Structure and mechanism of the chalcogen-detoxifying protein TehB from Escherichia coli

Biochemical Journal

Volumn 435, Issue 1, 2011, Pages 85-91

  Choudhury, Hassanul G ^a   Cameron, Alexander D ^a   Iwata, So ^a   Beis, Konstantinos ^a  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Chalcogen; Detoxification; Methyltransferase; Nucleophilic attack; Selenium oxyanion; Tellurite oxyanion

Indexed keywords

ARGININE; BACTERIAL PROTEIN; HISTIDINE; METHYLTRANSFERASE; S ADENOSYLHOMOCYSTEINE; SELENIUM; SINEFUNGIN; TEHB PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ESCHERICHIA COLI; MOLECULAR MECHANICS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN STRUCTURE;

ADENOSINE; BIOCATALYSIS; CATALYTIC DOMAIN; CHALCOGENS; CONSENSUS SEQUENCE; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI K12; ESCHERICHIA COLI PROTEINS; KINETICS; METHYLATION; MUTAGENESIS, SITE-DIRECTED; MUTANT PROTEINS; ORGANOSELENIUM COMPOUNDS; PROTEIN CONFORMATION; RECOMBINANT PROTEINS; S-ADENOSYLHOMOCYSTEINE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; TELLURIUM;

ESCHERICHIA COLI;

EID: 79952839422     PISSN: 02646021     EISSN: 14708728     Source Type: Journal    
DOI: 10.1042/BJ20102014     Document Type: Article

References (19)

1. Ganther, H. E. (1999) Selenium metabolism, selenoproteins and mechanisms of cancer prevention: complexities with thioredoxin reductase. Carcinogenesis 20, 1657-1666
2. Sabaty, M., Avazeri, C., Pignol, D. and Vermeglio, A. (2001) Characterization of the reduction of selenate and tellurite by nitrate reductases. Appl. Environ. Microbiol. 67, 5122-5126
3. Avazeri, C., Turner, R. J., Pommier, J., Weiner, J. H., Giordano, G. and Vermeglio, A. (1997) Tellurite reductase activity of nitrate reductase is responsible for the basal resistance of Escherichia coli to tellurite. Microbiology 143, 1181-1189
4. Borsetti, F., Borghese, R., Francia, F., Randi, M. R., Fedi, S. and Zannoni, D. (2003) Reduction of potassium tellurite to elemental tellurium and its effect on the plasma membrane redox components of the facultative phototroph Rhodobacter capsulatus. Protoplasma 221, 153-161
5. Ollivier, P. R., Bahrou, A. S., Marcus, S., Cox, T., Church, T. M. and Hanson, T. E. (2008) Volatilization and precipitation of tellurium by aerobic, tellurite-resistant marine microbes. Appl. Environ. Microbiol. 74, 7163-7173
6. Ranjard, L., Nazaret, S. and Cournoyer, B. (2003) Freshwater bacteria can methylate selenium through the thiopurine methyltransferase pathway. Appl. Environ. Microbiol. 69, 3784-3790
7. Ranjard, L., Prigent-Combaret, C., Favre-Bonte, S., Monnez, C., Nazaret, S. and Cournoyer, B. (2004) Characterization of a novel selenium methyltransferase from freshwater bacteria showing strong similarities with the calicheamicin methyltransferase. Biochim. Biophys. Acta 1679, 80-85
8. Ranjard, L., Prigent-Combaret, C., Nazaret, S. and Cournoyer, B. (2002) Methylation of inorganic and organic selenium by the bacterial thiopurine methyltransferase. J. Bacteriol. 184, 3146-3149
9. Cournoyer, B., Watanabe, S. and Vivian, A. (1998) A tellurite-resistance genetic determinant from phytopathogenic pseudomonads encodes a thiopurine methyltransferase: evidence of a widely-conserved family of methyltransferases. Biochim. Biophys. Acta 1397, 161-168
10. Challenger, F. (1945) Biological methylation. Chem. Rev. 36, 315-361
11. Challenger, F. (1951) Biological methylation. Adv. Enzymol. Relat. Subj. Biochem. 12, 429-491
12. Liu, M., Turner, R. J., Winstone, T. L., Saetre, A., Dyllick-Brenzinger, M., Jickling, G., Tari, L. W., Weiner, J. H. and Taylor, D. E. (2000) Escherichia coliTehB requires S-adenosylmethionine as a cofactor to mediate tellurite resistance. J. Bacteriol. 182, 6509-6513
13. Choudhury, H. G. and Beis, K. (2010) Crystallization and initial X-ray diffraction analysis of the tellurite-resistance S-adenosyl-L-methionine transferase protein TehB from Escherichia coli. Acta Crystallogr. Sect. F Struct. Biol. Crystallogr. Commun. 66, 1496-1499
14. McCoy, A. J., Grosse-Kunstleve, R. W., Adams, P. D., Winn, M. D., Storoni, L. C. and Read, R. J. (2007) Phaser crystallographic software. J. Appl. Crystallogr. 40, 658-674
15. Murshudov, G. N., Vagin, A. A. and Dodson, E. J. (1997) Refinement of macromolecular structures by the maximum-likelihood method. Acta Crystallogr. Sect. D Biol. Crystallogr. 53, 240-255
16. Emsley, P. and Cowtan, K. (2004) Coot: model-building tools for molecular graphics. Acta Crystallogr. Sect. D Biol. Crystallogr. 60, 2126-2132
17. Langer, G., Cohen, S. X., Lamzin, V. S. and Perrakis, A. (2008) Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7. Nat. Protoc. 3, 1171-1179
18. Whitby, P. W., Seale, T. W., Morton, D. J., VanWagoner, T. M. and Stull, T. L. (2010) Characterization of the Haemophilus influenzae tehB gene and its role in virulence. Microbiology 156, 1188-1200
19. Dyllick-Brenzinger, M., Liu, M., Winstone, T. L., Taylor, D. E. and Turner, R. J. (2000) The role of cysteine residues in tellurite resistance mediated by the TehAB determinant. Biochem. Biophys. Res. Commun. 277, 394-400