-
1
-
-
0033565561
-
The biology of chronic myeloid leukemia
-
DOI 10.1056/NEJM199907153410306
-
Faderl S, Talpaz M, Estrov Z, et al. The biology of chronic myeloid leukemia. N Engl J Med 1999;341:164-172. (Pubitemid 29325745)
-
(1999)
New England Journal of Medicine
, vol.341
, Issue.3
, pp. 164-172
-
-
Faderl, S.1
Talpaz, M.2
Estrov, Z.3
O'Brien, S.4
Kurzrock, R.5
Kantarjian, H.M.6
-
2
-
-
33644525274
-
Gene expression changes associated with progression and response in chronic myeloid leukemia
-
Radich JP, Dai H, Mao M, et al. Gene expression changes associated with progression and response in chronic myeloid leukemia. Proc Natl Acad Sci U S A 2006;103:2794-2799.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 2794-2799
-
-
Radich, J.P.1
Dai, H.2
Mao, M.3
-
3
-
-
0033614446
-
Chronic myeloid leukemia
-
DOI 10.1056/NEJM199904293401706
-
Sawyers CL. Chronic myeloid leukemia. N Engl J Med 1999;340:1330-1340. (Pubitemid 29196596)
-
(1999)
New England Journal of Medicine
, vol.340
, Issue.17
, pp. 1330-1340
-
-
Sawyers, C.L.1
-
4
-
-
10744233716
-
Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia
-
DOI 10.1056/NEJMoa022457
-
O'Brien SG, Guilhot F, Larson RA, et al. Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2003;348:994-1004. (Pubitemid 36302244)
-
(2003)
New England Journal of Medicine
, vol.348
, Issue.11
, pp. 994-1004
-
-
O'Brien, S.G.1
Guilhot, F.2
Larson, R.A.3
Gathmann, I.4
Baccarani, M.5
Cervantes, F.6
Cornelissen, J.J.7
Fischer, T.8
Hochhaus, A.9
Hughes, T.10
Lechner, K.11
Nielsen, J.L.12
Rousselot, P.13
Reiffers, J.14
Saglio, G.15
Shepherd, J.16
Simonsson, B.17
Gratwohl, A.18
Goldman, J.M.19
Kantarjian, H.20
Taylor, K.21
Verhoef, G.22
Bolton, A.E.23
Capdeville, R.24
Druker, B.J.25
more..
-
5
-
-
33845444046
-
Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia
-
DOI 10.1056/NEJMoa062867
-
Druker BJ, Guilhot F, O'Brien SG, et al. Five-year follow-up of patients receiving imatinib for chronic myeloid leukemia. N Engl J Med 2006;355:2408-2417. (Pubitemid 44903745)
-
(2006)
New England Journal of Medicine
, vol.355
, Issue.23
, pp. 2408-2417
-
-
Druker, B.J.1
Guilhot, F.2
O'Brien, S.G.3
Gathmann, I.4
Kantarjian, H.5
Gattermann, N.6
Deininger, M.W.N.7
Silver, R.T.8
Goldman, J.M.9
Stone, R.M.10
Cervantes, F.11
Hochhaus, A.12
Powell, B.L.13
Gabrilove, J.L.14
Rousselot, P.15
Reiffers, J.16
Cornelissen, J.J.17
Hughes, T.18
Agis, H.19
Fischer, T.20
Verhoef, G.21
Shepherd, J.22
Saglio, G.23
Gratwohl, A.24
Nielsen, J.L.25
Radich, J.P.26
Simonsson, B.27
Taylor, K.28
Baccarani, M.29
So, C.30
Letvak, L.31
Larson, R.A.32
more..
-
6
-
-
77949767505
-
International randomized study of interferon vs STI571 (IRIS) 8-year follow up: Sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib
-
abstract Abstract 1126
-
Deininger M, O'Brien SG, Guilhot F, et al. International randomized study of interferon vs STI571 (IRIS) 8-year follow up: sustained survival and low risk for progression or events in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib [abstract]. Blood 2009;114:Abstract 1126.
-
(2009)
Blood
, vol.114
-
-
Deininger, M.1
O'Brien, S.G.2
Guilhot, F.3
-
7
-
-
73149122765
-
High rates of durable response are achieved with imatinib after treatment with interferon alpha plus cytarabine: Results from the International Randomized Study of Interferon and STI571 (IRIS) trial
-
Guilhot F, Druker B, Larson RA, et al. High rates of durable response are achieved with imatinib after treatment with interferon alpha plus cytarabine: results from the International Randomized Study of Interferon and STI571 (IRIS) trial. Haematologica 2009;94:1669-1675.
-
(2009)
Haematologica
, vol.94
, pp. 1669-1675
-
-
Guilhot, F.1
Druker, B.2
Larson, R.A.3
-
8
-
-
33646482407
-
Altered bone and mineral metabolism in patients receiving imatinib mesylate
-
Berman E, Nicolaides M, Maki RG, et al. Altered bone and mineral metabolism in patients receiving imatinib mesylate. N Engl J Med 2006;354:2006-2013.
-
(2006)
N Engl J Med
, vol.354
, pp. 2006-2013
-
-
Berman, E.1
Nicolaides, M.2
Maki, R.G.3
-
9
-
-
33746845181
-
Cardiotoxicity of the cancer therapeutic agent imatinib mesylate
-
DOI 10.1038/nm1446, PII NM1446
-
Kerkela R, Grazette L, Yacobi R, et al. Cardiotoxicity of the cancer therapeutic agent imatinib mesylate. Nat Med 2006;12:908-916. (Pubitemid 44175142)
-
(2006)
Nature Medicine
, vol.12
, Issue.8
, pp. 908-916
-
-
Kerkela, R.1
Grazette, L.2
Yacobi, R.3
Iliescu, C.4
Patten, R.5
Beahm, C.6
Walters, B.7
Shevtsov, S.8
Pesant, S.9
Clubb, F.J.10
Rosenzweig, A.11
Salomon, R.N.12
Van Etten, R.A.13
Alroy, J.14
Durand, J.-B.15
Force, T.16
-
10
-
-
34548030470
-
Congestive heart failure is a rare event in patients receiving imatinib therapy
-
DOI 10.1182/blood-2007-01-070144
-
Atallah E, Durand JB, Kantarjian H, Cortes J. Congestive heart failure is a rare event in patients receiving imatinib therapy. Blood 2007;110:1233-1237. (Pubitemid 47281421)
-
(2007)
Blood
, vol.110
, Issue.4
, pp. 1233-1237
-
-
Atallah, E.1
Durand, J.-B.2
Kantarjian, H.3
Cortes, J.4
-
11
-
-
11144354274
-
High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome-positive chronic phase chronic myeloid leukemia
-
DOI 10.1182/blood-2003-11-3800
-
Kantarjian H, Talpaz M, O'Brien S, et al. High-dose imatinib mesylate therapy in newly diagnosed Philadelphia chromosome- positive chronic phase chronic myeloid leukemia. Blood 2004;103:2873-2878. (Pubitemid 38451654)
-
(2004)
Blood
, vol.103
, Issue.8
, pp. 2873-2878
-
-
Kantarjian, H.1
Talpaz, M.2
O'Brien, S.3
Garcia-Manero, G.4
Verstovsek, S.5
Giles, F.6
Rios, M.B.7
Shan, J.8
Letvak, L.9
Thomas, D.10
Faderl, S.11
Ferrajoli, A.12
Cortes, J.13
-
12
-
-
70350442594
-
High-dose imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: High rates of rapid cytogenetic and molecular responses
-
Cortes JE, Kantarjian HM, Goldberg SL, et al. High-dose imatinib in newly diagnosed chronic-phase chronic myeloid leukemia: high rates of rapid cytogenetic and molecular responses. J Clin Oncol 2009;27:4754-4759.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4754-4759
-
-
Cortes, J.E.1
Kantarjian, H.M.2
Goldberg, S.L.3
-
13
-
-
58149160055
-
Impact of early dose intensity on cytogenetic and molecular responses in chronic-phase CML patients receiving 600 mg/day of imatinib as initial therapy
-
Hughes TP, Branford S, White DL, et al. Impact of early dose intensity on cytogenetic and molecular responses in chronic-phase CML patients receiving 600 mg/day of imatinib as initial therapy. Blood 2008;112:3965-3973.
-
(2008)
Blood
, vol.112
, pp. 3965-3973
-
-
Hughes, T.P.1
Branford, S.2
White, D.L.3
-
14
-
-
65349140717
-
Results of high-dose imatinib mesylate in intermediate Sokal risk chronic myeloid leukemia patients in early chronic phase: A phase 2 trial of the GIMEMA CML Working Party
-
Castagnetti F, Palandri F, Amabile M, et al. Results of high-dose imatinib mesylate in intermediate Sokal risk chronic myeloid leukemia patients in early chronic phase: a phase 2 trial of the GIMEMA CML Working Party. Blood 2009;113:3428-3434.
-
(2009)
Blood
, vol.113
, pp. 3428-3434
-
-
Castagnetti, F.1
Palandri, F.2
Amabile, M.3
-
15
-
-
66549108340
-
Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia-positive chronic myeloid leukemia: A European LeukemiaNet Study
-
Baccarani M, Rosti G, Castagnetti F, et al. Comparison of imatinib 400 mg and 800 mg daily in the front-line treatment of high-risk, Philadelphia- positive chronic myeloid leukemia: a European LeukemiaNet Study. Blood 2009;113:4497-4504.
-
(2009)
Blood
, vol.113
, pp. 4497-4504
-
-
Baccarani, M.1
Rosti, G.2
Castagnetti, F.3
-
16
-
-
75749105885
-
Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: Tyrosine kinase inhibitor optimization and selectivity study
-
Cortes JE, Baccarani M, Guilhot F, et al. Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study. J Clin Oncol 2010;28:424-430.
