhupinder ^a   Mahajan, Anadi ^a   Negi, Poonam ^a   Bhatia, Amit ^a   Katare, O P ^a  

^a PANJAB UNIVERSITY   (India)

Author keywords

edge activator; irritation; liposomes; pain; phospholipid; Transfersomes

Indexed keywords

CAPSAICIN; FLEXIBLE MEMBRANE VESICLE; LIPOSOME; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ARTICLE; BURNING SENSATION; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG PENETRATION; DRUG RETENTION; DRUG STABILITY; EVALUATION; HUMAN; HUMAN EXPERIMENT; HYDRATION; MOUSE; NANOENCAPSULATION; NONHUMAN; NORMAL HUMAN; PARTICLE SIZE; PRIORITY JOURNAL; PRURITUS; SKIN IRRITATION; SKIN PERMEABILITY; SKIN REDNESS; TAIL FLICK TEST;

ADMINISTRATION, TOPICAL; ANIMALS; CAPSAICIN; DOSAGE FORMS; DRUG STABILITY; LIPOSOMES; MICE; SENSORY SYSTEM AGENTS;

EID: 79953007356     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2010.499464     Document Type: Article

References (34)

1. Agarwal R, Katare OP, Vyas SP. (2001). Preparation and in vitro evaluation of liposomal/niosomal delivery systems for antipsoriatic drug dithranol. Int J Pharm, 228, 43-52. (Pubitemid 32905364)
2. Basha KM, Whitehouse FW. (1991). Capsaicin: a therapeutic option for painful diabetic neuropathy. Henry Ford Hosp Med J, 39, 138-140.
3. Bezrukova AG, Rozenberg OA. (1981). Determination of liposome parameters by the turbidity spectrum method. Biull Eksp Biol Med, 91, 506-508.
4. Bhatia A, Singh B, Rani V, Katare OP. (2007). Formulation, characterization, and evaluation of benzocaine phospholipid-tagged lipospheres for topical application. J Biomed Nanotechnol, 3, 81-89. (Pubitemid 351877131)
5. Cevc G. (1996). Transfersomes, liposomes and other lipid suspensions on the skin: permeation enhancement, vesicle penetration, and transdermal drug delivery. Crit Rev Ter Drug Carrier Syst, 13, 257-388. (Pubitemid 27024259)
6. Cevc G, Blume G. (2001). New, highly efcient formulation of diclofenac for the topical, transdermal administration in ultradeformable drug carriers, Transfersomes. Biochim Biophys Acta, 1514, 191-205. (Pubitemid 32831008)
7. Cevc G, Blume G, Schätzlein A. (1997). Transfersomes-mediated transepidermal delivery improves the regio-specifcity and biological activity of corticosteroids in vivo. J Control Rel, 45, 211-226.
8. Cevc G, Gebauer D, Stieber J, Schätzlein A, Blume G. (1998). Ultrafexible vesicles, Transfersomes, have an extremely low pore penetration resistance and transport therapeutic amounts of insulin across the intact mammalian skin. Biochim Biophys Acta, 1368, 201-215. (Pubitemid 28031874)
9. Daniel WW. (2008). Biostatistics. New York: John Wiley & Sons Inc
10. El Maghraby GM, Williams AC, Barry BW. (1999). Analysis Of Variance. Skin delivery of oestradiol from deformable and traditional liposomes: mechanistic studies. J Pharm Pharmacol, 51, 1123-1134. (Pubitemid 29520458)
11. El Maghraby GM, Williams AC, Barry BW. (2000). Oestradiol skin delivery from ultradeformable liposomes: refnement of surfactant concentration. Int J Pharm, 196, 63-74. (Pubitemid 30089515)
12. Fry DW, White JC, Goldman ID. (1978). Rapid separation of low molecular weight solutes from liposomes without dilution. Anal Biochem, 90, 809-815. (Pubitemid 9087732)
13. Grabielle-Madelmont C, Lesieur S, Ollivon M. (2003). Characterization of loaded liposomes by size exclusion chromatography. J Biochem Biophys Methods, 56, 189-217. (Pubitemid 36776602)
14. Hiruta Y Hattori Y Kawano K, Obata Y Maitani Y. (2006). Novel ultra-deformable vesicles entrapped with bleomycin and enhanced to penetrate rat skin. J Control Release, 113, 146-154. (Pubitemid 43928150)
15. Honeywell-Nguyen PL, Bouwstra JA. (2005). Vesicles as a tool for transdermal and dermal delivery. Drug Discov Today Technol, 2, 67-74. (Pubitemid 40946310)
