메뉴 건너뛰기




Volumn 3, Issue 1, 2011, Pages 37-46

A cost-effectiveness analysis of different therapies in patients with chronic hepatitis B in Italy

Author keywords

Adefovir; Chronic hepatitis B; Cost effectiveness; Entecavir; Lamivudine; Markov model; Pegylated interferon; Telbivudine; Tenofovir

Indexed keywords

ADEFOVIR; ENTECAVIR; HEPATITIS B(E) ANTIGEN; LAMIVUDINE; PEGINTERFERON; TELBIVUDINE; TENOFOVIR;

EID: 79952977384     PISSN: None     EISSN: 11786981     Source Type: Journal    
DOI: 10.2147/CEOR.S16655     Document Type: Review
Times cited : (19)

References (59)
  • 1
    • 58149296156 scopus 로고    scopus 로고
    • EASL clinical practice guidelines: Management of chronic hepatitis B
    • European Association for the Study of the Liver
    • European Association for the Study of the Liver. EASL clinical practice guidelines: management of chronic hepatitis B. J Hepatol. 2009;50(2): 227-242.
    • (2009) J Hepatol , vol.50 , Issue.2 , pp. 227-242
  • 2
    • 54849146600 scopus 로고    scopus 로고
    • Hepatitis B virus infection
    • Dienstag JL. Hepatitis B virus infection. N Engl J Med. 2008;359(14): 1486-1500.
    • (2008) N Engl J Med , vol.359 , Issue.14 , pp. 1486-1500
    • Dienstag, J.L.1
  • 3
    • 73849138259 scopus 로고    scopus 로고
    • Monotherapy versus combination therapy for the treatment of chronic hepatitis B
    • Carey I, Harrison PM. Monotherapy versus combination therapy for the treatment of chronic hepatitis B. Expert Opin Investig Drugs. 2009; 18(11):1655-1666.
    • (2009) Expert Opin Investig Drugs , vol.18 , Issue.11 , pp. 1655-1666
    • Carey, I.1    Harrison, P.M.2
  • 4
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • BEHoLD AI463022 Study Group
    • Chang TT, Gish RG, de Man R, et al; BEHoLD AI463022 Study Group. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med. 2006;354(10):1001-1010.
    • (2006) N Engl J Med , vol.354 , Issue.10 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3
  • 5
    • 57349095400 scopus 로고    scopus 로고
    • Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B
    • Marcellin P, Heathcote EJ, Buti M, et al. Tenofovir disoproxil fumarate versus adefovir dipivoxil for chronic hepatitis B. N Engl J Med. 2008; 359(23):2442-2455.
    • (2008) N Engl J Med , vol.359 , Issue.23 , pp. 2442-2455
    • Marcellin, P.1    Heathcote, E.J.2    Buti, M.3
  • 6
    • 77957331059 scopus 로고    scopus 로고
    • Tenofovir and entecavir are the most effective antiviral agents for chronic hepatitis B: A systematic review and Bayesian meta-analyses
    • [Epub ahead of print]
    • Woo G, Tomlinson G, Nishikawa Y, et al. Tenofovir and entecavir are the most effective antiviral agents for chronic hepatitis B: a systematic review and Bayesian meta-analyses. Gastroenterology. 2010 [Epub ahead of print].
    • (2010) Gastroenterology
    • Woo, G.1    Tomlinson, G.2    Nishikawa, Y.3
  • 7
    • 74949135174 scopus 로고    scopus 로고
    • A significant proportion of patients with chronic hepatitis B who are candidates for antiviral treatment are untreated: A region-wide survey in Italy
    • Ligurian Hepatitis B Virus Study Group
    • Giannini EG, Torre F, Basso M, et al; Ligurian Hepatitis B Virus Study Group. A significant proportion of patients with chronic hepatitis B who are candidates for antiviral treatment are untreated: a region-wide survey in Italy. J Clin Gastroenterol. 2009;43(10):1001-1007.