-
(2010)
J Clin Oncol
, vol.28
, pp. 424-430
-
-
Cortes, J.E.1
Baccarani, M.2
Guilhot, F.3
-
17
-
-
79951487543
-
Treatment optimization by high-dose imatinib: Randomized comparison of imatinib 800 mg versus imatinib 400 mg {+/-} IFN in newly diagnosed BCR-ABL positive chronic phase (CP) CML: The German CML-study IV
-
abstract Abstract 6517
-
Hehlmann R, Lauseker M, Jung-Munkwitz S, et al. Treatment optimization by high-dose imatinib: randomized comparison of imatinib 800 mg versus imatinib 400 mg {+/-} IFN in newly diagnosed BCR-ABL positive chronic phase (CP) CML: the German CML-study IV [abstract]. J Clin Oncol 2010;28(Suppl 1):Abstract 6517.
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL. 1
-
-
Hehlmann, R.1
Lauseker, M.2
Jung-Munkwitz, S.3
-
18
-
-
3142676436
-
Overriding imatinib resistance with a novel ABL kinase inhibitor
-
DOI 10.1126/science.1099480
-
Shah NP, Tran C, Lee FY, et al. Overriding imatinib resistance with a novel ABL kinase inhibitor. Science 2004;305:399-401. (Pubitemid 38938156)
-
(2004)
Science
, vol.305
, Issue.5682
, pp. 399-401
-
-
Shah, N.P.1
Tran, C.2
Lee, F.Y.3
Chen, P.4
Norris, D.5
Sawyers, C.L.6
-
19
-
-
75749129911
-
Results of dasatinib therapy in patients with early chronic-phase chronic myeloid leukemia
-
Cortes JE, Jones D, O'Brien S, et al. Results of dasatinib therapy in patients with early chronic-phase chronic myeloid leukemia. J Clin Oncol 2010;28:398-404.
-
(2010)
J Clin Oncol
, vol.28
, pp. 398-404
-
-
Cortes, J.E.1
Jones, D.2
O'Brien, S.3
-
20
-
-
77953725855
-
Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia
-
Kantarjian H, Shah NP, Hochhaus A, et al. Dasatinib versus imatinib in newly diagnosed chronic-phase chronic myeloid leukemia. N Engl J Med 2010;362:2260-2270.
-
(2010)
N Engl J Med
, vol.362
, pp. 2260-2270
-
-
Kantarjian, H.1
Shah, N.P.2
Hochhaus, A.3
-
21
-
-
79952038795
-
Dasatinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) in the DASISION trial: 18-month follow-up
-
abstract Abstract 206
-
Shah N, Kantarjian H, Hochhaus A, et al. Dasatinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) in the DASISION trial: 18-month follow-up [abstract]. Blood 2010;116:Abstract 206.
-
(2010)
Blood
, vol.116
-
-
Shah, N.1
Kantarjian, H.2
Hochhaus, A.3
-
22
-
-
79952787880
-
A randomized phase II trial of dasatinib 100 mg vs imatinib 400 mg in newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): The S0325 Intergroup trial
-
abstract Abstract LBA-6
-
Radich JP, Kopecky KJ, Kamel-Reid S, et al. A randomized phase II trial of dasatinib 100 mg vs imatinib 400 mg in newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP): the S0325 Intergroup trial [abstract]. Blood 2010;116:Abstract LBA-6.
-
(2010)
Blood
, vol.116
-
-
Radich, J.P.1
Kopecky, K.J.2
Kamel-Reid, S.3
-
23
-
-
13844251975
-
Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl
-
DOI 10.1016/j.ccr.2005.01.007
-
Weisberg E, Manley PW, Breitenstein W, et al. Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl. Cancer Cell 2005;7:129-141. (Pubitemid 40248339)
-
(2005)
Cancer Cell
, vol.7
, Issue.2
, pp. 129-141
-
-
Weisberg, E.1
Manley, P.W.2
Breitenstein, W.3
Bruggen, J.4
Cowan-Jacob, S.W.5
Ray, A.6
Huntly, B.7
Fabbro, D.8
Fendrich, G.9
Hall-Meyers, E.10
Kung, A.L.11
Mestan, J.12
Daley, G.Q.13
Callahan, L.14
Catley, L.15
Cavazza, C.16
Mohammed, A.17
Neuberg, D.18
Wright, R.D.19
Gilliland, D.G.20
Griffin, J.D.21
more..
-
24
-
-
75749090051
-
Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase
-
Cortes JE, Jones D, O'Brien S, et al. Nilotinib as front-line treatment for patients with chronic myeloid leukemia in early chronic phase. J Clin Oncol 2010;28:392-397.
-
(2010)
J Clin Oncol
, vol.28
, pp. 392-397
-
-
Cortes, J.E.1
Jones, D.2
O'Brien, S.3
-
25
-
-
73949145209
-
Nilotinib for the frontline treatment of Ph+ chronic myeloid leukemia
-
Rosti G, Palandri F, Castagnetti F, et al. Nilotinib for the frontline treatment of Ph+ chronic myeloid leukemia. Blood 2009;114:4933-4938.
-
(2009)
Blood
, vol.114
, pp. 4933-4938
-
-
Rosti, G.1
Palandri, F.2
Castagnetti, F.3
-
26
-
-
77953691179
-
Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia
-
Saglio G, Kim DW, Issaragrisil S, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. N Engl J Med 2010;362:2251-2259.
-
(2010)
N Engl J Med
, vol.362
, pp. 2251-2259
-
-
Saglio, G.1
Kim, D.W.2
Issaragrisil, S.3
-
27
-
-
79952038063
-
ENESTnd update: Continued superiority of nilotinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP)
-
abstract Abstract 207
-
Hughes TP, Hochhaus A, Saglio G, et al. ENESTnd update: continued superiority of nilotinib versus imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase (CML-CP) [abstract]. Blood 2010;116:Abstract 207.
-
(2010)
Blood
, vol.116
-
-
Hughes, T.P.1
Hochhaus, A.2
Saglio, G.3
-
28
-
-
49149111543
-
Imatinib for newly diagnosed patients with chronic myeloid leukemia: Incidence of sustained responses in an intention-to-treat analysis
-
de Lavallade H, Apperley JF, Khorashad JS, et al. Imatinib for newly diagnosed patients with chronic myeloid leukemia: incidence of sustained responses in an intention-to-treat analysis. J Clin Oncol 2008;26:3358-3363.
-
(2008)
J Clin Oncol
, vol.26
, pp. 3358-3363
-
-
De Lavallade, H.1
Apperley, J.F.2
Khorashad, J.S.3
-
29
-
-
20944442975
-
Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate
-
DOI 10.1158/1078-0432.CCR-04-2139
-
Cortes J, Talpaz M, O'Brien S, et al. Molecular responses in patients with chronic myelogenous leukemia in chronic phase treated with imatinib mesylate. Clin Cancer Res 2005;11:3425-3432. (Pubitemid 40627896)
-
(2005)
Clinical Cancer Research
, vol.11
, Issue.9
, pp. 3425-3432
-
-
Cortes, J.1
Talpaz, M.2
O'Brien, S.3
Jones, D.4
Luthra, R.5
Shan, J.6
Giles, F.7
Faderl, S.8
Verstovsek, S.9
Garcia-Manero, G.10
Rios, M.B.11
Kantarjian, H.12
-
30
-
-
33744798191
-
Achieving a major molecular response at the time of a complete cytogenetic response (CCgR) predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients
-
DOI 10.1158/1078-0432.CCR-05-2574
-
Iacobucci I, Saglio G, Rosti G, et al. Achieving a major molecular response at the time of a complete cytogenetic response (CCgR) predicts a better duration of CCgR in imatinib-treated chronic myeloid leukemia patients. Clin Cancer Res 2006;12:3037-3042. (Pubitemid 43837348)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.10
, pp. 3037-3042
-
-
Iacobucci, I.1
Saglio, G.2
Rosti, G.3
Testoni, N.4
Pane, F.5
Amabile, M.6
Poerio, A.7
Soverini, S.8
Bassi, S.9
Cilloni, D.10
Bassan, R.11
Breccia, M.12
Lauria, F.13
Izzo, B.14
Merante, S.15
Frassoni, F.16
Paolini, S.17
Montefusco, E.18
Baccarani, M.19
Martinelli, G.20
more..
-
31
-
-
77958595179
-
Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: An analysis from the International Randomized Study of Interferon and STI571 (IRIS)
-
Hughes TP, Hochhaus A, Branford S, et al. Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS). Blood 2010;116:3758-3765.
-
(2010)
Blood
, vol.116
, pp. 3758-3765
-
-
Hughes, T.P.1
Hochhaus, A.2
Branford, S.3
-
32
-
-
18144451171
-
Chronic myeloid leukemia and interferon-alpha: A study of complete cytogenetic responders
-
Bonifazi F, de Vivo A, Rosti G, et al. Chronic myeloid leukemia and interferon-alpha: a study of complete cytogenetic responders. Blood 2001;98:3074-3081.
