Strategies for the rapid construction of conditionally-replicating HSV-1 vectors expressing foreign genes as anticancer therapeutic agents

Molecular Pharmaceutics

Volumn 8, Issue 1, 2011, Pages 44-49

  Parker, Jacqueline N ^a,b,d   Zheng, Xiaojia ^b   Luckett Jr , William ^a   Markert, James M ^b,c   Cassady, Kevin A ^a,b  

^a University of Alabama at Birmingham   (United States)

^b UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^c University of Alabama at Birmingham   (United States)

^d NONE   (United States)

Author keywords

134.5; Bridge plasmid; Co infection; Conditionally replicating; HSV 1; Marker rescue; UL39; Virus construction

Indexed keywords

ANTINEOPLASTIC AGENT; BETA GALACTOSIDASE; BIOLOGICAL FACTOR; CONDITIONALLY REPLICATING HERPESVIRUS 1 VECTOR; CRE RECOMBINASE; CYTOSINE DEAMINASE; G 207; HERPESVIRUS VECTOR; M 1000; MYELOID DIFFERENTIATION FACTOR 116; PLASMID DNA; RED FLUORESCENT PROTEIN; RESTRICTION ENDONUCLEASE; SITIMAGENE CERADENOVEC; SPACER DNA; UNCLASSIFIED DRUG; VIRUS DNA;

BACTERIAL ARTIFICIAL CHROMOSOME; BRIDGE PLASMID METHOD; CANCER GENE THERAPY; COSMID; GENE CASSETTE; GENE DELETION; GENE DOSAGE; GENE EXPRESSION; GENE INSERTION; GENE LOCUS; GENE TARGETING; GENETIC ENGINEERING; GENETIC PROCEDURES; GENETIC TRANSFECTION; GLIOBLASTOMA; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CYTOMEGALOVIRUS; INVERTED REPEAT; LOXP SITE; MARKER RESCUE METHOD; MIXED INFECTION; MUTAGENESIS; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; RESTRICTION SITE; REVIEW; SKIN FIBROBLAST; SOUTHERN BLOTTING; TARGETING PLASMID METHOD; VIRAL GENE DELIVERY SYSTEM; VIRUS GENOME; VIRUS REPLICATION; VIRUS STRAIN; WILD TYPE;

GENE THERAPY; GENETIC VECTORS; HERPESVIRUS 1, HUMAN; HUMANS; NEOPLASMS; VIRUS REPLICATION;

EID: 79952908291     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp100230y     Document Type: Review

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