-
1
-
-
33744999455
-
12 receptor
-
DOI 10.2174/138161206776361318
-
12 receptor. Curr Pharm Des. 2006;12:1255-1259. (Pubitemid 44082134)
-
(2006)
Current Pharmaceutical Design
, vol.12
, Issue.10
, pp. 1255-1259
-
-
Storey, R.F.1
-
2
-
-
75749102996
-
Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans
-
Farid NA, Kurihara A, Wrighton SA. Metabolism and disposition of the thienopyridine antiplatelet drugs ticlopidine, clopidogrel, and prasugrel in humans. J Clin Pharmacol. 2010;50:126-142.
-
(2010)
J Clin Pharmacol.
, vol.50
, pp. 126-142
-
-
Farid, N.A.1
Kurihara, A.2
Wrighton, S.A.3
-
3
-
-
18044378766
-
12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis
-
DOI 10.1055/s-2005-869523
-
12 adenosine diphosphate-receptor antagonists for the prevention of atherothrombosis. Semin Thromb Hemost. 2005;31:174-183. (Pubitemid 40605192)
-
(2005)
Seminars in Thrombosis and Hemostasis
, vol.31
, Issue.2
, pp. 174-183
-
-
Savi, P.1
Herbert, J.-M.2
-
4
-
-
70450199115
-
Focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update)
-
2009 ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
-
Kushner FG, Hand M, Smith SC Jr, et al. 2009 focused updates: ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction (updating the 2004 guideline and 2007 focused update) and ACC/AHA/SCAI guidelines on percutaneous coronary intervention (updating the 2005 guideline and 2007 focused update) a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. JAm Coll Cardiol. 2009;54:2205-2241.
-
(2009)
JAm Coll Cardiol.
, vol.54
, pp. 2205-2241
-
-
Kushner, F.G.1
Hand, M.2
Smith Jr., S.C.3
-
5
-
-
0034762075
-
Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement [1]
-
Muller I, Seyfarth M, Rüdiger S, et al. Effect of a high loading dose of clopidogrel on platelet function in patients undergoing coronary stent placement. Heart. 2001;85:92-93. (Pubitemid 32973418)
-
(2001)
Heart
, vol.85
, Issue.1
, pp. 92-93
-
-
Muller, I.1
Seyfarth, M.2
Rudiger, S.3
Wolf, B.4
Pogatsa-Murray, G.5
Schomig, A.6
Gawaz, M.7
-
6
-
-
18144371221
-
The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting
-
DOI 10.1016/j.jacc.2005.01.030
-
Gurbel PA, Bliden KP, Hayes KM, et al. The relation of dosing to clopidogrel responsiveness and the incidence of high post-treatment platelet aggregation in patients undergoing coronary stenting. JAm Coll Cardiol. 2005;45:1392-1396. (Pubitemid 40615608)
-
(2005)
Journal of the American College of Cardiology
, vol.45
, Issue.9
, pp. 1392-1396
-
-
Gurbel, P.A.1
Bliden, K.P.2
Hayes, K.M.3
Yoho, J.A.4
Herzog, W.R.5
Tantry, U.S.6
-
7
-
-
27744516843
-
Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: Results of the ISAR-CHOICE (intracoronary stenting and antithrombotic regimen: Choose between 3 high oral doses for immediate clopidogrel effect) trial
-
DOI 10.1161/CIRCULATIONAHA.105.559088
-
von Beckerath N, Taubert D, Pogatsa-Murray G, et al. Absorption, metabolization, and antiplatelet effects of 300-, 600-, and 900-mg loading doses of clopidogrel: results of the ISAR-CHOICE (Intracoronary Stenting and Antithrombotic Regimen: Choose Between 3 High Oral Doses for Immediate Clopidogrel Effect) Trial. Circulation. 2005;112: 2946-2950. (Pubitemid 41612296)
-
(2005)
Circulation
, vol.112
, Issue.19
, pp. 2946-2950
-
-
Von Beckerath, N.1
Taubert, D.2
Pogatsa-Murray, G.3
Schomig, E.4
Kastrati, A.5
Schomig, A.6
-
8
-
-
19644372173
-
Time dependence of platelet inhibition after a 600-mg loading dose of clopidogrel in a large, unselected cohort of candidates for percutaneous coronary intervention
-
DOI 10.1161/01.CIR.0000160869.75810.98
-
Hochholzer W, Trenk D, Frundi D, et al. Time dependence of platelet inhibition after a 600-mg loading dose ofclopidogrel in a large, unselected cohort of candidates for percutaneous coronary intervention. Circulation. 2005;111:2560-2564. (Pubitemid 40740853)
-
(2005)
Circulation
, vol.111
, Issue.20
, pp. 2560-2564
-
-