-
(2001)
Blood
, vol.98
, pp. 3074-3081
-
-
Bonifazi, F.1
De Vivo, A.2
Rosti, G.3
-
33
-
-
0037441629
-
Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis
-
DOI 10.1002/cncr.11223
-
Kantarjian HM, O'Brien S, Cortes JE, et al. Complete cytogenetic and molecular responses to interferon-alpha-based therapy for chronic myelogenous leukemia are associated with excellent long-term prognosis. Cancer 2003;97:1033-1041. (Pubitemid 36173155)
-
(2003)
Cancer
, vol.97
, Issue.4
, pp. 1033-1041
-
-
Kantarjian, H.M.1
O'Brien, S.2
Cortes, J.E.3
Shan, J.4
Giles, F.J.5
Rios, M.B.6
Faderl, S.H.7
Wierda, W.G.8
Ferrajoli, A.9
Verstovsek, S.10
Keating, M.J.11
Freireich, E.J.12
Talpaz, M.13
-
34
-
-
0036137923
-
Follow-up of complete cytogenetic remission in patients with chronic myeloid leukemia after cessation of interferon alfa
-
DOI 10.1200/JCO.20.1.214
-
Mahon FX, Delbrel X, Cony-Makhoul P, et al. Follow-up of complete cytogenetic remission in patients with chronic myeloid leukemia after cessation of interferon alfa. J Clin Oncol 2002;20:214-220. (Pubitemid 34032614)
-
(2002)
Journal of Clinical Oncology
, vol.20
, Issue.1
, pp. 214-220
-
-
Mahon, F.X.1
Delbrel, X.2
Cony-Makhoul, P.3
Faberes, C.4
Boiron, J.M.5
Barthe, C.6
Bilhou-Nabera, C.7
Pigneux, A.8
Marit, G.9
Reiffers, J.10
-
35
-
-
33745102555
-
Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
DOI 10.1056/NEJMoa055229
-
Talpaz M, Shah NP, Kantarjian H, et al. Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med 2006;354:2531-2541. (Pubitemid 43882349)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.24
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
Donato, N.4
Nicoll, J.5
Paquette, R.6
Cortes, J.7
O'Brien, S.8
Nicaise, C.9
Bleickardt, E.10
Blackwood-Chirchir, M.A.11
Iyer, V.12
Chen, T.-T.13
Huang, F.14
Decillis, A.P.15
Sawyers, C.L.16
-
36
-
-
33947280081
-
Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy
-
DOI 10.1182/blood-2006-09-047266
-
Hochhaus A, Kantarjian HM, Baccarani M, et al. Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy. Blood 2007;109:2303-2309. (Pubitemid 46425867)
-
(2007)
Blood
, vol.109
, Issue.6
, pp. 2303-2309
-
-
Hochhaus, A.1
Kantarjian, H.M.2
Baccarani, M.3
Lipton, J.H.4
Apperley, J.F.5
Druker, B.J.6
Facon, T.7
Goldberg, S.L.8
Cervantes, F.9
Niederwieser, D.10
Silver, R.T.11
Stone, R.M.12
Hughes, T.P.13
Muller, M.C.14
Ezzeddine, R.15
Countouriotis, A.M.16
Shah, N.P.17
-
37
-
-
54949154484
-
Dasatinib 2-year efficacy in patients with chronic-phase chronic myelogenous leukemia (CML-CP) with resistance or intolerance to imatinib (START-C)
-
abstract Abstract 7009
-
Mauro MJ, Baccarani M, Cervantes F, et al. Dasatinib 2-year efficacy in patients with chronic-phase chronic myelogenous leukemia (CML-CP) with resistance or intolerance to imatinib (START-C) [abstract]. J Clin Oncol 2008;26:Abstract 7009.
-
(2008)
J Clin Oncol
, vol.26
-
-
Mauro, M.J.1
Baccarani, M.2
Cervantes, F.3
-
38
-
-
68549140912
-
Dasatinib time to and durability of major and complete cytogenetic response (MCyR and CCyR) in patients with chronic myeloid leukemia in chronic phase (CML-CP)
-
abstract Abstract 450
-
Baccarani M, Rosti G, Saglio G, et al. Dasatinib time to and durability of major and complete cytogenetic response (MCyR and CCyR) in patients with chronic myeloid leukemia in chronic phase (CML-CP) [abstract]. Blood 2008;112:Abstract 450.
-
(2008)
Blood
, vol.112
-
-
Baccarani, M.1
Rosti, G.2
Saglio, G.3
-
39
-
-
77954779639
-
Dasatinib is well-tolerated and efficacious in imatinib-intolerant patients with chronicphase chronic myeloid leukemia (CP-CML)
-
abstract Abstract 1128
-
Khoury HJ, Mauro MJ, Matloub Y, et al. Dasatinib is well-tolerated and efficacious in imatinib-intolerant patients with chronicphase chronic myeloid leukemia (CP-CML) [abstract]. Blood 2009;114:Abstract 1128.
-
(2009)
Blood
, vol.114
-
-
Khoury, H.J.1
Mauro, M.J.2
Matloub, Y.3
-
40
-
-
76549116248
-
Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib
-
Shah NP, Kim DW, Kantarjian H, et al. Potent, transient inhibition of BCR-ABL with dasatinib 100 mg daily achieves rapid and durable cytogenetic responses and high transformation-free survival rates in chronic phase chronic myeloid leukemia patients with resistance, suboptimal response or intolerance to imatinib. Haematologica 2010;95:232-240.
-
(2010)
Haematologica
, vol.95
, pp. 232-240
-
-
Shah, N.P.1
Kim, D.W.2
Kantarjian, H.3
-
41
-
-
70249141675
-
Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: The START A trial
-
Apperley JF, Cortes JE, Kim DW, et al. Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START A trial. J Clin Oncol 2009;27:3472-3479.
-
(2009)
J Clin Oncol
, vol.27
, pp. 3472-3479
-
-
Apperley, J.F.1
Cortes, J.E.2
Kim, D.W.3
-
42
-
-
60049095629
-
Dasatinib efficacy in patients with imatinib-resistant/-intolerant chronic myeloid leukemia in accelerated phase: 24-Month data from START-A
-
abstract. Abstract 0982
-
Rea D, Dombret H, Kim DW, et al. Dasatinib efficacy in patients with imatinib-resistant/-intolerant chronic myeloid leukemia in accelerated phase: 24-month data from START-A [abstract]. Haematologica 2008;93(Suppl 1):Abstract 0982.
-
(2008)
Haematologica
, vol.93
, Issue.SUPPL. 1
-
-
Rea, D.1
Dombret, H.2
Kim, D.W.3
-
43
-
-
57849159300
-
Efficacy and safety of dasatinib in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blast phase
-
Cortes J, Kim DW, Raffoux E, et al. Efficacy and safety of dasatinib in imatinib-resistant or -intolerant patients with chronic myeloid leukemia in blast phase. Leukemia 2008;22:2176-2183.
-
(2008)
Leukemia
, vol.22
, pp. 2176-2183
-
-
Cortes, J.1
Kim, D.W.2
Raffoux, E.3
-
44
-
-
67650607999
-
Phase 3 study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-Month median follow-up
-
Kantarjian H, Cortes J, Kim DW, et al. Phase 3 study of dasatinib 140 mg once daily versus 70 mg twice daily in patients with chronic myeloid leukemia in accelerated phase resistant or intolerant to imatinib: 15-month median follow-up. Blood 2009;113:6322-6329.
-
(2009)
Blood
, vol.113
, pp. 6322-6329
-
-
Kantarjian, H.1
Cortes, J.2
Kim, D.W.3
-
45
-
-
77956823937
-
Dasatinib in imatinib-resistant or imatinib-intolerant chronic myeloid leukemia in blast phase after 2 years of follow-up in a phase 3 study: Efficacy and tolerability of 140 milligrams once daily and 70 milligrams twice daily
-
Saglio G, Hochhaus A, Goh YT, et al. Dasatinib in imatinib-resistant or imatinib-intolerant chronic myeloid leukemia in blast phase after 2 years of follow-up in a phase 3 study: efficacy and tolerability of 140 milligrams once daily and 70 milligrams twice daily. Cancer 2010;116:3852-3861.
-
(2010)
Cancer
, vol.116
, pp. 3852-3861
-
-
Saglio, G.1
Hochhaus, A.2
Goh, Y.T.3
-
46
-
-
33745086350
-
Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL
-
DOI 10.1056/NEJMoa055104
-
Kantarjian H, Giles F, Wunderle L, et al. Nilotinib in imatinib-resistant CML and Philadelphia chromosome-positive ALL. N Engl J Med 2006;354:2542-2551. (Pubitemid 43882350)
-
(2006)
New England Journal of Medicine
, vol.354
, Issue.24
, pp. 2542-2551
-
-
Kantarjian, H.1
Giles, F.2
Wunderle, L.3
Bhalla, K.4
O'Brien, S.5
Wassmann, B.6
Tanaka, C.7
Manley, P.8
Rae, P.9
Mietlowski, W.10
Bochinski, K.11
Hochhaus, A.12
Griffin, J.D.13
Hoelzer, D.14
Albitar, M.15
Dugan, M.16
Cortes, J.17
Alland, L.18
Ottmann, O.G.19
-
47
-
-
36348968931
-
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance
-
DOI 10.1182/blood-2007-03-080689
-
Kantarjian HM, Giles F, Gattermann N, et al. Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome positive chronic myelogenous leukemia in chronic phase following imatinib resistance and intolerance. Blood 2007;110:3540-3546. (Pubitemid 350159618)
-
(2007)
Blood
, vol.110
, Issue.10
, pp. 3540-3546
-
-
Kantarjian, H.M.1
Giles, F.2
Gattermann, N.3
Bhalla, K.4
Alimena, G.5
Palandri, F.6
Ossenkoppele, G.J.7
Nicolini, F.-E.8
O'Brien, S.G.9
Litzow, M.10
Bhatia, R.11
Cervantes, F.12
Haque, A.13
Shou, Y.14
Resta, D.J.15
Weitzman, A.16
Hochhaus, A.17
Le, C.P.18
-
48
-
-
79251546724
-
Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-Month follow-up results
-
Kantarjian HM, Giles FJ, Bhalla KN, et al. Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results. Blood 2011;117:1141-1145.
