Slowly produced MicroRNAs control protein levels

Journal of Biological Chemistry

Volumn 286, Issue 6, 2011, Pages 4742-4748

  Whichard, Zakary L ^a   Motter, Adilson E ^b   Stein, Peter J ^a   Corey, Seth J ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEX FORMATIONS; CONTROL ELEMENTS; COPY NUMBER; DYNAMICAL MODEL; MECHANISTIC MODELS; METABOLIC DISORDERS; MICRORNAS; MODEL EQUATIONS; POST-TRANSCRIPTIONAL REGULATIONS; PROTEIN CONCENTRATIONS; PROTEIN DEGRADATION; PROTEIN LEVEL; PROTEIN SYNTHESIS; STATE VARIABLES; STEADY STATE SOLUTION; SYNTHESIS RATE; TARGET PROTEINS;

DEGRADATION; NUCLEIC ACIDS; SENSITIVITY ANALYSIS;

PROTEINS;

MESSENGER RNA; MICRORNA;

ARTICLE; CALCULATION; COMPLEX FORMATION; CONTROLLED STUDY; GENE DOSAGE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN PROCESSING; PROTEIN SYNTHESIS; PROTEIN TARGETING; RNA DEGRADATION; RNA SYNTHESIS; SENSITIVITY ANALYSIS; ANIMAL; BIOLOGICAL MODEL; BIOSYNTHESIS; HUMAN; INFLAMMATION; METABOLIC DISORDER; METABOLISM; NEOPLASM;

ANIMALS; HUMANS; INFLAMMATION; METABOLIC DISEASES; MICRORNAS; MODELS, BIOLOGICAL; NEOPLASMS; PROTEIN BIOSYNTHESIS; RNA, MESSENGER;

EID: 79952999220     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.166348     Document Type: Article

References (36)

1. Llave, C., Xie, Z., Kasschau, K. D., and Carrington, J. C. (2002) Science 297, 2053-2056
2. Lewis, B. P., Burge, C. B., and Bartel, D. P. (2005) Cell 120, 15-20
3. Bartel, D. P. (2004) Cell 116, 281-297
4. Chang, T. C., and Mendell, J. T. (2007) Annu. Rev. Genomics Hum. Genet. 8, 215-239
5. Calin, G. A., and Croce, C. M. (2006) Nat. Rev. Cancer 6, 857-866
6. Flynt, A. S., and Lai, E. C. (2008) Nat. Rev. Genet. 9, 831-842
7. Pfeffer, S., Zavolan, M., Grässer, F. A., Chien, M., Russo, J. J., Ju, J., John, B., Enright, A. J., Marks, D., Sander, C., and Tuschl, T. (2004) Science 304, 734-736
8. Hébert, S. S., and De Strooper, B. (2009) Trends Neurosci. 32, 199-206
9. Lynam-Lennon, N., Maher, S. G., and Reynolds, J. V. (2009) Biol. Rev. Camb. Philos. Soc. 84, 55-71
10. Filipowicz, W., Bhattacharyya, S. N., and Sonenberg, N. (2008) Nat. Rev. Genet. 9, 102-114
11. Levine, E., Ben Jacob, E., and Levine, H. (2007) Biophys. J. 93, L52-54
12. Xie, Z. R., Yang, H. T., Liu, W. C., and Hwang, M. J. (2007) Biochem. Biophys. Res. Commun. 358, 722-726
13. Nandi, A., Vaz, C., Bhattacharya, A., and Ramaswamy, R. (2009) BMC Systems Biology 3, 45
14. Levine, E., Zhang, Z., Kuhlman, T., and Hwa, T. (2007) PLos Biology 5, e229
15. Nissan, T., and Parker, R. (2008) RNA 14, 1480-1491
16. Pape, T., Wintermeyer, W., and Rodnina, M. V. (1998) EMBO J. 17, 7490-7497
17. Savelsbergh, A., Katunin, V. I., Mohr, D., Peske, F., Rodnina, M. V., and Wintermeyer, W. (2003) Mol. Cell 11, 1517-1523
18. Scherer, S. (2008) A Short Guide to the Human Genome, Cold Spring Harbor Laboratory Press, New York
19. Olofsson, S. O., Boström, K., Carlsson, P., Borén, J., Wettesten, M., Bjursell, G., Wiklund, O., and Bondjers, G. (1987) Am. Heart J. 113, 446-452
20. Altuvia, S. (2004) J. Bacteriol. 186, 6679-6680
21. Altuvia, S., and Wagner, E. G. (2000) Proc. Natl. Acad. Sci. U.S.A. 97, 9824-9826
22. Altuvia, S., Zhang, A., Argaman, L., Tiwari, A., and Storz, G. (1998) EMBO J. 17, 6069-6075
23. Chitnis, N., Hyman, J. M., and Cushing, J. M. (2008) Bull. Math Biol. 70, 1272-1296
24. Shimoni, Y., Friedlander, G., Hetzroni, G., Niv, G., Altuvia, S., Biham, O., and Margalit, H. (2007) Mol. Syst. Biol. 3, 138
25. Baek, D., Villén, J., Shin, C., Camargo, F. D., Gygi, S. P., and Bartel, D. P. (2008) Nature 455, 64-71
26. Selbach, M., Schwanhäusser, B., Thierfelder, N., Fang, Z., Khanin, R., and Rajewsky, N. (2008) Nature 455, 58-63
27. Clancy, J. L., Nousch, M., Humphreys, D. T., Westman, B. J., Beilharz, T. H., and Preiss, T. (2007) Methods Enzymol. 431, 83-111
28. Saltelli, A., Chan, K., and Scott, E. M. (2000) Sensitivity Analysis, John Wiley & Sons, Ltd., New York
29. Saltelli, A., Tarantola, S., and Chan, K. P. (1999) Technometrics 41, 39-56
30. Saltelli, A., and Annoni, P. (2010) Environmental Modelling and Software 25, 1508-1517
31. Kai, Z. S., and Pasquinelli, A. E. (2010) Nat. Struct. Mol. Biol. 17, 5-10
32. Costinean, S., Zanesi, N., Pekarsky, Y., Tili, E., Volinia, S., Heerema, N., and Croce, C. M. (2006) Proc. Natl. Acad. Sci. U.S.A. 103, 7024-7029
33. O'Connell, R. M., Rao, D. S., Chaudhuri, A. A., Boldin, M. P., Taganov, K. D., Nicoll, J., Paquette, R. L., and Baltimore, D. (2008) J. Exp. Med. 205, 585-594
34. Thai, T. H., Calado, D. P., Casola, S., Ansel, K. M., Xiao, C., Xue, Y., Murphy, A., Frendewey, D., Valenzuela, D., Kutok, J. L., Schmidt-Supprian, M., Rajewsky, N., Yancopoulos, G., Rao, A., and Rajewsky, K. (2007) Science 316, 604-608
35. Roush, S., and Slack, F. J. (2008) Trends Cell Biol. 18, 505-516
36. Segel, L., and Slemrod, M. (1989) SIAM Rev. 31, 446-477