Psoriatic alopecia/alopecia areata-like reactions secondary to anti-tumor necrosis factor-α therapy: A novel cause of noncicatricial alopecia

American Journal of Dermatopathology

Volumn 33, Issue 2, 2011, Pages 161-166

  Doyle, Leona A ^a   Sperling, Leonard C ^b   Baksh, Shashi ^c   Lackey, Jeffrey ^b   Thomas, Brian ^b   Vleugels, Ruth Ann ^a   Qureshi, Abrar A ^a   Velazquez, Elsa F ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b Uniformed Services University of the Health Sciences   (United States)

^c Pennsylvania Speciality Pathology   (United States)

Author keywords

alopecia; Anti TNF; areata; psoriasis; psoriatic alopecia

Indexed keywords

ADALIMUMAB; CERTOLIZUMAB PEGOL; CLOBETASOL; CORTICOSTEROID; INFLIXIMAB; STEROID; TRIAMCINOLONE; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ACANTHOSIS; ADULT; ALOPECIA; ALOPECIA AREATA; ARTICLE; CASE REPORT; CROHN DISEASE; DRUG SUBSTITUTION; DRUG WITHDRAWAL; EOSINOPHIL; EPIDERMIS; FEMALE; HAIR FOLLICLE; HISTOPATHOLOGY; HUMAN; INFLAMMATION; NEUTROPHIL; PARAKERATOSIS; PLASMA CELL; PRIORITY JOURNAL; PSORIASIS; PSORIATIC ALOPECIA; PUSTULE; SCALP; SKIN BIOPSY;

ADULT; ALOPECIA; ANTI-INFLAMMATORY AGENTS; ANTIBODIES, MONOCLONAL; CROHN DISEASE; HUMANS; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 79952818972     PISSN: 01931091     EISSN: None     Source Type: Journal    
DOI: 10.1097/DAD.0b013e3181ef7403     Document Type: Article

References (13)

1. Lee HH, Song IH, Friedrich M, et al. Cutaneous side-effects in patients with rheumatic diseases during application of tumour necrosis factor-alpha antagonists. Br J Dermatol. 2007;156:486-491.
2. Collamer AN, Guerrero KT, Henning JS, et al. Psoriatic skin lesions induced by tumor necrosis factor antagonist therapy: a literature review and potential mechanisms of action. Arthritis Rheum. 2008;59:996-1001. (Pubitemid 351990997)
3. Nakagomi D, Harada K, Yagasaki A, et al. Psoriasiform eruption associated with alopecia areata during infliximab therapy. Clin Exp Dermatol. 2009;34:923-924.
4. El Shabrawi-Caelen L, La Placa M, Vincenzi C, et al. Adalimumab-induced psoriasis of the scalp with diffuse alopecia: a severe potentially irreversible cutaneous side effect of TNF-alpha blockers. Inflamm Bowel Dis. 2010;16:182-183.
5. Ettefagh L, Nedorost S, Mirmirani P. Alopecia areata in a patient using infliximab: new insights into the role of tumor necrosis factor on human hair follicles. Arch Dermatol. 2004;140:1012. (Pubitemid 39062659)
6. Kirshen C, Kanigsberg N. Alopecia areatafollowing adalimumab. J Cutan Med Surg. 2009;13:48-50.
7. Lowes MA, Bowcock AM, Krueger JG. Pathogenesis and therapy of psoriasis. Nature. 2007;445:866-873.
8. Weedon D. Skin Pathology. 2nd ed. London; UK: Churchill Livingstone; 2002.
9. Bardazzi F, Fanti PA, Orlandi C, et al. Psoriatic scarring alopecia: observations in four patients. Int J Dermatol. 1999;38:765-768. (Pubitemid 29515478)
10. Runne U, Kroneisen-Wiersma P. Psoriatic alopecia: acute and chronic hair loss in 47 patients with scalp psoriasis. Dermatology. 1992;185:82-87.
11. Shuster S. Psoriatic alopecia. Br J Dermatol. 1972;87:73-77.
12. Sperling LC. Alopeciaareata. In: An Atlas of Hair Pathology with Clinical Correlations. New York, NY: Parthenon Publishing; 2003 p. 63-78.
13. Tosti A, Pazzaglia M, Starace M, et al. Alopecia areata during treatment with biologic agents. Arch Dermatol. 2006;142:1653-1654. (Pubitemid 44969232)