-
(2011)
Blood
, vol.117
, pp. 1141-1145
-
-
Kantarjian, H.M.1
Giles, F.J.2
Bhalla, K.N.3
-
49
-
-
41349083969
-
Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia
-
DOI 10.1182/blood-2007-04-083196
-
le Coutre P, Ottmann OG, Giles F, et al. Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is active in patients with imatinib-resistant or -intolerant accelerated-phase chronic myelogenous leukemia. Blood 2008;111:1834-1839. (Pubitemid 351451490)
-
(2008)
Blood
, vol.111
, Issue.4
, pp. 1834-1839
-
-
Le, C.P.1
Ottmann, O.G.2
Giles, F.3
Kim, D.-W.4
Cortes, J.5
Gattermann, N.6
Apperley, J.F.7
Larson, R.A.8
Abruzzese, E.9
O'Brien, S.G.10
Kuliczkowski, K.11
Hochhaus, A.12
Mahon, F.-X.13
Saglio, G.14
Gobbi, M.15
Kwong, Y.-L.16
Baccarani, M.17
Hughes, T.18
Martinelli, G.19
Radich, J.P.20
Zheng, M.21
Shou, Y.22
Kantarjian, H.23
more..
-
50
-
-
72149111552
-
Nilotinib in chronic myeloid leukemia patients in accelerated phase (CML-AP) with imatinib (IM) resistance or intolerance: Longer follow-up results of a phase II study
-
abstract Abstract 7057
-
Le Coutre PD, Giles F, Hochhaus A, et al. Nilotinib in chronic myeloid leukemia patients in accelerated phase (CML-AP) with imatinib (IM) resistance or intolerance: longer follow-up results of a phase II study [abstract]. J Clin Oncol 2009;27(Suppl 15):Abstract 7057.
-
(2009)
J Clin Oncol
, vol.27
, Issue.SUPPL. 15
-
-
Le Coutre, P.D.1
Giles, F.2
Hochhaus, A.3
-
51
-
-
78649244836
-
Use of nilotinib to induce responses with 24-month (mo) minimum follow-up in patients (pts) with chronic myeloid leukemia in blast crisis (CML-BC) resistant to or intolerant of imatinib
-
abstract Abstract 6510
-
Giles FJ, Kantarjian H, le Coutre PD, et al. Use of nilotinib to induce responses with 24-month (mo) minimum follow-up in patients (pts) with chronic myeloid leukemia in blast crisis (CML-BC) resistant to or intolerant of imatinib [abstract]. J Clin Oncol 2010;28(Suppl 15):Abstract 6510.
-
(2010)
J Clin Oncol
, vol.28
, Issue.SUPPL. 15
-
-
Giles, F.J.1
Kantarjian, H.2
Le Coutre, P.D.3
-
52
-
-
0037438467
-
Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia
-
DOI 10.1182/blood-2002-05-1451
-
Kantarjian HM, Talpaz M, O'Brien S, et al. Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia. Blood 2003;101:473-475. (Pubitemid 36077567)
-
(2003)
Blood
, vol.101
, Issue.2
, pp. 473-475
-
-
Kantarjian, H.M.1
Talpaz, M.2
O'Brien, S.3
Giles, F.4
Garcia-Manero, G.5
Faded, S.6
Thomas, D.7
Shan, J.8
Rios, M.B.9
Cortes, J.10
-
53
-
-
0141705292
-
Transient benefit only from increasing the imatinib dose in CML patients who do not achieve complete cytogenetic remissions on conventional doses [7] (multiple letters)
-
DOI 10.1182/blood-2003-06-2042
-
Marin D, Goldman JM, Olavarria E, Apperley JF. Transient benefit only from increasing the imatinib dose in CML patients who do not achieve complete cytogenetic remissions on conventional doses. Blood 2003;102:2702-2704. (Pubitemid 37193621)
-
(2003)
Blood
, vol.102
, Issue.7
, pp. 2702-2704
-
-
Marin, D.1
Goldman, J.M.2
Olavarria, E.3
Apperley, J.F.4
Cortes, J.5
Kantarjian, H.6
-
54
-
-
0038176390
-
The effect of dose increase of imatinib mesylate in patients with chronic or accelerated phase chronic myelogenous leukemia with inadequate hematologic or cytogenetic response to initial treatment
-
Zonder JA, Pemberton P, Brandt H, et al. The effect of dose increase of imatinib mesylate in patients with chronic or accelerated phase chronic myelogenous leukemia with inadequate hematologic or cytogenetic response to initial treatment. Clin Cancer Res 2003;9:2092-2097. (Pubitemid 36687630)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.6
, pp. 2092-2097
-
-
Zonder, J.A.1
Pemberton, P.2
Brandt, H.3
Mohamed, A.N.4
Schiffer, C.A.5
-
55
-
-
64049099666
-
Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy
-
Jabbour E, Kantarjian HM, Jones D, et al. Imatinib mesylate dose escalation is associated with durable responses in patients with chronic myeloid leukemia after cytogenetic failure on standard-dose imatinib therapy. Blood 2009;113:2154-2160.
-
(2009)
Blood
, vol.113
, pp. 2154-2160
-
-
Jabbour, E.1
Kantarjian, H.M.2
Jones, D.3
-
56
-
-
60049092698
-
Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase
-
Kantarjian HM, Larson RA, Guilhot F, et al. Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase. Cancer 2009;115:551-560.
-
(2009)
Cancer
, vol.115
, pp. 551-560
-
-
Kantarjian, H.M.1
Larson, R.A.2
Guilhot, F.3
-
57
-
-
34249074686
-
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: A randomized phase 2 trial
-
DOI 10.1182/blood-2006-11-056028
-
Kantarjian H, Pasquini R, Hamerschlak N, et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia after failure of first-line imatinib: a randomized phase 2 trial. Blood 2007;109:5143-5150. (Pubitemid 46890528)
-
(2007)
Blood
, vol.109
, Issue.12
, pp. 5143-5150
-
-
Kantarjian, H.1
Pasquini, R.2
Hamerschlak, N.3
Rousselot, P.4
Holowiecki, J.5
Jootar, S.6
Robak, T.7
Khoroshko, N.8
Masszi, T.9
Skotnicki, A.10
Hellmann, A.11
Zaritsky, A.12
Golenkov, A.13
Radich, J.14
Hughes, T.15
Countouriotis, A.16
Shah, N.17
-
58
-
-
70149105272
-
Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600 milligrams daily: Two-year follow-up of a randomized phase 2 study (START-R)
-
Kantarjian H, Pasquini R, Levy V, et al. Dasatinib or high-dose imatinib for chronic-phase chronic myeloid leukemia resistant to imatinib at a dose of 400 to 600 milligrams daily: two-year follow-up of a randomized phase 2 study (START-R). Cancer 2009;115:4136-4147.
-
(2009)
Cancer
, vol.115
, pp. 4136-4147
-
-
Kantarjian, H.1
Pasquini, R.2
Levy, V.3
-
59
-
-
68249160747
-
Minimal cross-intolerance between nilotinib and imatinib in patients with imatinib-intolerant chronic myeloid leukemia in chronic phase (CML-CP) or accelerated phase (CML-AP)
-
abstract Abstract 3215
-
Jabbour E, Kantarjian HM, Baccarani M, et al. Minimal cross-intolerance between nilotinib and imatinib in patients with imatinib-intolerant chronic myeloid leukemia in chronic phase (CML-CP) or accelerated phase (CML-AP) [abstract]. Blood 2008;112:Abstract 3215.
-
(2008)
Blood
, vol.112
-
-
Jabbour, E.1
Kantarjian, H.M.2
Baccarani, M.3
-
60
-
-
75649105405
-
Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion
-
Porkka K, Khoury HJ, Paquette RL, et al. Dasatinib 100 mg once daily minimizes the occurrence of pleural effusion in patients with chronic myeloid leukemia in chronic phase and efficacy is unaffected in patients who develop pleural effusion. Cancer 2010;116:377-386.
-
(2010)
Cancer
, vol.116
, pp. 377-386
-
-
Porkka, K.1
Khoury, H.J.2
Paquette, R.L.3
-
61
-
-
34548523623
-
Pleural effusion in patients with chronic myelogenous leukemia treated with dasatinib after imatinib failure
-
DOI 10.1200/JCO.2007.12.0329
-
Quintas-Cardama A, Kantarjian H, O'Brien S, et al. Pleural effusion in patients with chronic myelogenous leukemia treated with dasatinib after imatinib failure. J Clin Oncol 2007;25:3908-3914. (Pubitemid 47477268)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.25
, pp. 3908-3914
-
-
Quintas-Cardama, A.1
Kantarjian, H.2
O'Brien, S.3
Borthakur, G.4
Bruzzi, J.5
Munden, R.6
Cortes, J.7
-
62
-
-
68749108104
-
Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy
-
Mustjoki S, Ekblom M, Arstila TP, et al. Clonal expansion of T/NK-cells during tyrosine kinase inhibitor dasatinib therapy. Leukemia 2009;23:1398-1405.
-
(2009)
Leukemia
, vol.23
, pp. 1398-1405
-
-
Mustjoki, S.1
Ekblom, M.2
Arstila, T.P.3
-
63
-
-
79952788297
-
Association of lymphocytosis following treatment with dasatinib with response and outcome
-
abstract Abstract 6553
-
Schiffer CA, Cortes JE, Saglio G, et al. Association of lymphocytosis following treatment with dasatinib with response and outcome [abstract]. J Clin Oncol 2010;28:Abstract 6553.
-
(2010)
J Clin Oncol
, vol.28
-
-
Schiffer, C.A.1
Cortes, J.E.2
Saglio, G.3
-
64
-
-
79952780448
-
Lymphocytosis following first-line treatment for CML in chronic phase with dasatinib is associated with improved responses: A comparison with imatinib
-
abstract Abstract 358
-
Schiffer CA, Cortes JE, Saglio G, et al. Lymphocytosis following first-line treatment for CML in chronic phase with dasatinib is associated with improved responses: a comparison with imatinib [abstract]. Blood 2010;116:Abstract 358.
