Amphotericin-B-loaded polymersomes formulation (PAMBO) based on (PEG)3-PLA copolymers: An in vivo evaluation in a murine model

Molecular Pharmaceutics

Volumn 8, Issue 1, 2011, Pages 204-212

  Jain, Jay Prakash ^a   Jatana, Manu ^b,c   Chakrabarti, Arunaloke ^c   Kumar, Neeraj ^a  

^a NATIONAL INSTITUTE OF PHARMACEUTICAL EDUCATION AND RESEARCH NIPER   (India)

^b SHOOLINI UNIVERSITY   (India)

^c POSTGRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

Amphotericin B; Candidiasis; Nanomedicine; Polymersomes; Toxicity

Indexed keywords

AMPHOTERICIN B DEOXYCHOLATE; AMPHOTERICIN B DERIVATIVE; AMPHOTERICIN B LIPID COMPLEX; AMPHOTERICIN B LOADED POLYMERSOME; CREATININE; MACROGOL; NITROGEN; POLYLACTIC ACID; UNCLASSIFIED DRUG; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CANDIDA ALBICANS; COLONY FORMING UNIT; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; DRUG EFFICACY; DRUG FATALITY; DRUG FORMULATION; DRUG HALF LIFE; DRUG SAFETY; DRUG TISSUE LEVEL; FEMALE; HISTOPATHOLOGY; IMMUNE DEFICIENCY; IN VIVO STUDY; INVASIVE CANDIDIASIS; KIDNEY; LEISHMANIASIS; LIFE EXPECTANCY; LIVER; LUNG; MALE; MAXIMUM PLASMA CONCENTRATION; MOUSE; MYCOSIS; NEPHROTOXICITY; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; SPLEEN; SURVIVAL RATE; TARGET ORGAN; TIME TO MAXIMUM PLASMA CONCENTRATION; TISSUE DISTRIBUTION; UREA NITROGEN BLOOD LEVEL;

AMPHOTERICIN B; ANIMALS; ANTIFUNGAL AGENTS; CANDIDA ALBICANS; KIDNEY; MALE; MICE; MICE, INBRED BALB C; POLYETHYLENE GLYCOLS; POLYMERS; RATS; RATS, SPRAGUE-DAWLEY; SPLEEN;

EID: 79952953185     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp100267k     Document Type: Article

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