Hochholzer, W.1
Trenk, D.2
Frundi, D.3
Blanke, P.4
Fischer, B.5
Andris, K.6
Bestehorn, H.-P.7
Buttner, H.J.8
Neumann, F.-J.9
-
9
-
-
33747874088
-
A Randomized Comparison of High Clopidogrel Loading Doses in Patients With Non-ST-Segment Elevation Acute Coronary Syndromes. The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) Trial
-
DOI 10.1016/j.jacc.2006.04.090, PII S0735109706016421
-
Montalescot G, Sideris G, Meuleman C, et al; ALBION Trial Investigators. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: the ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. JAm Coll Cardiol. 2006. 48. 931-938. (Pubitemid 44292463)
-
(2006)
Journal of the American College of Cardiology
, vol.48
, Issue.5
, pp. 931-938
-
-
Montalescot, G.1
Sideris, G.2
Meuleman, C.3
Bal-dit-Sollier, C.4
Lellouche, N.5
Steg, Ph.G.6
Slama, M.7
Milleron, O.8
Collet, J.-P.9
Henry, P.10
Beygui, F.11
Drouet, L.12
-
10
-
-
57149119456
-
Randomized trial comparing 600-with 300-mg loading dose ofclopidogrel in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: Results of the Platelet Responsiveness to Aspirin and Clopidogrel and Troponin Increment after Coronary intervention in Acute coronary Lesions (PRACTICAL) Trial
-
Yong G, Rankin J, Ferguson L, et al. Randomized trial comparing 600-with 300-mg loading dose ofclopidogrel in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: results of the Platelet Responsiveness to Aspirin and Clopidogrel and Troponin Increment after Coronary intervention in Acute coronary Lesions (PRACTICAL) Trial. Am Heart J. 2009;157:60.e1-60.e9.
-
(2009)
Am Heart J.
, vol.157
-
-
Yong, G.1
Rankin, J.2
Ferguson, L.3
-
11
-
-
33646732608
-
Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease
-
Jernberg T, Payne CD, Winters KJ, et al. Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease. Eur Heart J. 2006;27:1166-1173.
-
(2006)
Eur Heart J.
, vol.27
, pp. 1166-1173
-
-
Jernberg, T.1
Payne, C.D.2
Winters, K.J.3
-
12
-
-
36348977461
-
Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel
-
DOI 10.1097/FJC.0b013e3181492209, PII 0000534420071100000013
-
Payne CD, Li YG, Small DS, et al. Increased active metabolite formation explains the greater platelet inhibition with prasugrel compared to high-dose clopidogrel. J Cardiovasc Pharmacol. 2007;50:555-562. (Pubitemid 350146459)
-
(2007)
Journal of Cardiovascular Pharmacology
, vol.50
, Issue.5
, pp. 555-562
-
-
Payne, C.D.1
Li, Y.G.2
Small, D.S.3
Ernest II, C.S.4
Farid, N.A.5
Jakubowski, J.A.6
Brandt, J.T.7
Salazar, D.E.8
Winters, K.J.9
-
13
-
-
36148983750
-
Prasugrel versus clopidogrel in patients with acute coronary syndromes
-
DOI 10.1056/NEJMoa0706482
-
Wiviott SD, Braunwald E, McCabe CH, et al; TRITON-TIMI 38 Investigators. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N Engl J Med. 2007;357:2001-2015. (Pubitemid 350106708)
-
(2007)
New England Journal of Medicine
, vol.357
, Issue.20
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
Montalescot, G.4
Ruzyllo, W.5
Gottlieb, S.6
Neumann, F.-J.7
Ardissino, D.8
De Servi, S.9
Murphy, S.A.10
Riesmeyer, J.11
Weerakkody, G.12
Gibson, C.M.13
Antman, E.M.14
-
14
-
-
38949144302
-
Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects
-
DOI 10.1080/09537100801891640, PII 793332448
-
Payne CD, Li YG, Brandt JT, et al. Switching directly to prasugrel from clopidogrel results in greater inhibition of platelet aggregation in aspirin-treated subjects. Platelets. 2008;19:275-281. (Pubitemid 351874155)
-
(2008)
Platelets
, vol.19
, Issue.4
, pp. 275-281
-
-
Payne, C.D.1
Li, Y.G.2
Brandt, J.T.3
Jakubowski, J.A.4
Small, D.S.5
Farid, N.A.6
Salazar, D.E.7
Winters, K.J.8
-
15
-
-
37849002889
-
12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease
-
12 receptor-mediated platelet inhibition than clopidogrel due to more efficient generation of its active metabolite in aspirin-treated patients with coronary artery disease. Eur Heart J. 2008;29:21-30.