-
(2010)
Blood
, vol.116
-
-
Schiffer, C.A.1
Cortes, J.E.2
Saglio, G.3
-
65
-
-
74849116614
-
Nilotinib: A second-generation tyrosine kinase inhibitor for chronic myeloid leukemia
-
Breccia M, Alimena G. Nilotinib: a second-generation tyrosine kinase inhibitor for chronic myeloid leukemia. Leuk Res 2010;34:129-134.
-
(2010)
Leuk Res
, vol.34
, pp. 129-134
-
-
Breccia, M.1
Alimena, G.2
-
66
-
-
10744232328
-
Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis
-
DOI 10.1182/blood-2002-09-2896
-
Branford S, Rudzki Z, Walsh S, et al. Detection of BCR-ABL mutations in patients with CML treated with imatinib is virtually always accompanied by clinical resistance, and mutations in the ATP phosphate-binding loop (P-loop) are associated with a poor prognosis. Blood 2003;102:276-283. (Pubitemid 36759665)
-
(2003)
Blood
, vol.102
, Issue.1
, pp. 276-283
-
-
Branford, S.1
Rudzki, Z.2
Walsh, S.3
Parkinson, I.4
Grigg, A.5
Szer, J.6
Taylor, K.7
Herrmann, R.8
Seymour, J.F.9
Arthur, C.10
Joske, D.11
Lynch, K.12
Hughes, T.13
-
67
-
-
33846228789
-
Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: By the GIMEMA working party on chronic myeloid leukemia
-
DOI 10.1158/1078-0432.CCR-06-1516
-
Soverini S, Colarossi S, Gnani A, et al. Contribution of ABL kinase domain mutations to imatinib resistance in different subsets of Philadelphia-positive patients: by the GIMEMA Working Party on Chronic Myeloid Leukemia. Clin Cancer Res 2006;12:7374-7379. (Pubitemid 46095411)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.24
, pp. 7374-7379
-
-
Soverini, S.1
Colarossi, S.2
Gnani, A.3
Rosti, G.4
Castagnetti, F.5
Poerio, A.6
Iacobucci, I.7
Amabile, M.8
Abruzzese, E.9
Orlandi, E.10
Radaelli, F.11
Ciccone, F.12
Tiribelli, M.13
Di, L.R.14
Caracciolo, C.15
Izzo, B.16
Pane, F.17
Saglio, G.18
Baccarani, M.19
Martinelli, G.20
more..
-
68
-
-
47249123747
-
Characteristics and outcomes of patients with chronic myeloid leukemia and T315I mutation following failure of imatinib mesylate therapy
-
Jabbour E, Kantarjian H, Jones D, et al. Characteristics and outcomes of patients with chronic myeloid leukemia and T315I mutation following failure of imatinib mesylate therapy. Blood 2008;112:53-55.
-
(2008)
Blood
, vol.112
, pp. 53-55
-
-
Jabbour, E.1
Kantarjian, H.2
Jones, D.3
-
69
-
-
34548721201
-
Clinical outcome of 27 imatinib mesylate-resistant chronic myelogenous leukemia patients harboring a T315I BCR-ABL mutation
-
DOI 10.3324/haematol.11369
-
Nicolini FE, Hayette S, Corm S, et al. Clinical outcome of 27 imatinib mesylate-resistant chronic myelogenous leukemia patients harboring a T315I BCR-ABL mutation. Haematologica 2007;92:1238-1241. (Pubitemid 350144183)
-
(2007)
Haematologica
, vol.92
, Issue.9
, pp. 1238-1241
-
-
Nicolini, F.E.1
Hayette, S.2
Corm, S.3
Bachy, E.4
Bories, D.5
Tulliez, M.6
Guilhot, F.7
Legros, L.8
Maloisel, F.9
Kiladjian, J.-J.10
Mahon, F.-X.11
Le, Q.-H.12
Michallet, M.13
Roche-Lestienne, C.14
Preudhomme, C.15
-
70
-
-
23044458596
-
ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: A study by the GIMEMA working party on chronic myeloid leukemia
-
DOI 10.1200/JCO.2005.05.531
-
Soverini S, Martinelli G, Rosti G, et al. ABL mutations in late chronic phase chronic myeloid leukemia patients with up-front cytogenetic resistance to imatinib are associated with a greater likelihood of progression to blast crisis and shorter survival: a study by the GIMEMA Working Party on Chronic Myeloid Leukemia. J Clin Oncol 2005;23:4100-4109. (Pubitemid 46211315)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.18
, pp. 4100-4109
-
-
Soverini, S.1
Martinelli, G.2
Rosti, G.3
Bassi, S.4
Amabile, M.5
Poerio, A.6
Giannini, B.7
Trabacchi, E.8
Castagnetti, F.9
Testoni, N.10
Luatti, S.11
De Vivo, A.12
Cilloni, D.13
Izzo, B.14
Fava, M.15
Abruzzese, E.16
Alberti, D.17
Pane, F.18
Saglio, G.19
Baccarani, M.20
more..
-
71
-
-
76249090055
-
Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure: Does the BCR-ABL mutation status really matter?
-
Branford S, Melo JV, Hughes TP. Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure: does the BCR-ABL mutation status really matter? Blood 2009;114:5426-5435.
-
(2009)
Blood
, vol.114
, pp. 5426-5435
-
-
Branford, S.1
Melo, J.V.2
Hughes, T.P.3
-
72
-
-
58549088155
-
Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants
-
Redaelli S, Piazza R, Rostagno R, et al. Activity of bosutinib, dasatinib, and nilotinib against 18 imatinib-resistant BCR/ABL mutants. J Clin Oncol 2009;27:469-471.
-
(2009)
J Clin Oncol
, vol.27
, pp. 469-471
-
-
Redaelli, S.1
Piazza, R.2
Rostagno, R.3
-
73
-
-
70349245253
-
Long-term outcome of patients with chronic myeloid leukemia treated with second-generation tyrosine kinase inhibitors after imatinib failure is predicted by the in vitro sensitivity of BCR-ABL kinase domain mutations
-
Jabbour E, Jones D, Kantarjian HM, et al. Long-term outcome of patients with chronic myeloid leukemia treated with second-generation tyrosine kinase inhibitors after imatinib failure is predicted by the in vitro sensitivity of BCR-ABL kinase domain mutations. Blood 2009;114:2037-2043.
-
(2009)
Blood
, vol.114
, pp. 2037-2043
-
-
Jabbour, E.1
Jones, D.2
Kantarjian, H.M.3
-
74
-
-
70350216731
-
Prevalence of T315I, dasatinib-specific resistant mutations (F317L, V299L, and T315A), and nilotinib-specific resistant mutations (P-loop and F359) at the time of imatinib resistance in chronic-phase chronic myeloid leukemia (CP-CML)
-
abstract Abstract 3236
-
Deininger MWN, Mauro MJ, Matloub Y, et al. Prevalence of T315I, dasatinib-specific resistant mutations (F317L, V299L, and T315A), and nilotinib-specific resistant mutations (P-loop and F359) at the time of imatinib resistance in chronic-phase chronic myeloid leukemia (CP-CML) [abstract]. Blood 2008;112:Abstract 3236.
-
(2008)
Blood
, vol.112
-
-
Deininger, M.W.N.1
Mauro, M.J.2
Matloub, Y.3
-
75
-
-
73949105873
-
Dasatinib treatment of chronic-phase chronic myeloid leukemia: Analysis of responses according to preexisting BCR-ABL mutations
-
Muller MC, Cortes JE, Kim DW, et al. Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. Blood 2009;114:4944-4953.
-
(2009)
Blood
, vol.114
, pp. 4944-4953
-
-
Muller, M.C.1
Cortes, J.E.2
Kim, D.W.3
-
76
-
-
58149380741
-
Characteristics and outcome of chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation after therapy with tyrosine kinase inhibitors
-
Jabbour E, Kantarjian HM, Jones D, et al. Characteristics and outcome of chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation after therapy with tyrosine kinase inhibitors. Blood 2008;112:4839-4842.
-
(2008)
Blood
, vol.112
, pp. 4839-4842
-
-
Jabbour, E.1
Kantarjian, H.M.2
Jones, D.3
-
77
-
-
34247644944
-
Resistance to dasatinib in Philadelphia-positive leukemia patients and the presence or the selection of mutations at residues 315 and 317 in the BCR-ABL kinase domain
-
DOI 10.3324/haematol.10822
-
Soverini S, Colarossi S, Gnani A, et al. Resistance to dasatinib in Philadelphia-positive leukemia patients and the presence or the selection of mutations at residues 315 and 317 in the BCR-ABL kinase domain. Haematologica 2007;92:401-404. (Pubitemid 350143551)
-
(2007)
Haematologica
, vol.92
, Issue.3
, pp. 401-404
-
-
Soverini, S.1
Colarossi, S.2
Gnani, A.3
Castagnetti, F.4
Rosti, G.5
Bosi, C.6
Paolini, S.7
Rondoni, M.8
Piccaluga, P.P.9
Palandri, F.10
Giannoulia, P.11
Marzocchi, G.12
Luatti, S.13
Testoni, N.14
Iacobucci, I.15
Cilloni, D.16
Saglio, G.17
Baccarani, M.18
Martinelli, G.19
-
78
-
-
70249105789
-
Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase
-
Hughes T, Saglio G, Branford S, et al. Impact of baseline BCR-ABL mutations on response to nilotinib in patients with chronic myeloid leukemia in chronic phase. J Clin Oncol 2009;27:4204-4210.