    • (2009) J Clin Gastroenterol , vol.43 , Issue.10 , pp. 1001-1007
    • Giannini, E.G.1    Torre, F.2    Basso, M.3
  • 8
    • 0348134677 scopus 로고    scopus 로고
    • Epidemiological and clinical burden of chronic hepatitis B virus/hepatitis C virus infection. A multicenter Italian study
    • Gaeta GB, Stornaiuolo G, Precone DF, et al. Epidemiological and clinical burden of chronic hepatitis B virus/hepatitis C virus infection. A multicenter Italian study. J Hepatol. 2003;39(6):1036-1041.
    • (2003) J Hepatol , vol.39 , Issue.6 , pp. 1036-1041
    • Gaeta, G.B.1    Stornaiuolo, G.2    Precone, D.F.3
  • 9
    • 40649105322 scopus 로고    scopus 로고
    • Estimating the future health burden of chronic hepatitis B and the impact of therapy in Spain
    • Idris BI, Brosa M, Richardus JH, et al. Estimating the future health burden of chronic hepatitis B and the impact of therapy in Spain. Eur J Gastroenterol Hepatol. 2008;20(4):320-326.
    • (2008) Eur J Gastroenterol Hepatol , vol.20 , Issue.4 , pp. 320-326
    • Idris, B.I.1    Brosa, M.2    Richardus, J.H.3
  • 10
    • 61749092750 scopus 로고    scopus 로고
    • Two year tenofovir disoproxil fumarate (TDF) treatment and adenofovir dipivoxil (ADV) switch data in HbeAg-positive patients with chronic hepatitis B (Study 103), preliminary analysis [Abstract]
    • Heathcote JE, Gane EJ, de Man A, et al. Two year tenofovir disoproxil fumarate (TDF) treatment and adenofovir dipivoxil (ADV) switch data in HbeAg-positive patients with chronic hepatitis B (Study 103), preliminary analysis [Abstract]. Hepatology. 2008;48 Suppl 4:309A.
    • (2008) Hepatology , vol.48 , Issue.SUPPL. 4
    • Heathcote, J.E.1    Gane, E.J.2    de Man, A.3
  • 11
    • 77950613329 scopus 로고    scopus 로고
    • Three years of tenofovir disoproxil (TDF) treatment in HbeAg-positive patients (HBeAg+) with chronic hepatitis B (Study 103), preliminary analysis [Abstract]
    • Heathcote JE, Gane EJ, de Man A, et al. Three years of tenofovir disoproxil (TDF) treatment in HbeAg-positive patients (HBeAg+) with chronic hepatitis B (Study 103), preliminary analysis [Abstract]. Hepatology. 2009;50 Suppl 4:533A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL. 4
    • Heathcote, J.E.1    Gane, E.J.2    de Man, A.3
  • 12
    • 33644818518 scopus 로고    scopus 로고
    • A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B
    • Chang TT, Gish RG, de Man R, et al. A comparison of entecavir and lamivudine for HBeAg-positive chronic hepatitis B. N Engl J Med. 2006;354(10):1001-1010.
    • (2006) N Engl J Med , vol.354 , Issue.10 , pp. 1001-1010
    • Chang, T.T.1    Gish, R.G.2    de Man, R.3
  • 13
    • 57349148151 scopus 로고    scopus 로고
    • Chronic hepatitis B: New goals, new treatment
    • Lai CL, Yuen MF. Chronic hepatitis B: new goals, new treatment. N Engl J Med. 2008;359(23):2488-2491.
    • (2008) N Engl J Med , vol.359 , Issue.23 , pp. 2488-2491
    • Lai, C.L.1    Yuen, M.F.2
  • 14
    • 0037468421 scopus 로고    scopus 로고
    • Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, et al. Adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. N Engl J Med. 2003;348(9):808-816.
