Tyrosine kinase A receptor (trkA): A potential marker in epithelial ovarian cancer

Gynecologic Oncology

Volumn 121, Issue 1, 2011, Pages 13-23

  Tapia, Verónica ^a   Gabler, Fernando ^b   Muñoz, Marcela ^a   Yazigi, Roberto ^c   Paredes, Alfonso ^b   Selman, Alberto ^b   Vega, Margarita ^a,b   Romero, Carmen ^a,b  

^a HOSPITAL CLÍNICO UNIVERSIDAD DE CHILE   (Chile)

^b UNIVERSITY OF CHILE   (Chile)

^c CLÍNICA LAS CONDES   (Chile)

Author keywords

Epithelial ovarian cancer; NGF; p trkA; trkA; VEGF

Indexed keywords

NERVE GROWTH FACTOR; PROTEIN TYROSINE KINASE A; VASCULOTROPIN;

ADULT; AGED; ANGIOGENESIS; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENDOTHELIUM CELL; EPITHELIAL OVARY CANCER; EPITHELIUM CELL; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; OVARY CANCER; PRIORITY JOURNAL; PROTEIN SECRETION;

AGED; CELL DIFFERENTIATION; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CELL MOVEMENT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MIDDLE AGED; NEOPLASMS, GLANDULAR AND EPITHELIAL; NERVE GROWTH FACTOR; OVARIAN NEOPLASMS; RECEPTOR, TRKA; RNA, MESSENGER; TUMOR MARKERS, BIOLOGICAL; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 79952817307     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2010.12.341     Document Type: Article

References (22)

1. Auersperg N, Ota T, Mitchell GW. Early events in ovarian epithelial carcinogenesis: progress and problems in experimental approaches. Int J Gynecol Cancer 2002;12:691-703. (Pubitemid 35388036)
2. Jordan S, Green A, Webb P. Benign epithelial ovarian tumors-cancer precursors or markers for ovarian cancer risk? Cancer Causes Control 2006;17:623-32.
3. Auersperg N, Wong A, Choi K-C, Kang SK, Leung P. Ovarian surface epithelium: biology, endocrinology and pathology. Endocr Rev 2001;22:255-88. (Pubitemid 32458162)
4. Descamps S, Toillon R, Adriaenssens E, Pawlowski V, Cool SM, Nurcombe V, et al. Expression of nerve growth factor receptors and their prognostic value in human breast cancer. Cancer Res 2001;61:4337-40. (Pubitemid 32685755)
5. Dang C, Zhang Y, Ma Q, Shimahara Y. Expression of nerve growth factor receptors is correlated with progression and prognosis of human pancreatic cancer. J Gastroenterol Hepatol 2006;21:850-8. (Pubitemid 43793283)
6. Davidson B, Lazarivici P, Ezersky A, Nesland J, Berner A, Risberg B, et al. Expression levels of the nerve growth factor receptors trkA and p75 in effusions and solid tumors of serous ovarian carcinoma patients. Clin Cancer Res 2001;7:3457-64. (Pubitemid 33069981)
7. Tacconelli A, Farina AR, Cappabianca L, Desantis G, Tessitore A, Vetuschi A, et al. TrKA alternative splicing: a regulated tumor-promoting switch in human neuroblastoma. Cancer Cell 2004;6:347-60. (Pubitemid 39361436)
8. Calzá L, Giardino L, Giuliani A, Aloe L, Levi-Montalcini R. Nerve growth factor control of neuronal expression of angiogenetic and vasoactive factors. PNAS 2001;98:4160-5. (Pubitemid 32249915)
9. Campos X, Muñoz Y, Selman A, Yazigi R, Moyano L, Weinstein-Oppenheimer C, et al. Nerve growth factor and its high-affinity receptor TrkA participate in the control of vascular endothelial growth factor expression in epithelial ovarian cancer. Gynecol Oncol 2007;104:168-75. (Pubitemid 46054119)
10. Julio-Pieper M, Lara H, Bravo J, Romero C. Effects of nerve growth factor (NGF) on blood vessels area and expression of the angiogenic factors VEGF and TGFbeta I in the rat ovary. Reprod Biol Endocrinol 2006;4:57-67.
11. Julio-Pieper M, Lozada P, Tapia V, Vega M, Miranda C, Vantman D, et al. Nerve growth factor induces vascular endotelial growth factor expression in granulosa cells via a trkA receptor/mitogen-activated protein kinase - extracellularly regulated kinase 2-dependent pathway. J Clin Endocrinol Metab 2009;94(8):3065-71.
12. Ødegaard E, Staff A, Abeler V, Kopolovic J, Onsrud M, Lazarovici P, et al. The activated nerve growth factor receptor p-TrKA is selectively expressed in advanced-stage ovarian carcinoma. Hum Pathol 2007;38:140-6.
13. Salas C, Julio-Pieper M, Valladares M, Pommer R, Vega M, Mastronardi C, et al. Nerve growth factor-dependent activation of trkA receptors in the human ovary results in synthesis of follicle-stimulating hormone receptors and estrogen secretion. J Clin Endocrinol Metab 2006;91:2396-403. (Pubitemid 43855033)
14. Bauer J, Margolis M, Schreiner C, Edgell CJ, Azizkhan J, Lazaeowski E, et al. In vitro model of angiogenesis using a human endothelium-derived permanent cell line: contributions of induced gene expression, G-proteins, and integrins. J Cell Physiol 1992;153:437-49.
15. Hamilton TC, Young RC, Ozols RF. Experimental model systems of ovarian cancer: applications to the design and evaluation of new treatment approaches. Semin Oncol 1984;11:285-98. (Pubitemid 14013135)
16. Aranda E, Owen GI. A semi-quantitative assay to screen for angiogenic compounds and compounds with angiogenic potential using the EA.hy926 endothelial cell line. Biol Res 2009;42:377-89.
17. Lagadec C, Meignan S, Adriaenssens E, Foveau B, Vanhecke E, Romon R, et al. TrkA overexpression enhances growth and metastasis of breast cancer cells. Oncogene 2009;28:1960-70.
18. Davidson B, Reich R, Lazarovici P, Nesland JM, Skrede M, Risberg B, et al. Expression and activation of the nerve growth factor receptor TrkA in serous ovarian carcinoma. Clin Cancer Res 2003;9:2248-59. (Pubitemid 36687650)
19. Brown MR, Blanchette JO, Kohn EC. Angiogenesis in ovarian cancer. Baillières Best Pract Res Clin Obstet Gynaecol 2000;14(6):901-18. (Pubitemid 32123680)
20. Hazelton DA, Hamilton TC. Vascular endothelial growth factor in ovarian cancer. Curr Oncol Rep 1999;1(1):59-63.
21. Papetti M, Herman IM. Mechanisms of normal and tumor-derived angiogenesis. Am J Physiol Cell Physiol 2002;282:C947-70.
22. Masood R, Cai J, Zheng T, Smith DL, Hinton DR, Gill PS. Vascular endothelial growth factor (VEGF) is an autocrine growth factor for VEGF receptor positive human tumors. Blood 2001;98:1904-13.