-
(2009)
J Clin Oncol
, vol.27
, pp. 4204-4210
-
-
Hughes, T.1
Saglio, G.2
Branford, S.3
-
79
-
-
33747154547
-
Evolving concepts in the management of chronic myeloid leukemia: Recommendations from an expert panel on behalf of the European LeukemiaNet
-
DOI 10.1182/blood-2006-02-005686
-
Baccarani M, Saglio G, Goldman J, et al. Evolving concepts in the management of chronic myeloid leukemia: recommendations from an expert panel on behalf of the European LeukemiaNet. Blood 2006;108:1809-1820. (Pubitemid 44394987)
-
(2006)
Blood
, vol.108
, Issue.6
, pp. 1809-1820
-
-
Baccarani, M.1
Saglio, G.2
Goldman, J.3
Hochhaus, A.4
Simonsson, B.5
Appelbaum, F.6
Apperley, J.7
Cervantes, F.8
Cortes, J.9
Deininger, M.10
Gratwohl, A.11
Guilhot, F.12
Horowitz, M.13
Hughes, T.14
Kantarjian, H.15
Larson, R.16
Niederwieser, D.17
Silver, R.18
Hehlmann, R.19
-
80
-
-
73349122639
-
Chronic myeloid leukemia: An update of concepts and management recommendations of European LeukemiaNet
-
Baccarani M, Cortes J, Pane F, et al. Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet. J Clin Oncol 2009;27:6041-6051.
-
(2009)
J Clin Oncol
, vol.27
, pp. 6041-6051
-
-
Baccarani, M.1
Cortes, J.2
Pane, F.3
-
81
-
-
67049087117
-
Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: The ADAGIO study
-
Noens L, van Lierde MA, De Bock R, et al. Prevalence, determinants, and outcomes of nonadherence to imatinib therapy in patients with chronic myeloid leukemia: the ADAGIO study. Blood 2009;113:5401-5411.
-
(2009)
Blood
, vol.113
, pp. 5401-5411
-
-
Noens, L.1
Van Lierde, M.A.2
De Bock, R.3
-
82
-
-
77952467377
-
Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib
-
Marin D, Bazeos A, Mahon FX, et al. Adherence is the critical factor for achieving molecular responses in patients with chronic myeloid leukemia who achieve complete cytogenetic responses on imatinib. J Clin Oncol 2010;28:2381-2388.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2381-2388
-
-
Marin, D.1
Bazeos, A.2
Mahon, F.X.3
-
83
-
-
34147174980
-
Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia
-
DOI 10.1182/blood-2006-07-036012
-
Picard S, Titier K, Etienne G, et al. Trough imatinib plasma levels are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia. Blood 2007;109:3496-3499. (Pubitemid 46572540)
-
(2007)
Blood
, vol.109
, Issue.8
, pp. 3496-3499
-
-
Picard, S.1
Titier, K.2
Etienne, G.3
Teilhet, E.4
Ducint, D.5
Bernard, M.-A.6
Lassalle, R.7
Marit, G.8
Reiffers, J.9
Begaud, B.10
Moore, N.11
Molimard, M.12
Mahon, F.-X.13
-
84
-
-
43249083718
-
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: A subanalysis of the IRIS study
-
Larson RA, Druker BJ, Guilhot F, et al. Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study. Blood 2008;111:4022-4028.
-
(2008)
Blood
, vol.111
, pp. 4022-4028
-
-
Larson, R.A.1
Druker, B.J.2
Guilhot, F.3
-
85
-
-
77949754010
-
Early dose-escalation in chronic myeloid leukaemia patients with low plasma imatinib levels leads to equivalent BCR-ABL values and drug levels at 6 months to those with optimal drug levels: First analysis from the TIDEL II trial of de-novo patients treated with 600mg imatinib
-
abstract Abstract 1131
-
Osborn MP, White DL, Saunders VA, et al. Early dose-escalation in chronic myeloid leukaemia patients with low plasma imatinib levels leads to equivalent BCR-ABL values and drug levels at 6 months to those with optimal drug levels: first analysis from the TIDEL II trial of de-novo patients treated with 600mg imatinib [abstract]. Blood 2009;114:Abstract 1131.
-
(2009)
Blood
, vol.114
-
-
Osborn, M.P.1
White, D.L.2
Saunders, V.A.3
-
86
-
-
38349193809
-
Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia
-
Wang L, Giannoudis A, Lane S, et al. Expression of the uptake drug transporter hOCT1 is an important clinical determinant of the response to imatinib in chronic myeloid leukemia. Clin Pharmacol Ther 2008;83:258-264.
-
(2008)
Clin Pharmacol Ther
, vol.83
, pp. 258-264
-
-
Wang, L.1
Giannoudis, A.2
Lane, S.3
-
87
-
-
37049028176
-
Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: Higher doses of imatinib may overcome the negative impact of low OCT-1 activity
-
White DL, Saunders VA, Dang P, et al. Most CML patients who have a suboptimal response to imatinib have low OCT-1 activity: higher doses of imatinib may overcome the negative impact of low OCT-1 activity. Blood 2007;110:4064-4072.
-
(2007)
Blood
, vol.110
, pp. 4064-4072
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
-
88
-
-
77954936879
-
Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib
-
White DL, Dang P, Engler J, et al. Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib. J Clin Oncol 2010;28:2761-2767.
-
(2010)
J Clin Oncol
, vol.28
, pp. 2761-2767
-
-
White, D.L.1
Dang, P.2
Engler, J.3
-
89
-
-
52449100460
-
Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: Therapeutic implications
-
Hiwase DK, Saunders V, Hewett D, et al. Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications. Clin Cancer Res 2008;14:3881-3888.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3881-3888
-
-
Hiwase, D.K.1
Saunders, V.2
Hewett, D.3
-
90
-
-
33745085275
-
OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): Reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib
-
White DL, Saunders VA, Dang P, et al. OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. Blood 2006;108:697-704.
-
(2006)
Blood
, vol.108
, pp. 697-704
-
-
White, D.L.1
Saunders, V.A.2
Dang, P.3
-
91
-
-
70450255111
-
Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters
-
Davies A, Jordanides NE, Giannoudis A, et al. Nilotinib concentration in cell lines and primary CD34(+) chronic myeloid leukemia cells is not mediated by active uptake or efflux by major drug transporters. Leukemia 2009;23:1999-2006.
-
(2009)
Leukemia
, vol.23
, pp. 1999-2006
-
-
Davies, A.1
Jordanides, N.E.2
Giannoudis, A.3
-
92
-
-
70350451078
-
The derivation of diagnostic markers of chronic myeloid leukemia progression from microarray data
-
Oehler VG, Yeung KY, Choi YE, et al. The derivation of diagnostic markers of chronic myeloid leukemia progression from microarray data. Blood 2009;114:3292-3298.
-
(2009)
Blood
, vol.114
, pp. 3292-3298
-
-
Oehler, V.G.1
Yeung, K.Y.2
Choi, Y.E.3
-
93
-
-
20844447330
-
Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations
-
DOI 10.1182/blood-2004-03-1134
-
Branford S, Rudzki Z, Parkinson I, et al. Real-time quantitative PCR analysis can be used as a primary screen to identify patients with CML treated with imatinib who have BCR-ABL kinase domain mutations. Blood 2004;104:2926-2932. (Pubitemid 39434981)
-
(2004)
Blood
, vol.104
, Issue.9
, pp. 2926-2932
-
-
Branford, S.1
Rudzki, Z.2
Parkinson, I.3
Grigg, A.4
Taylor, K.5
Seymour, J.F.6
Durrant, S.7
Browett, P.8
Schwarer, A.P.9
Arthur, C.10
Catalano, J.11
Leahy, M.F.12
Filshie, R.13
Bradstock, K.14
Herrmann, R.15
Joske, D.16
Lynch, K.17
Hughes, T.18
-
94
-
-
54349089682
-
Finding of kinase domain mutations in patients with chronic phase chronic myeloid leukemia responding to imatinib may identify those at high risk of disease progression
-
Khorashad JS, de Lavallade H, Apperley JF, et al. Finding of kinase domain mutations in patients with chronic phase chronic myeloid leukemia responding to imatinib may identify those at high risk of disease progression. J Clin Oncol 2008;26:4806-4813.
-
(2008)
J Clin Oncol
, vol.26
, pp. 4806-4813
-
-
Khorashad, J.S.1
De Lavallade, H.2
Apperley, J.F.3
-
95
-
-
33644516935
-
The role of serial BCR-ABL transcript monitoring in predicting the emergence of BCR-ABL kinase mutations in imatinib-treated patients with chronic myeloid leukemia
-
Wang L, Knight K, Lucas C, Clark R. The role of serial BCR-ABL transcript monitoring in predicting the emergence of BCR-ABL kinase mutations in imatinib-treated patients with chronic myeloid leukemia. Haematologica 2006;91:235-239.
-
(2006)
Haematologica
, vol.91
, pp. 235-239
-
-
Wang, L.1
Knight, K.2
Lucas, C.3
Clark, R.4
-
96
-
-
35948937212
-
A half-log increase in BCR-ABL RNA predicts a higher risk of relapse in patients with chronic myeloid leukemia with an imatinib-induced complete cytogenetic response
-
DOI 10.1158/1078-0432.CCR-07-1112
-
Press RD, Galderisi C, Yang R, et al. A half-log increase in BCRABL RNA predicts a higher risk of relapse in patients with chronic myeloid leukemia with an imatinib-induced complete cytogenetic response. Clin Cancer Res 2007;13:6136-6143. (Pubitemid 350075073)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.20
, pp. 6136-6143
-
-
Press, R.D.1
Galderisi, C.2
Yang, R.3
Rempfer, C.4
Willis, S.G.5
Mauro, M.J.6
Druker, B.J.7
Deininger, M.W.N.8
-
97
-
-
68549095201
-
Significance of rising levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) in complete cytogenetic response (CGCR)
-
abstract Abstract 445
-
Kantarjian HM, Shan J, Jones D, et al. Significance of rising levels of minimal residual disease in patients with Philadelphia chromosome-positive chronic myelogenous leukemia (Ph+ CML) in complete cytogenetic response (CGCR) [abstract]. Blood 2008;112:Abstract 445.
