Epidemiological evidence for possible radiation hormesis from radon exposure: A case-control study conducted in Worcester, MA

Dose-Response

Volumn 9, Issue 1, 2011, Pages 59-75

  Thompson, Richard E ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Adaptive response; Hormesis; Lung cancer; Radon

Indexed keywords

RADON;

ARTICLE; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; DEMOGRAPHY; DOSIMETRY; HORMESIS; HUMAN; LUNG CANCER; OCCUPATIONAL EXPOSURE; RADIATION EXPOSURE; SMOKING; STATISTICAL ANALYSIS; UNITED STATES;

EID: 79952968434     PISSN: None     EISSN: 15593258     Source Type: Journal    
DOI: 10.2203/dose-response.10-026.Thompson     Document Type: Article

References (13)

1. Darby S, Hill D, Doll R. 2001. Radon: A likely carcinogen at all exposures. Ann Oncol 12: 1341-1351.
2. Darby S, Hill D, Auvinen A, Barros-Dios JM, Baysson H, Bochicchio F, Deo H, Falk R, Forastiere F, Hakama M, Heid I, Kreienbrock L, Kreuzer M, Lagarde F, Makelainen I, Muirhead C, Oberaigner W, Pershagen G, Ruano-Ravina A, Ruosteenoja E, Schaffrath Rosario A, Tirmarche M, Tomasek L, Whitley E, Wichmann H-E, Doll R. 2005. Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies. BMJ 330:223-228.
3. Day T, Zeng G, Hooker A, Bhat M, Scott BR, Turner DR, Sykes PJ. 2007. Adaptive response for chromosomal inversions in pKZ1 mouse prostate induced by low doses of X radiation delivered after a high dose. Radiat Res 167:682-692.
4. Field RW, Steck DJ, Smith BJ, Brus CP, Fisher EL, Neuberger JS, Platz CE, Robinson RA, Woolson RF,Lynch CF. 2000. Residential radon gas exposure and lung cancer: the Iowa radon lung cancer study. Am J Epidemiol 151:1091-1102.
5. Krewski D, Lubin JH, Zielinski JM, Alavanja M, Catalan VS, Field RW, Klotz JB, Letourneau EG, Lynch CF, Lyon JI, Sandler DP, Schoenberg JB, Steck DJ, Stolwijk JA, Weinberg C, Wilcox HB. 2006. Residential radon and risk of lung cancer: a combined analysis of North American case-control Studies. J Toxicol Environ Health 69:533-597.
6. Lubin JH, Boice JD Jr, Edling C, Hornung RW, Howe GR, Kunz E, Kusiak RA, Morrison HI, Radford EP, Samet JM. 1995. Lung cancer in radon-exposed miners and estimation of risk from indoor exposure. J Natl Cancer Inst. 87: 817-827.
7. NRC (National Research Council). 1999. Health effects of exposure to Radon, BEIR VI. Committee on Health Risks of Exposure to Radon. Board on Radiation Effects Research, Commission on Life Sciences. Washington, DC: National Academy Press, 1999.
8. Redpath J, Liang D, Taylor T, James C, Christie E, Elmore E. 2001. The shape of the dose-response curve for radiation-induced neoplastic transformation in vitro: evidence for an adaptive response against neoplastic transformation at low doses of low-LET radiation. Radiat Res 156: 700-707.
9. Samet JM, Pathak DR, Morgan MV, Key CR, Valdivia AA, Lubin JH. 1991. Lung cancer mortality and exposure to radon progeny in a cohort of New Mexico underground uranium miners. Health Phys 61: 745-752.
10. Samet JM. 2006. Residential radon and lung cancer: end of the story? Toxicol Environ Health 69: 527-531.
11. Scott BR, Belinsky SA, Leng S, Lin Y, Wilder JA, Damiani LA. 2009. Radiation-stimulated epigenetic reprogramming of adaptive-response genes in the lung: an evolutionary gift for mounting adaptive protection against lung cancer. Dose-Response 7: 104-131.
12. StataCorp. Stata Statistical Software: Release 10.0. College Station, TX: Stata Corp. 2009
13. Thompson RE, Nelson DF, Popkin JH, Popkin Z. 2008. Case-control study of lung cancer risk from residential radon exposure in Worcester County, Massachusetts. Health Physics 94: 228-241.