    • (2003) N Engl J Med , vol.348 , Issue.9 , pp. 808-816
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 15
    • 37349120537 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in patients with chronic hepatitis B
    • Lai CL, Gane E, Liaw YF, et al. Telbivudine versus lamivudine in patients with chronic hepatitis B. N Engl J Med. 2007;357(25):2576-2588.
    • (2007) N Engl J Med , vol.357 , Issue.25 , pp. 2576-2588
    • Lai, C.L.1    Gane, E.2    Liaw, Y.F.3
  • 16
    • 33846067615 scopus 로고    scopus 로고
    • Two-year results from the globe trial in patients with hepatitis B: Greater clinical and antiviral efficacy for telbivudine (LDT) vs lamivudine [Abstract]
    • Lai CL, Gane E, Hsu CW, et al. Two-year results from the globe trial in patients with hepatitis B: greater clinical and antiviral efficacy for telbivudine (LDT) vs lamivudine [Abstract]. Hepatology. 2006;44 Suppl 1:222A.
    • (2006) Hepatology , vol.44 , Issue.SUPPL. 1
    • Lai, C.L.1    Gane, E.2    Hsu, C.W.3
  • 17
    • 61749092750 scopus 로고    scopus 로고
    • Two year tenofovir disoproxil fumarate (TDF) treatment and adenofovir dipivoxil (ADV) switch data in HbeAg-negative patients with chronic hepatitis B (Study 102), preliminary analysis [Abstract]
    • Marcellin P, Buti M, Krastev Z, et al. Two year tenofovir disoproxil fumarate (TDF) treatment and adenofovir dipivoxil (ADV) switch data in HbeAg-negative patients with chronic hepatitis B (Study 102), preliminary analysis [Abstract]. Hepatology. 2008;48 Suppl 4:370A.
    • (2008) Hepatology , vol.48 , Issue.SUPPL. 4
    • Marcellin, P.1    Buti, M.2    Krastev, Z.3
  • 18
    • 77956627491 scopus 로고    scopus 로고
    • Three years of tenofovir disoproxil (TDF) treatment in HbeAg-positive patients (HBeAg+) with chronic hepatitis B (Study 103), preliminary analysis [Abstract]
    • Marcellin P, Buti M, Krastev Z, et al. Three years of tenofovir disoproxil (TDF) treatment in HbeAg-positive patients (HBeAg+) with chronic hepatitis B (Study 103), preliminary analysis [Abstract]. Hepatology. 2009;50 Suppl 4:532A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL. 4
    • Marcellin, P.1    Buti, M.2    Krastev, Z.3
  • 19
    • 4644295202 scopus 로고    scopus 로고
    • Italian Association for the Study of the Liver (AISF) Lamivudine Study Group, Italy. Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine
    • Di Marco V, Marzano A, Lampertico P, et al. Italian Association for the Study of the Liver (AISF) Lamivudine Study Group, Italy. Clinical outcome of HBeAg-negative chronic hepatitis B in relation to virological response to lamivudine. Hepatology. 2004;40(4):883-891.
    • (2004) Hepatology , vol.40 , Issue.4 , pp. 883-891
    • di Marco, V.1    Marzano, A.2    Lampertico, P.3
  • 20
    • 33845671388 scopus 로고    scopus 로고
    • Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years
    • Adefovir Dipivoxil 438 Study Group
    • Hadziyannis SJ, Tassopoulos NC, Heathcote EJ, et al. Adefovir Dipivoxil 438 Study Group. Long-term therapy with adefovir dipivoxil for HBeAg-negative chronic hepatitis B for up to 5 years. Gastroenterology. 2006;131(6):1743-1751.
    • (2006) Gastroenterology , vol.131 , Issue.6 , pp. 1743-1751
    • Hadziyannis, S.J.1    Tassopoulos, N.C.2    Heathcote, E.J.3
  • 21
    • 67149117340 scopus 로고    scopus 로고
    • ETV re-treatment of nucleosidenaive HBeAg(-) [Abstract]
    • Senturk H, Lurie Y, Gadano A, et al. ETV re-treatment of nucleosidenaive HBeAg(-) [Abstract]. J Hepatol. 2007;46 Suppl 1: S197.