-
(2008)
Blood
, vol.112
-
-
Kantarjian, H.M.1
Shan, J.2
Jones, D.3
-
98
-
-
70350509806
-
Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib
-
Press RD, Willis SG, Laudadio J, et al. Determining the rise in BCR-ABL RNA that optimally predicts a kinase domain mutation in patients with chronic myeloid leukemia on imatinib. Blood 2009;114:2598-2605.
-
(2009)
Blood
, vol.114
, pp. 2598-2605
-
-
Press, R.D.1
Willis, S.G.2
Laudadio, J.3
-
99
-
-
0036566758
-
Adherence to therapy with oral antineoplastic agents
-
Partridge AH, Avorn J, Wang PS, Winer EP. Adherence to therapy with oral antineoplastic agents. J Natl Cancer Inst 2002;94:652-661. (Pubitemid 34552485)
-
(2002)
Journal of the National Cancer Institute
, vol.94
, Issue.9
, pp. 652-661
-
-
Partridge, A.H.1
Avorn, J.2
Wang, P.S.3
Winer, E.P.4
-
100
-
-
68549098145
-
Significance of suboptimal response to imatinib, as defined by the European LeukemiaNet, in the long-term outcome of patients with early chronic myeloid leukemia in chronic phase
-
Alvarado Y, Kantarjian H, O'Brien S, et al. Significance of suboptimal response to imatinib, as defined by the European LeukemiaNet, in the long-term outcome of patients with early chronic myeloid leukemia in chronic phase. Cancer 2009;115:3709-3718.
-
(2009)
Cancer
, vol.115
, pp. 3709-3718
-
-
Alvarado, Y.1
Kantarjian, H.2
O'Brien, S.3
-
101
-
-
79952782403
-
Chronic myeloid leukemia (CML) patients with "suboptimal" response to imatinib (IM) according to european leukemianet criteria have a poorer outcome with respect to "optimal" responders: A GIMEMA CML Working Party analysis
-
abstract Abstract 2196
-
Castagnetti F, Gugliotta G, Palandri F, et al. Chronic myeloid leukemia (CML) patients with "suboptimal" response to imatinib (IM) according to european leukemianet criteria have a poorer outcome with respect to "optimal" responders: a GIMEMA CML Working Party analysis [abstract]. Blood 2009;114:Abstract 2196.
-
(2009)
Blood
, vol.114
-
-
Castagnetti, F.1
Gugliotta, G.2
Palandri, F.3
-
102
-
-
58149396984
-
European Leukemia Net criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor
-
Marin D, Milojkovic D, Olavarria E, et al. European Leukemia Net criteria for failure or suboptimal response reliably identify patients with CML in early chronic phase treated with imatinib whose eventual outcome is poor. Blood 2008;112:4437-4444.
-
(2008)
Blood
, vol.112
, pp. 4437-4444
-
-
Marin, D.1
Milojkovic, D.2
Olavarria, E.3
-
103
-
-
77951557996
-
Imatinib dose escalation in 74 failure or suboptimal response chronic myeloid leukaemia patients at 3-year follow-up
-
Breccia M, Stagno F, Vigneri P, et al. Imatinib dose escalation in 74 failure or suboptimal response chronic myeloid leukaemia patients at 3-year follow-up. Am J Hematol 2010;85:375-377.
-
(2010)
Am J Hematol
, vol.85
, pp. 375-377
-
-
Breccia, M.1
Stagno, F.2
Vigneri, P.3
-
104
-
-
77953072695
-
Phase IV study evaluating efficacy of escalated dose of imatinib in chronic myeloid leukemia patients showing suboptimal response to standard dose imatinib
-
Koh Y, Kim I, Yoon SS, et al. Phase IV study evaluating efficacy of escalated dose of imatinib in chronic myeloid leukemia patients showing suboptimal response to standard dose imatinib. Ann Hematol 2010;89:725-731.
-
(2010)
Ann Hematol
, vol.89
, pp. 725-731
-
-
Koh, Y.1
Kim, I.2
Yoon, S.S.3
-
105
-
-
79952037284
-
Selective escalation of imatinib therapy and early switching to nilotinib in de novo chronic phase CML patients: Interim results from the TIDEL-II trial
-
abstract Abstract 209
-
Yeung DT, Osborn M, White DL, et al. Selective escalation of imatinib therapy and early switching to nilotinib in de novo chronic phase CML patients: interim results from the TIDEL-II trial [abstract]. Blood 2010;116:Abstract 209.
-
(2010)
Blood
, vol.116
-
-
Yeung, D.T.1
Osborn, M.2
White, D.L.3
-
106
-
-
71849094784
-
Dasatinib-associated major molecular responses are rapidly achieved in patients with chronic myeloid leukemia in chronic phase (CML-CP) following resistance, suboptimal response, or intolerance on imatinib
-
abstract Abstract 1095
-
Hochhaus A, Muller MC, Radich J, et al. Dasatinib-associated major molecular responses are rapidly achieved in patients with chronic myeloid leukemia in chronic phase (CML-CP) following resistance, suboptimal response, or intolerance on imatinib [abstract]. Blood 2008;112:Abstract 1095.
-
(2008)
Blood
, vol.112
-
-
Hochhaus, A.1
Muller, M.C.2
Radich, J.3
-
107
-
-
77955450607
-
Impact of prior therapy and suboptimal response to imatinib on the efficacy and safety of nilotinib among 1,422 patients with imatinib-resistant or -intolerant chronic myeloid leukemia (CML) in chronic phase (CP): Subanalyses of the ENACT (Expanding Nilotinib Access in Clinical Trials) study
-
abstract Abstract 2201
-
Nicolini FE, Kim DW, Ceglarek B, et al. Impact of prior therapy and suboptimal response to imatinib on the efficacy and safety of nilotinib among 1,422 patients with imatinib-resistant or -intolerant chronic myeloid leukemia (CML) in chronic phase (CP): subanalyses of the ENACT (Expanding Nilotinib Access In Clinical Trials) study [abstract]. Blood 2009;114:Abstract 2201.
-
(2009)
Blood
, vol.114
-
-
Nicolini, F.E.1
Kim, D.W.2
Ceglarek, B.3
-
108
-
-
78649662408
-
Nilotinib-associated molecular responses achieved in chronic myeloid leukemia in chronic phase (CML-CP) patients with a suboptimal molecular response to imatinib
-
abstract Abstract 2206
-
Yang AS, Jillella A, Miller CB, et al. Nilotinib-associated molecular responses achieved in chronic myeloid leukemia in chronic phase (CML-CP) patients with a suboptimal molecular response to imatinib [abstract]. Blood 2009;114:Abstract 2206.
-
(2009)
Blood
, vol.114
-
-
Yang, A.S.1
Jillella, A.2
Miller, C.B.3
-
109
-
-
37249016890
-
BCR-ABL messenger RNA levels continue to decline in patients with chronic phase chronic myeloid leukemia treated with imatinib for more than 5 years and approximately half of all first-line treated patients have stable undetectable BCR-ABL using strict sensitivity criteria
-
DOI 10.1158/1078-0432.CCR-07-0844
-
Branford S, Seymour JF, Grigg A, et al. BCR-ABL messenger RNA levels continue to decline in patients with chronic phase chronic myeloid leukemia treated with imatinib for more than 5 years and approximately half of all first-line treated patients have stable undetectable BCR-ABL using strict sensitivity criteria. Clin Cancer Res 2007;13:7080-7085. (Pubitemid 350276891)
-
(2007)
Clinical Cancer Research
, vol.13
, Issue.23
, pp. 7080-7085
-
-
Branford, S.1
Seymour, J.F.2
Grigg, A.3
Arthur, C.4
Rudzki, Z.5
Lynch, K.6
Hughes, T.7
-
110
-
-
4644341516
-
Discontinuation of imatinib therapy after achieving a molecular response [3]
-
DOI 10.1182/blood-2004-04-1335
-
Cortes J, O'Brien S, Kantarjian H. Discontinuation of imatinib therapy after achieving a molecular response. Blood 2004;104:2204-2205. (Pubitemid 39297882)
-
(2004)
Blood
, vol.104
, Issue.7
, pp. 2204-2205
-
-
Cortes, J.1
O'Brien, S.2
Kantarjian, H.3
-
111
-
-
67349120559
-
Is it possible to discontinue imatinib mesylate therapy in chronic myeloid leukemia patients with undetectable BCR/ABL? A case report and a review of the literature
-
Guastafierro S, Falcone U, Celentano M, et al. Is it possible to discontinue imatinib mesylate therapy in chronic myeloid leukemia patients with undetectable BCR/ABL? A case report and a review of the literature. Leuk Res 2009;33:1079-1081.
-
(2009)
Leuk Res
, vol.33
, pp. 1079-1081
-
-
Guastafierro, S.1
Falcone, U.2
Celentano, M.3
-
112
-
-
47649123285
-
Sustained complete molecular response after imatinib discontinuation in a patient with chronic myeloid leukemia not previously exposed to interferon alpha
-
DOI 10.1080/10428190802043903, PII 791910910
-
Verma D, Kantarjian H, Jain N, Cortes J. Sustained complete molecular response after imatinib discontinuation in a patient with chronic myeloid leukemia not previously exposed to interferon alpha. Leuk Lymphoma 2008;49:1399-1402. (Pubitemid 352015805)
-
(2008)
Leukemia and Lymphoma
, vol.49
, Issue.7
, pp. 1399-1402
-
-
Verma, D.1
Kantarjian, H.2
Jain, N.3
Cortes, J.4
-
113
-
-
78049528573
-
Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: The prospective, multicentre Stop Imatinib (STIM) trial
-
Mahon FX, Rea D, Guilhot J, et al. Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective, multicentre Stop Imatinib (STIM) trial. Lancet Oncol 2010:1029-1035.
