Long-term efficacy and safety of cyclosporine as a rescue therapy in acute, steroid-refractory severe ulcerative colitis: Switching to infliximab is more effective than treating with concomitant immunomodulators

Journal of Clinical Gastroenterology

Volumn 45, Issue 4, 2011, Pages 380-381

  Molnár, Tamás ^a   Farkas, Klaudia ^a   Nyári, Tibor ^a   Szepes, Zoltán ^a   Nagy, Ferenc ^a   Wittmann, Tibor ^a  

^a UNIVERSITY OF SZEGED   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOSALICYLIC ACID; AZATHIOPRINE; CYCLOSPORIN; INFLIXIMAB; MERCAPTOPURINE; METHYLPREDNISOLONE;

COLON RESECTION; DISEASE SEVERITY; DRUG EFFICACY; DRUG SAFETY; DRUG SUBSTITUTION; DRUG WITHDRAWAL; HUMAN; LETTER; PRIORITY JOURNAL; TREATMENT OUTCOME; ULCERATIVE COLITIS; UNSPECIFIED SIDE EFFECT;

6-MERCAPTOPURINE; ACUTE DISEASE; ADOLESCENT; ADULT; AGED; ANTIBODIES, MONOCLONAL; COLECTOMY; COLITIS, ULCERATIVE; CYCLOSPORINE; DRUG THERAPY, COMBINATION; FEMALE; HOSPITALIZATION; HUMANS; IMMUNOSUPPRESSIVE AGENTS; LENGTH OF STAY; MALE; MIDDLE AGED; SALVAGE THERAPY; SEVERITY OF ILLNESS INDEX; TIME FACTORS; YOUNG ADULT;

EID: 79952819227     PISSN: 01920790     EISSN: None     Source Type: Journal    
DOI: 10.1097/MCG.0b013e318205e129     Document Type: Letter

References (3)

1. Cheifetz AS, Stern J, Garud S, et al. Cyclosporine is safe and effective in patients with severe ulcerative colitis. J Clin Gastroenterol. 2011;45:107-112.
2. Actis GC, Fadda M, David E, et al. Colectomy rate in steroid-refractory colitis initially responsive to cyclosporin: a long-term retrospective cohort study. BMC Gastroenterology. 2007;7:13.
3. Bamba S, Tsujikawa T, Inatomi O, et al. Factors affecting the efficacy of cyclosporin A therapy for refractory ulcerative colitis. J Gastroenterol Hepatol. 2010;25:494-498.