    • (2007) J Hepatol , vol.46 , Issue.SUPPL. 1
    • Senturk, H.1    Lurie, Y.2    Gadano, A.3
  • 22
    • 67149145458 scopus 로고    scopus 로고
    • Three years of entecavir (ETV) re-treatment of HBeAg(-) ETV patients who previously discontinued ETV treatment: Results from study ETV-901
    • Shouval D, Lai CL, Chang TT, et al. Three years of entecavir (ETV) re-treatment of HBeAg(-) ETV patients who previously discontinued ETV treatment: results from study ETV-901. Hepatology. 2008;48 Suppl 4:722A.
    • (2008) Hepatology , vol.48 , Issue.SUPPL. 4
    • Shouval, D.1    Lai, C.L.2    Chang, T.T.3
  • 23
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
    • BEHoLD AI463027 Study Group
    • Lai CL, Shouval D, Lok AS, et al; BEHoLD AI463027 Study Group. Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B. N Engl J Med. 2006;354(10):1011-1020.
    • (2006) N Engl J Med , vol.354 , Issue.10 , pp. 1011-1020
    • Lai, C.L.1    Shouval, D.2    Lok, A.S.3
  • 24
    • 33644822860 scopus 로고    scopus 로고
    • Entecavir versus lamivudine for patients with HBeAg-negative chronic hepatitis B
    • BEHoLD AI463027 Study Group, Erratum in
    • Erratum in: N Engl J Med. 2006;354(17):1863.
    • (2006) N Engl J Med , vol.354 , Issue.17 , pp. 1863
    • Lai, C.L.1    Shouval, D.2    Lok, A.S.3
  • 25
    • 33746720138 scopus 로고    scopus 로고
    • Continued virologic and biochemical improvement through 96 weeks of entecavir treatment in HBeAg(-) chronic hepatitis B patients (study ETV-027)
    • Shouval D, Akarca US, Hatzis G, et al. Continued virologic and biochemical improvement through 96 weeks of entecavir treatment in HBeAg(-) chronic hepatitis B patients (study ETV-027). J Hepatol. 2006;44 Suppl 2:S21-S22.
    • (2006) J Hepatol , vol.44 , Issue.SUPPL. 2
    • Shouval, D.1    Akarca, U.S.2    Hatzis, G.3
  • 26
    • 77955964465 scopus 로고    scopus 로고
    • Efficacy and safety outcomes after 4 years of telbivudine treatment in patients with chronic hepatitis B (CHB)
    • Wang Y, Thongsawat S, Gane EJ, et al. Efficacy and safety outcomes after 4 years of telbivudine treatment in patients with chronic hepatitis B (CHB). Hepatology. 2009;50 Suppl 4:533A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL. 4
    • Wang, Y.1    Thongsawat, S.2    Gane, E.J.3
  • 27
    • 79952967350 scopus 로고    scopus 로고
    • HBeAg+ and HBeAghepatitis B patients treated with tenofovir df showed no relationship between virologic breakthrough and emergence of genotypic changes in HBV polymerase
    • Snow-Lampart A, Chappell BJ, Curtis M, et al. HBeAg+ and HBeAghepatitis B patients treated with tenofovir df showed no relationship between virologic breakthrough and emergence of genotypic changes in HBV polymerase. Hepatology. 2009;50 Suppl 4:523A.
    • (2009) Hepatology , vol.50 , Issue.SUPPL. 4
    • Snow-Lampart, A.1    Chappell, B.J.2    Curtis, M.3
  • 28
    • 10744225554 scopus 로고    scopus 로고
    • Long-term safety of lamivudine treatment in patients with chronic hepatitis B
    • Lok AS, Lai CL, Leung N, et al. Long-term safety of lamivudine treatment in patients with chronic hepatitis B. Gastroenterology. 2003; 125(6):1714-1722.
