Statins may increase intracerebral hemorrhage volume

Canadian Journal of Neurological Sciences

Volumn 37, Issue 6, 2010, Pages 791-796

  Ricard, Geneviève ^b,c   Garant, Marie Pierre ^a,b   Carrier, Nathalie ^a,b   Leblanc, Nancy ^d   Boulanger, Jean Martin ^c,d  

^a Centre Hospitalier Universitaire de Sherbrooke   (Canada)

^b CENTRE HOSPITALIER UNIVERSITAIRE DE SHERBROOKE   (Canada)

^c UNIVERSITÉ DE SHERBROOKE   (Canada)

^d HÔPITAL CHARLES LEMOYNE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; ATORVASTATIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PRAVASTATIN; SIMVASTATIN;

ADULT; AGED; ANTICOAGULANT THERAPY; ARTICLE; BRAIN HEMATOMA; BRAIN HEMORRHAGE; BRAIN ISCHEMIA; COMORBIDITY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CRANIOTOMY; DIABETES MELLITUS; DISEASE COURSE; DRUG USE; FEMALE; HEART DISEASE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL;

EID: 79952982758     PISSN: 03171671     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0317167100051453     Document Type: Article

References (23)

1. Yano K, Reed DM, MacLean CJ. Serum cholesterol and hemorrhagic stroke in the Honolulu heart program. Stroke. 1989; 20:1460-5. (Pubitemid 19278129)
2. Zhang X, Patel A, Horibe H, et al. Cholesterol, coronary heart disease, and stroke in the Asia Pacific region. Int J Epidemiol. 2003;32:563-72. (Pubitemid 37039010)
3. Iso H, Jacobs DR Jr., Wentworth D, et al. Serum cholesterol levels and six-year mortality from stroke in 350, 977 men screened for the multiple risk factor intervention trial. N Engl J Med. 1989; 320:904-10. (Pubitemid 19101595)
4. Mosheimer BA, Kaneider NC, Feistritzer C, et al. Cd40-liganddependent induction of cox-2 gene expression in endothelial cells by activated platelets: Inhibitory effects of atorvastatin. Blood Coagul Fibrinolysis. 2005;16:105-10. (Pubitemid 40418588)
5. Serebruany VL, Miller M, Pokov AN, et al. Effect of statins on platelet par-1 thrombin receptor in patients with the metabolic syndrome (from the par-1 inhibition by statins [Paris] study). Am J Cardiol. 2006;97:1332-6.
6. Kahn ML, Nakanishi-Matsui M, Shapiro MJ, et al. Proteaseactivated receptors 1 and 4 mediate activation of human platelets by thrombin. J Clin Invest. 1999;103:879-88.
7. Goldstein LB, Amarenco P, Szarek M, et al. Hemorrhagic stroke in the stroke prevention by aggressive reduction in cholesterol levels study. Neurology. 2008;70:2364-70.
8. Collins R, Armitage J, Parish S, et al. Effects of cholesterollowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions. Lancet. 2004;363:757-67.
9. Vergouwen MD, de Haan RJ, Vermeulen M, et al. Statin treatment and the occurrence of hemorrhagic stroke in patients with a history of cerebrovascular disease.[see comment]. Stroke. 2008; 39:497-502. (Pubitemid 351619482)
10. Baigent C, Keech A, Kearney PM, et al. Efficacy and safety of cholesterol-lowering treatment: Prospective meta-analysis of data from 90, 056 participants in 14 randomised trials of statins. Lancet. 2005;366:1267-78.
11. Kasner SE, Cucchiara BL, McGarvey ML, et al. Modified National Institutes of Health Stroke Scale can be estimated from medical records. Stroke. 2003;34:568-70. (Pubitemid 36206366)
12. Kothari RU, Brott T, Broderick JP, et al. The ABCs of measuring intracerebral hemorrhage volumes. Stroke. 1996;27:1304-5. (Pubitemid 26286157)
13. Amarenco P, Bogousslavsky J, Callahan A 3rd, et al. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med. 2006;355:549-59. (Pubitemid 44202151)
14. Reed DM. The paradox of high risk of stroke in populations with low risk of coronary heart disease. Am J Epidemiol. 1990;131: 579-88. (Pubitemid 20137226)
15. Bang OY, Saver JL, Liebeskind DS, et al. Cholesterol level and symptomatic hemorrhagic transformation after ischemic stroke thrombolysis. Neurology. 2007;68:737-42. (Pubitemid 46667898)
16. Kim BJ, Lee SH, Ryu WS, et al. Low level of low-density lipoprotein cholesterol increases hemorrhagic transformation in large artery atherothrombosis but not in cardioembolism. Stroke. 2009;40:1627-32.
17. Ramirez-Moreno JM, Casado-Naranjo I, Portilla JC, et al. Serum cholesterol LDL and 90-day mortality in patients with intracerebral hemorrhage. Stroke. 2009;40:1917-20.
18. Seyfried D, Han Y, Lu D, et al. Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats. J Neurosurg. 2004;101:104-7. (Pubitemid 38808468)
19. Naval NS, Abdelhak TA, Zeballos P, et al. Prior statin use reduces mortality in intracerebral hemorrhage. [see comment]. Neurocrit Care. 2008;8:6-12 (Pubitemid 351378099)
20. Leker RR, Khoury ST, Rafaeli G, et al. Prior use of statins improves outcome in patients with intracerebral hemorrhage. Prospective data from the national acute stroke Israeli surveys (NASIS). Stroke. 2009;40:2581-4.
21. Fitz Maurice E, Wendell L, Snider R, et al. Effect of statins on intracerebral hemorrhage outcome and recurrence. Stroke. 2008; 39:2151-4.
22. Meier N, Nedeltchev K, Brekenfeld C, et al. Prior statin use, intracranial hemorrhage, and outcome after intra-arterial thrombolysis for acute ischemic stroke. Stroke. 2009;40: 1729-37.
23. Amarenco P, Labreuch J. Lipid management in the prevention of stroke: review and updated meta-analysis of statins for stroke prevention. Lancet Neurol. 2009;8;453-63.