Efficient dehydration of aldoximes to nitriles catalyzed by a Lewis acid ionic liquid

Chemistry Letters

Volumn 40, Issue 4, 2011, Pages 396-397

  Nakajima, Mizuki ^a   Qiao, Kun ^a   Kobayashi, Nobuhisa ^a   Bao, Quanxi ^a   Tomida, Daisuke ^a   Yokoyama, Chiaki ^a  

^a TOHOKU UNIVERSITY   (Japan)

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Indexed keywords

EID: 79952807160     PISSN: 03667022     EISSN: 13480715     Source Type: Journal    
DOI: 10.1246/cl.2011.396     Document Type: Article

References (15)

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13. The typical experimental procedure for dehydration of aldoximes to nitriles in the presence of acidic ionic liquid was as follows: aldoxime (2.85mmol), solvent (3.0g), and ionic liquid (20% equiv) were placed in a 10mL glass test tube. Then the reaction was allowed to proceed at 100 °C for the desired time. After the reaction was finished, the upper phase was analyzed by a gas chromatograph (Shimadzu GC-2014) equipped with a flame ionization detector and an ULBON HR-52 capillary column (25m × 0.32mm i.d., Shinwa Chemical Industries Ltd., Japa . Toluene was used as an internal standard.
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15. Supporting Information is available electronically on the CSJ-Journal Web site, http://www.csj.jp/journals/chem-lett/index.html.