    • (2003) Gastroenterology , vol.125 , Issue.6 , pp. 1714-1722
    • Lok, A.S.1    Lai, C.L.2    Leung, N.3
  • 29
    • 51349107091 scopus 로고    scopus 로고
    • Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B
    • Marcellin P, Chang TT, Lim SG, et al. Long-term efficacy and safety of adefovir dipivoxil for the treatment of hepatitis B e antigen-positive chronic hepatitis B. Hepatology. 2008;48(3):750-758.
    • (2008) Hepatology , vol.48 , Issue.3 , pp. 750-758
    • Marcellin, P.1    Chang, T.T.2    Lim, S.G.3
  • 30
    • 66149115173 scopus 로고    scopus 로고
    • Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naïve patients is rare through 5 years of therapy
    • Tenney DJ, Rose RE, Baldick CJ, et al. Long-term monitoring shows hepatitis B virus resistance to entecavir in nucleoside-naïve patients is rare through 5 years of therapy. Hepatology. 2009;49(5):1503-1514.
    • (2009) Hepatology , vol.49 , Issue.5 , pp. 1503-1514
    • Tenney, D.J.1    Rose, R.E.2    Baldick, C.J.3
  • 31
    • 58649096155 scopus 로고    scopus 로고
    • 2-year GLOBE trial results: Telbivudine is superior to lamivudine in patients with chronic hepatitis B
    • GLOBE Study Group
    • Liaw YF, Gane E, Leung N, et al. GLOBE Study Group. 2-year GLOBE trial results: telbivudine is superior to lamivudine in patients with chronic hepatitis B. Gastroenterology. 2009;136(2):486-495.
    • (2009) Gastroenterology , vol.136 , Issue.2 , pp. 486-495
    • Liaw, Y.F.1    Gane, E.2    Leung, N.3
  • 32
    • 58649108768 scopus 로고    scopus 로고
    • Hepatitis B: A "GLOBAL" health challenge
    • Fontana RJ. Hepatitis B: a "GLOBAL" health challenge. Gastroenterology. 2009;136(2):389-392.
    • (2009) Gastroenterology , vol.136 , Issue.2 , pp. 389-392
    • Fontana, R.J.1
  • 33
    • 48549107919 scopus 로고    scopus 로고
    • Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b
    • Buster EH, Flink HJ, Cakaloglu Y, et al. Sustained HBeAg and HBsAg loss after long-term follow-up of HBeAg-positive patients treated with peginterferon alpha-2b. Gastroenterology. 2008;135(2):459-467.
    • (2008) Gastroenterology , vol.135 , Issue.2 , pp. 459-467
    • Buster, E.H.1    Flink, H.J.2    Cakaloglu, Y.3
  • 34
    • 19944428132 scopus 로고    scopus 로고
    • HBV 99-01 Study Group; Rotterdam Foundation for Liver Research. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: A randomised trial
    • Janssen HL, van Zonneveld M, Senturk H, et al. HBV 99-01 Study Group; Rotterdam Foundation for Liver Research. Pegylated interferon alfa-2b alone or in combination with lamivudine for HBeAg-positive chronic hepatitis B: a randomised trial. Lancet. 2005;365(9454):123-129.
    • (2005) Lancet , vol.365 , Issue.9454 , pp. 123-129
    • Janssen, H.L.1    van Zonneveld, M.2    Senturk, H.3
  • 35
    • 4544239807 scopus 로고    scopus 로고
    • Peginterferon Alfa-2a HBeAg- Negative Chronic Hepatitis B Study Group. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B
    • Marcellin P, Lau GK, Bonino F, et al. Peginterferon Alfa-2a HBeAg- Negative Chronic Hepatitis B Study Group. Peginterferon alfa-2a alone, lamivudine alone, and the two in combination in patients with HBeAg-negative chronic hepatitis B. N Engl J Med. 2004;351(12): 1206-1217.