-
(2008)
Eur Heart J.
, vol.29
, pp. 21-30
-
-
Wallentin, L.1
Varenhorst, C.2
James, S.3
-
16
-
-
33745699564
-
The platelet inhibitory effects and pharmacokinetics of prasugrel after administration of loading and maintenance doses in healthy subjects
-
DOI 10.1097/01.fjc.0000210069.47205.c0, PII 0000534420060300000007
-
Jakubowski JA, Payne CD, Brandt JT, et al. The platelet inhibitory effects and pharmacokinetics of prasugrel after administration of loading and maintenancedosesinhealthy subjects. J Cardiovasc Pharmacol. 2006;47: 377-384. (Pubitemid 44309690)
-
(2006)
Journal of Cardiovascular Pharmacology
, vol.47
, Issue.3
, pp. 377-384
-
-
Jakubowski, J.A.1
Payne, C.D.2
Brandt, J.T.3
Weerakkody, G.J.4
Farid, N.A.5
Small, D.S.6
Naganuma, H.7
Li, G.Y.8
Winters, K.J.9
-
17
-
-
33845451677
-
A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation
-
Brandt JT, Payne CD, Wiviott SD, et al. A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation. Am Heart J. 2007;153: 66-16.
-
(2007)
Am Heart J.
, vol.153
, pp. 66-16
-
-
Brandt, J.T.1
Payne, C.D.2
Wiviott, S.D.3
-
18
-
-
57149084688
-
Effect of atorvastatin on the pharmacokinetics and pharmacodynamics ofprasugrel and clopidogrel in healthy subjects
-
Farid NA, Small DS, Payne CD, et al. Effect of atorvastatin on the pharmacokinetics and pharmacodynamics ofprasugrel and clopidogrel in healthy subjects. Pharmacotherapy. 2008;28:1483-1494.
-
(2008)
Pharmacotherapy.
, vol.28
, pp. 1483-1494
-
-
Farid, N.A.1
Small, D.S.2
Payne, C.D.3
-
19
-
-
37349111065
-
Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: The prasugrel in comparison to clopidogrel for inhibition of platelet activation and aggregation-thrombolysis in myocardial infarction 44 trial
-
DOI 10.1161/CIRCULATIONAHA.107.740324
-
Wiviott SD, Trenk D, Frelinger AL, et al; PRINCIPLE-TIMI 44 Investigators. Prasugrel compared with high loading-and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial. Circulation. 2007;116:2923-2932. (Pubitemid 350291199)
-
(2007)
Circulation
, vol.116
, Issue.25
, pp. 2923-2932
-
-
Wiviott, S.D.1
Trenk, D.2
Frelinger, A.L.3
O'Donoghue, M.4
Neumann, F.-J.5
Michelson, A.D.6
Angiolillo, D.J.7
Hod, H.8
Montalescot, G.9
Miller, D.L.10
Jakubowski, J.A.11
Cairns, R.12
Murphy, S.A.13
McCabe, C.H.14
Antman, E.M.15
Braunwald, E.16
-
20
-
-
50249184573
-
Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel
-
Small DS, Farid NA, Li YG, et al. Effect of ranitidine on the pharmacokinetics and pharmacodynamics of prasugrel and clopidogrel. Curr Med Res Opin. 2008;24:2251-2257.
-
(2008)
Curr Med Res Opin.
, vol.24
, pp. 2251-2257
-
-
Small, D.S.1
Farid, N.A.2
Li, Y.G.3
-
21
-
-
78650293730
-
Comparison ofprasugrel with clopidogrel on platelet function in coronary artery disease patients with type 2 diabetes mellitus\Third Optimizing Anti-Platelet Therapy in Diabetes Mellit US (OPTIMUS-3)
-
abstract 4946
-
Angiolillo DJ, Badimon J, Saucedo JF, et al. Comparison ofprasugrel with clopidogrel on platelet function in coronary artery disease patients with type 2 diabetes mellitus\Third Optimizing Anti-Platelet Therapy in Diabetes Mellit US (OPTIMUS-3). Circulation. 2009;120:S1027; abstract 4946.
-
(2009)
Circulation.
, vol.120
-
-
Angiolillo, D.J.1
Badimon, J.2
Saucedo, J.F.3
-
22
-
-
79953817883
-
Integrated analysis of pharmacokinetic data across multiple clinical pharmacology studies of prasugrel, a new thienopyridine antiplatelet agent
-
April 2. [Epub ahead of print]
-
Small DS, Li YG, Ernest CS, et al. Integrated analysis of pharmacokinetic data across multiple clinical pharmacology studies of prasugrel, a new thienopyridine antiplatelet agent. J Clin Pharmacol. 2010, April 2. [Epub ahead of print].