16. Honeywell-Nguyen PL, de Graaf AM, Groenink HW, Bouwstra JA. (2002). Te in vivo and in vitro interactions of elastic and rigid vesicles with human skin. Biochim Biophys Acta, 1573, 130-140. (Pubitemid 35217934)
17. Honeywell-Nguyen PL, Wouter Groenink HW, de Graaf AM, Bouwstra JA. (2003). Te in vivo transport of elastic vesicles into human skin: efects of occlusion, volume and duration of application. J Control Release, 90, 243-255. (Pubitemid 36694967)
18. Jain S, Jain P, Umamaheshwari RB, Jain NK. (2003). Transfersomes-a novel vesicular carrier for enhanced transdermal delivery: development, characterization, and performance evaluation. Drug Dev Ind Pharm, 29, 1013-1026. (Pubitemid 37346103)
19. Jain SK, Jain RK, Chourasia MK, Jain AK, Chalasani KB, Soni V, Jain A. (2005). Design and development of multivesicular liposomal depot delivery system for controlled systemic delivery of acyclovir sodium. AAPS PharmSciTech, 6, E35-E41. (Pubitemid 41631003)
20. Knepp VM, Hinz RS, Jr Szoka FC, Guy RH. (1988). Controlled drug release from a novel liposomal delivery system. I: investigation of transdermal potential. J Control Rel, 5, 211-221. (Pubitemid 18038210)
21. Knepp VM, Jr Szoka FC, Guy RH. (1990). Controlled drug release from a novel liposomal delivery system. II: transdermal delivery characteristics. J Control Rel, 12, 25-30. (Pubitemid 20101608)
22. Kulkarni SK. (1999). Experiments on intact preparations (in vivo studies). Handbook of Experimental Pharmacology. Pitam Pura, New Delhi, India: Vallabh Parkashan.
23. Loan Honeywell-Nguyen P, Wouter Groenink HW, Bouwstra JA. (2006). Elastic vesicles as a tool for dermal and transdermal delivery. J Liposome Res, 16, 273-280. (Pubitemid 44359000)
24. Lynn B. (1990). Capsaicin: actions on nociceptive C-fbres and therapeutic potential. Pain, 41, 61-69. (Pubitemid 20152750)
25. Magnusson BM, Koskinen LD. (2000). In vitro percutaneous penetration of topically applied capsaicin in relation to in vivo sensation responses. Int J Pharm, 195, 55-62. (Pubitemid 30089490)
26. Monsereenusorn Y, Kongsamut S, Pezalla PD. (1982). Capsaicin-a literature survey. Crit Rev Toxicol, 10, 321-339.
27. Rains C, Bryson HM. (1995). Topical capsaicin. A review of its pharmacological properties and therapeutic potential in post-herpetic neuralgia, diabetic neuropathy and osteoarthritis. Drugs Aging, 7, 317-328.
28. Rao GU, Murthy R, Marfatia YS, Shankar R. (1993). Infuence of liposomal drug entrapment on the performance of corticosteroid creams. Indian J Dermatol Venereol Leprol, 59, 184-186. (Pubitemid 24084515)
29. Reynolds JA, Nozaki Y Tanford C (1983). Gel-exclusion chromatography on S1000 Sephacryl: application to phospholipid vesicles. Anal Biochem, 130, 471-474. (Pubitemid 13093595)
30. Simões SI, Tapadas JM, Marques CM, Cruz ME, Martins MB, Cevc G. (2005). Permeabilisation and solubilisation of soybean phosphatidylcholine bilayer vesicles, as membrane models, by polysorbate, Tween 80. Eur J Pharm Sci, 26, 307-317. (Pubitemid 41282799)
31. Singh B, Mehta G, Kumar R, Bhatia A, Ahuja N, Katare OP. (2005). Design, development and optimization of nimesulide-loaded liposomal systems for topical application. Curr Drug Deliv, 2, 143-153. (Pubitemid 40488624)
32. van den Bergh BA, Wertz PW, Junginger HE, Bouwstra JA. (2001). Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements. Int J Pharm, 217, 13-24. (Pubitemid 32268629)
33. Wang YY Hong CT, Chiu WT, Fang JY (2001). In vitro and in vivo evaluations of topically applied capsaicin and nonivamide from hydrogels. Int J Pharm, 224, 89-104.
34. Yosipovitch G, Maibach HI, Rowbotham MC. (1999). Efect of EMLA pre-treatment on capsaicin-induced burning and hyperalgesia. Acta Derm Venereol, 79, 118-121. (Pubitemid 29185305)