    • (2004) N Engl J Med , vol.351 , Issue.12 , pp. 1206-1217
    • Marcellin, P.1    Lau, G.K.2    Bonino, F.3
  • 36
    • 66449121130 scopus 로고    scopus 로고
    • Peginterferon alfa-2a in HBeAgnegative Chronic Hepatitis B Study Group. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a
    • Marcellin P, Bonino F, Lau GK, et al. Peginterferon alfa-2a in HBeAgnegative Chronic Hepatitis B Study Group. Sustained response of hepatitis B e antigen-negative patients 3 years after treatment with peginterferon alpha-2a. Gastroenterology. 2009;136(7):2169-2179:e1-e4.
    • (2009) Gastroenterology , vol.136 , Issue.7 , pp. 2169-2179
    • Marcellin, P.1    Bonino, F.2    Lau, G.K.3
  • 37
    • 77950615937 scopus 로고    scopus 로고
    • Current treatments for patients with HBeAg-positive chronic hepatitis B virus infection: A comparison focusing on HBeAg seroconversion
    • Lau GK. Current treatments for patients with HBeAg-positive chronic hepatitis B virus infection: a comparison focusing on HBeAg seroconversion. Liver Int. 2010;30(4):512-520.
    • (2010) Liver Int , vol.30 , Issue.4 , pp. 512-520
    • Lau, G.K.1
  • 38
    • 15944414076 scopus 로고    scopus 로고
    • Long term efficacy and safety of adefovir dipivoxil (ADV) 10 mg in HBeAg+ chronic hepatitis B (CHB) patients increasing serologic, virologic and biochemical response over time
    • Marcellin P, Chang TT, Lim S, et al. Long term efficacy and safety of adefovir dipivoxil (ADV) 10 mg in HBeAg+ chronic hepatitis B (CHB) patients increasing serologic, virologic and biochemical response over time. Hepatology. 2004;40(1) Suppl 4:655A.
    • (2004) Hepatology , vol.40 , Issue.SUPPL. 4
    • Marcellin, P.1    Chang, T.T.2    Lim, S.3
  • 39
    • 57149117201 scopus 로고    scopus 로고
    • Entecavir (ETV) results in higher HBV DNA reduction versus adefovir (ADV) in antiviralnaive HBeAg+ adults with high HBVDNA: Week 96 results (E.A.R.L.Y. study)
    • Leung N, Peng CY, Sollano J, et al. Entecavir (ETV) results in higher HBV DNA reduction versus adefovir (ADV) in antiviralnaive HBeAg+ adults with high HBVDNA: Week 96 results (E.A.R.L.Y. study). J Hepatol. 2008;48:S373-S374.
    • (2008) J Hepatol , vol.48
    • Leung, N.1    Peng, C.Y.2    Sollano, J.3
  • 40
    • 57149101516 scopus 로고    scopus 로고
    • Virologic, serologic, and biochemical outcomes through 2 years of treatment with entecavir and lamivudine in nucleoside-naive Chinese patients with chronic hepatitis B: A randomized, multicenter study
    • Yao G, Chen CW, Lu WL, et al. Virologic, serologic, and biochemical outcomes through 2 years of treatment with entecavir and lamivudine in nucleoside-naive Chinese patients with chronic hepatitis B: a randomized, multicenter study. Hepatol Int. 2008;2:486-493.
    • (2008) Hepatol Int , vol.2 , pp. 486-493
    • Yao, G.1    Chen, C.W.2    Lu, W.L.3
  • 41
    • 40949142486 scopus 로고    scopus 로고
    • Four-year entecavir treatment in nucleosidenaïve HBeAg(+) patients: Results from studies ETV-022 And -901
    • Han S, Chang T-T, Chao YC, et al. Four-year entecavir treatment in nucleosidenaïve HBeAg(+) patients: results from studies ETV-022 And -901. Hepatology. 2007;46(4) Suppl 1:654A.