-
J Clin Pharmacol.
, vol.2010
-
-
Small, D.S.1
Li, Y.G.2
Ernest, C.S.3
-
23
-
-
33947284488
-
12 inhibitor, compared with clopidogrel in healthy humans
-
DOI 10.1111/j.1365-2125.2006.02792.x
-
12 inhibitor, compared with clopidogrel in healthy humans. Br J Clin Pharmacol. 2007;63: 421-430. (Pubitemid 46426638)
-
(2007)
British Journal of Clinical Pharmacology
, vol.63
, Issue.4
, pp. 421-430
-
-
Jakubowski, J.A.1
Matsushima, N.2
Asai, F.3
Naganuma, H.4
Brandt, J.T.5
Hirota, T.6
Freestone, S.7
Winters, K.J.8
-
25
-
-
79953814864
-
-
Available at Accessed May 11, 2010
-
Effient [package insert]. Available at: http://pi.lilly.com/us/effient. pdf. Accessed May 11, 2010.
-
Effient [Package Insert]
-
-
-
26
-
-
34447271701
-
Comparison of Speed of Onset of Platelet Inhibition After Loading Doses of Clopidogrel Versus Prasugrel in Healthy Volunteers and Correlation With Responder Status
-
DOI 10.1016/j.amjcard.2007.02.103, PII S000291490700728X
-
Weerakkody GJ, Jakubowski JA, Brandt JT, et al. Comparison of speed of onset of platelet inhibition after loading doses of clopidogrel versus prasugrel in healthy volunteers and correlation with responder status. Am J Cardiol. 2007;100:331-336. (Pubitemid 47042002)
-
(2007)
American Journal of Cardiology
, vol.100
, Issue.2
, pp. 331-336
-
-
Weerakkody, G.J.1
Jakubowski, J.A.2
Brandt, J.T.3
Farid, N.A.4
Payne, C.D.5
Zhu, J.6
Warner, M.R.7
Naganuma, H.8
Winters, K.J.9
-
27
-
-
77950508416
-
Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: The RESPOND study
-
Gurbel PA, Bliden KP, Butler K, et al. Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study. Circulation. 2010;121:1188-1199.
-
(2010)
Circulation.
, vol.121
, pp. 1188-1199
-
-
Gurbel, P.A.1
Bliden, K.P.2
Butler, K.3
-
28
-
-
0037145863
-
Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: A randomized controlled trial
-
DOI 10.1001/jama.288.19.2411
-
Steinhubl SR, Berger PB, Mann JT III, et al; CREDO Investigators. Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial. JAMA. 2002;288: 2411-2420. (Pubitemid 35340537)
-
(2002)
Journal of the American Medical Association
, vol.288
, Issue.19
, pp. 2411-2420
-
-
Steinhubl, S.R.1
Berger, P.B.2
Tift Mann III, J.3
Fry, E.T.A.4
DeLago, A.5
Wilmer, C.6
Topol, E.J.7
-
29
-
-
33846656039
-
Platelet response to clopidogrel is attenuated in diabetic patients undergoing coronary stent implantation
-
DOI 10.2337/dc06-1625
-
Geisler T, Anders N, Paterok M, et al. Platelet response to clopidogrel is attenuated in diabetic patients undergoing coronary stent implantation. Diabetes Care. 2007;30:372-374. (Pubitemid 46198349)
-
(2007)
Diabetes Care
, vol.30
, Issue.2
, pp. 372-374
-
-
Geisler, T.1
Anders, N.2
Paterok, M.3
Langer, H.4
Stellos, K.5
Lindemann, S.6
Herdeg, C.7
May, A.E.8
Gawaz, M.9
-
30
-
-
23644433510
-
Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment
-
DOI 10.2337/diabetes.54.8.2430
-
Angiolillo DJ, Fernandez-Ortiz A, Bernardo E, et al. Platelet function profiles in patients with type 2 diabetes and coronary artery disease on combined aspirin and clopidogrel treatment. Diabetes. 2005;54: 2430-2435. (Pubitemid 41134272)
-
(2005)
Diabetes
, vol.54
, Issue.8
, pp. 2430-2435
-
-
Angiolillo, D.J.1
Fernandez-Ortiz, A.2
Bernardo, E.3
Ramirez, C.4
Sabate, M.5
Jimenez-Quevedo, P.6
Hernandez, R.7
Moreno, R.8
Escaned, J.9
Alfonso, F.10
Banuelos, C.11
Costa, M.A.12
Bass, T.A.13
Macaya, C.14
|