    • (2007) Hepatology , vol.46 , Issue.SUPPL. 1
    • Han, S.1    Chang, T.-T.2    Chao, Y.C.3
  • 42
    • 39549113880 scopus 로고    scopus 로고
    • Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double-blind trial
    • Hou J, Yin YK, Xu D, et al. Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: results at 1 year of a randomized, double-blind trial. Hepatology. 2008;47:447-454.
    • (2008) Hepatology , vol.47 , pp. 447-454
    • Hou, J.1    Yin, Y.K.2    Xu, D.3
  • 43
    • 51049088452 scopus 로고    scopus 로고
    • Sustained response to peginterferon alfa-2a (40 kD) with or without lamivudine in Asian patients with HBeAg-positive and HBeAg-negative chronic hepatitis B
    • Piratvisuth T, Lau G, Chao YC, et al. Sustained response to peginterferon alfa-2a (40 kD) with or without lamivudine in Asian patients with HBeAg-positive and HBeAg-negative chronic hepatitis B. Hepatol Int. 2008;2(1):102-110.
    • (2008) Hepatol Int , vol.2 , Issue.1 , pp. 102-110
    • Piratvisuth, T.1    Lau, G.2    Chao, Y.C.3
  • 45
    • 34447340970 scopus 로고    scopus 로고
    • Cost-effectiveness of suppressing hepatitis B virus DNA in immune tolerant patients to prevent hepatocellular carcinoma and cirrhosis
    • Enriquez AD, Campbell MS, Reddy KR. Cost-effectiveness of suppressing hepatitis B virus DNA in immune tolerant patients to prevent hepatocellular carcinoma and cirrhosis. Aliment Pharmacol Ther. 2007;26(3):383-391.
    • (2007) Aliment Pharmacol Ther , vol.26 , Issue.3 , pp. 383-391
    • Enriquez, A.D.1    Campbell, M.S.2    Reddy, K.R.3
  • 46
    • 2942695736 scopus 로고    scopus 로고
    • Rapporto costo efficacia della terapia peginterferone alfa-2a+ribavirina in confronto a interferone alfa-2b+ribavirina in pazienti affetti da epatite cronica di tipo C precedentemente non trattati
    • Sullivan SD, Craxi A, Alberti A, et al. Rapporto costo efficacia della terapia peginterferone alfa-2a+ribavirina in confronto a interferone alfa-2b+ribavirina in pazienti affetti da epatite cronica di tipo C precedentemente non trattati. PharmacoEconomics. 2004;6:105-114.
    • (2004) PharmacoEconomics , vol.6 , pp. 105-114
    • Sullivan, S.D.1    Craxi, A.2    Alberti, A.3
  • 47
    • 18644369134 scopus 로고    scopus 로고
    • Treatment alternatives for chronic hepatitis B virus infection: A cost-effectiveness analysis
    • Kanwal F, Gralnek IM, Martin P, et al. Treatment alternatives for chronic hepatitis B virus infection: a cost-effectiveness analysis. Ann Intern Med. 2005;142(10):821-831.
    • (2005) Ann Intern Med , vol.142 , Issue.10 , pp. 821-831
    • Kanwal, F.1    Gralnek, I.M.2    Martin, P.3
  • 48
    • 0033651417 scopus 로고    scopus 로고
    • A comprehensive league table of cost-utility ratios and a sub-table of "panel-worthy" studies
    • Chapman RH, Stone PW, Sandberg EA, et al. A comprehensive league table of cost-utility ratios and a sub-table of "panel-worthy" studies. Med Decis Making. 2000;20(4):451-467.
    • (2000) Med Decis Making , vol.20 , Issue.4 , pp. 451-467
    • Chapman, R.H.1    Stone, P.W.2    Sandberg, E.A.3
  • 49
    • 79952922800 scopus 로고    scopus 로고
    • Health Ministry, Nomenclatore Delle Prestazioni Di Assistenza Specialistica Ambulatoriale, Ministero della Salute
    • Health Ministry. National Tariff Nomenclature. Nomenclatore delle Prestazioni di assistenza specialistica ambulatoriale. Ministero della Salute; 2010.
    • (2010) National Tariff Nomenclature
  • 51
    • 79952912978 scopus 로고    scopus 로고
    • Il costo del trapianto d'organo: Risultati di uno studio condotto presso l'Azienda Ospedaliera di Padova
    • valori attualizzati al
    • Tumiatti C, Bezzon C, Guasti F, Franchin M. Il costo del trapianto d'organo: risultati di uno studio condotto presso l'Azienda Ospedaliera di Padova. Azienda Ospedaliera di Padova. 1999:39. valori attualizzati al 2009.
    • (1999) Azienda Ospedaliera Di Padova , vol.39
    • Tumiatti, C.1    Bezzon, C.2    Guasti, F.3    Franchin, M.4
  • 54
    • 33748063371 scopus 로고    scopus 로고
    • The National Institute for Health and Clinical Excellence, Second ed, Accessed July 14, 2010
    • The National Institute for Health and Clinical Excellence. Social value judgements: principles for the development of NICE guidance. Second ed. 2008. http://www.nice.org.uk/media/C18/30/SVJ2PUBLICATION2008.pdf. Accessed July 14, 2010.
    • (2008) Social Value Judgements: Principles for the Development of NICE Guidance
  • 55
    • 69949132951 scopus 로고    scopus 로고
    • Modeling the cost-effectiveness of different oral antiviral therapies in patients with chronic hepatitis B
    • Buti M, Brosa M, Casado MA, et al. Modeling the cost-effectiveness of different oral antiviral therapies in patients with chronic hepatitis B. J Hepatol. 2009;51(4):640-646.
    • (2009) J Hepatol , vol.51 , Issue.4 , pp. 640-646
    • Buti, M.1    Brosa, M.2    Casado, M.A.3
  • 56
    • 78650083042 scopus 로고    scopus 로고
    • Cost-utility analysis of tenofovir disoproxil fumarate in the treatment of chronic hepatitis B
    • September 3, [Epub ahead of print]
    • Dakin H, Bentley A, Dusheiko G. Cost-utility analysis of tenofovir disoproxil fumarate in the treatment of chronic hepatitis B. Value Health. September 3, 2010. [Epub ahead of print].
    • (2010) Value Health
    • Dakin, H.1    Bentley, A.2    Dusheiko, G.3
  • 57
    • 77952810290 scopus 로고    scopus 로고
    • Proposta di linee guida per la valutazione economica degli interventi sanitari
    • Associazione Italiana di Economia Sanitaria (AIES)
    • Associazione Italiana di Economia Sanitaria (AIES). Proposta di linee guida per la valutazione economica degli interventi sanitari. PharmacoEconomics - Italian Research Articles. 2009;11: 83-93.
    • (2009) PharmacoEconomics-Italian Research Articles , vol.11 , pp. 83-93
  • 59
    • 0141729339 scopus 로고    scopus 로고
    • Controvalore economico del farmaco e beneficio clinico: Stato dell'arte della metodologia e applicazione di un algoritmo farmacoeconomico
    • Messori A, Santarlasci B, Trippoli S, Vaiani M. Controvalore economico del farmaco e beneficio clinico: Stato dell'arte della metodologia e applicazione di un algoritmo farmacoeconomico. PharmacoEconomics - Italian Research Articles. 2003;5:53-67.
    • (2003) PharmacoEconomics-Italian Research Articles , vol.5 , pp. 53-67
    • Messori, A.1    Santarlasci, B.2    Trippoli, S.3    Vaiani, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.