-
(2010)
Lancet Oncol
, pp. 1029-1035
-
-
Mahon, F.X.1
Rea, D.2
Guilhot, J.3
-
114
-
-
77949512757
-
The majority of chronic myeloid leukaemia patients who cease imatinib after achieving a sustained complete molecular response (CMR) remain in cmr, and any relapses occur early
-
abstract Abstract 1102
-
Ross DDM, Grigg A, Schwarer A, et al. The majority of chronic myeloid leukaemia patients who cease imatinib after achieving a sustained complete molecular response (CMR) remain in cmr, and any relapses occur early [abstract]. Blood 2008;112:Abstract 1102.
-
(2008)
Blood
, vol.112
-
-
Ross, D.D.M.1
Grigg, A.2
Schwarer, A.3
-
115
-
-
0035313619
-
Equivalent outcomes in patients with chronic myelogenous leukemia after early transplantation of phenotypically matched bone marrow from related or unrelated donors
-
DOI 10.1016/S0002-9343(01)00629-5, PII S0002934301006295
-
Davies SM, DeFor TE, McGlave PB, et al. Equivalent outcomes in patients with chronic myelogenous leukemia after early transplantation of phenotypically matched bone marrow from related or unrelated donors. Am J Med 2001;110:339-346. (Pubitemid 32245805)
-
(2001)
American Journal of Medicine
, vol.110
, Issue.5
, pp. 339-346
-
-
Davies, S.M.1
DeFor, T.E.2
McGlave, P.B.3
Miller, J.S.4
Verfaillie, C.M.5
Wagner, J.E.6
Weisdorf, D.J.7
-
116
-
-
0008947293
-
Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia
-
DOI 10.1056/NEJM199804023381405
-
Hansen JA, Gooley TA, Martin PJ, et al. Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia. N Engl J Med 1998;338:962-968. (Pubitemid 28152837)
-
(1998)
New England Journal of Medicine
, vol.338
, Issue.14
, pp. 962-968
-
-
Hansen, J.A.1
Gooley, T.A.2
Martin, P.J.3
Appelbaum, F.4
Chauncey, T.R.5
Clift, R.A.6
Petersdorf, E.W.7
Radich, J.8
Sanders, J.E.9
Storb, R.F.10
Sullivan, K.M.11
Anasetti, C.12
-
117
-
-
79951675978
-
Long-term outcomes of HLA-matched sibling compared with mismatched related and unrelated donor hematopoietic stem cell transplantation for chronic phase chronic myelogenous leukemia: A single institution experience in China
-
in press
-
Liu QF, Xu XJ, Chen YK, et al. Long-term outcomes of HLA-matched sibling compared with mismatched related and unrelated donor hematopoietic stem cell transplantation for chronic phase chronic myelogenous leukemia: a single institution experience in China. Ann Hematol 2010; in press..
-
(2010)
Ann Hematol
-
-
Liu, Q.F.1
Xu, X.J.2
Chen, Y.K.3
-
118
-
-
74049104918
-
Nonmyeloablative allogeneic stem cell transplantation for chronic myelogenous leukemia in the imatinib era
-
Champlin R, de Lima M, Kebriaei P, et al. Nonmyeloablative allogeneic stem cell transplantation for chronic myelogenous leukemia in the imatinib era. Clin Lymphoma Myeloma 2009;9:S261-265.
-
(2009)
Clin Lymphoma Myeloma
, vol.9
-
-
Champlin, R.1
De Lima, M.2
Kebriaei, P.3
-
119
-
-
27644550034
-
Outcomes of reduced-intensity transplantation for chronic myeloid leukemia: An analysis of prognostic factors from the Chronic Leukemia Working Party of the EBMT
-
DOI 10.1182/blood-2004-09-3544
-
Crawley C, Szydlo R, Lalancette M, et al. Outcomes of reduced-intensity transplantation for chronic myeloid leukemia: an analysis of prognostic factors from the Chronic Leukemia Working Party of the EBMT. Blood 2005;106:2969-2976. (Pubitemid 41565887)
-
(2005)
Blood
, vol.106
, Issue.9
, pp. 2969-2976
-
-
Crawley, C.1
Szydlo, R.2
Lalancette, M.3
Bacigalupo, A.4
Lange, A.5
Brune, M.6
Juliusson, G.7
Nagler, A.8
Gratwohl, A.9
Passweg, J.10
Komarnicki, M.11
Vitek, A.12
Mayer, J.13
Zander, A.14
Sierra, J.15
Rambaldi, A.16
Ringden, O.17
Niederwieser, D.18
Apperley, J.F.19
-
120
-
-
0037438397
-
Nonmyeloablative allogeneic stem cell transplantation for the treatment of chronic myeloid leukemia in first chronic phase
-
DOI 10.1182/blood-2002-02-0535
-
Or R, Shapira MY, Resnick I, et al. Nonmyeloablative allogeneic stem cell transplantation for the treatment of chronic myeloid leukemia in first chronic phase. Blood 2003;101:441-445. (Pubitemid 36077561)
-
(2003)
Blood
, vol.101
, Issue.2
, pp. 441-445
-
-
Or, R.1
Shapira, M.Y.2
Resnick, I.3
Amar, A.4
Ackerstein, A.5
Samuel, S.6
Aker, M.7
Naparstek, E.8
Nagler, A.9
Slavin, S.10
-
121
-
-
34247248807
-
Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure
-
DOI 10.1002/cncr.22569
-
Kantarjian H, O'Brien S, Talpaz M, et al. Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure. Cancer 2007;109:1556-1560. (Pubitemid 46603580)
-
(2007)
Cancer
, vol.109
, Issue.8
, pp. 1556-1560
-
-
Kantarjian, H.1
O'Brien, S.2
Talpaz, M.3
Borthakur, G.4
Ravandi, F.5
Faderl, S.6
Verstovsek, S.7
Rios, M.B.8
Shan, J.9
Giles, F.10
Cortes, J.11
-
122
-
-
77957088676
-
Stem cell transplant for chronic myeloid leukemia in the imatinib era
-
Radich J. Stem cell transplant for chronic myeloid leukemia in the imatinib era. Semin Hematol 2010;47:354-361.
-
(2010)
Semin Hematol
, vol.47
, pp. 354-361
-
-
Radich, J.1
-
123
-
-
0032480589
-
Risk assessment for patients with chronic myeloid leukaemia before allogeneic blood or marrow transplantation
-
DOI 10.1016/S0140-6736(98)03030-X
-
Gratwohl A, Hermans J, Goldman JM, et al. Risk assessment for patients with chronic myeloid leukaemia before allogeneic blood or marrow transplantation. Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation. Lancet 1998;352:1087-1092. (Pubitemid 28448513)
-
(1998)
Lancet
, vol.352
, Issue.9134
, pp. 1087-1092
-
-
Gratwohl, A.1
Hermans, J.2
Goldman, J.M.3
Arcese, W.4
Carreras, E.5
Devergie, A.6
Frassoni, F.7
Gahrton, G.8
Kolb, H.J.9
Niederwieser, D.10
Ruutu, T.11
Vernant, J.P.12
De Witte, T.13
Apperley, J.14
-
124
-
-
77953261487
-
Optimizing patient selection for myeloablative allogeneic hematopoietic cell transplantation in chronic myeloid leukemia in chronic phase
-
Pavlu J, Kew AK, Taylor-Roberts B, et al. Optimizing patient selection
-
(2010)
Blood
, vol.115
, pp. 4018-4020
-
-
Pavlu, J.1
Kew, A.K.2
Taylor-Roberts, B.3
-
125
-
-
0029952614
-
Allogeneic bone marrow transplantation for CML: A report from the International Bone Marrow Transplant Registry
-
Horowitz MM, Rowlings PA, Passweg JR. Allogeneic bone marrow transplantation for CML: a report from the International Bone Marrow Transplant Registry. Bone Marrow Transplant 1996;17(Suppl 3):S5-6.
-
(1996)
Bone Marrow Transplant
, vol.17
, Issue.SUPPL. 3
-
-
Horowitz, M.M.1
Rowlings, P.A.2
Passweg, J.R.3
-
127
-
-
79952799331
-
Improved outcome in patients with chronic myeloid leukemia after allogeneic hematopoietic stem cell transplantation over the past 25 years: A single center experience
-
Boehm A, Walcherberger B, Sperr WR, et al. Improved outcome in patients with chronic myeloid leukemia after allogeneic hematopoietic stem cell transplantation over the past 25 years: a single center experience. Biol Blood Marrow Transplant 2011;17;133-140.
-
(2011)
Biol Blood Marrow Transplant
, vol.17
, pp. 133-140
-
-
Boehm, A.1
Walcherberger, B.2
Sperr, W.R.3
-
128
-
-
33646017748
-
Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia in Europe 2006: Transplant activity, long-term data and current results. An analysis by the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)
-
Gratwohl A, Brand R, Apperley J, et al. Allogeneic hematopoietic stem cell transplantation for chronic myeloid leukemia in Europe 2006: transplant activity, long-term data and current results. An analysis by the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT). Haematologica 2006;91:513-521.
-
(2006)
Haematologica
, vol.91
, pp. 513-521
-
-
Gratwohl, A.1
Brand, R.2
Apperley, J.3
-
129
-
-
77950391550
-
Allogeneic hematopoietic stem cell transplantation (allo SCT) for chronic myeloid leukemia in the imatinib era: Evaluation of its impact within a subgroup of the randomized German CML Study IV
-
Saussele S, Lauseker M, Gratwohl A, et al. Allogeneic hematopoietic stem cell transplantation (allo SCT) for chronic myeloid leukemia in the imatinib era: evaluation of its impact within a subgroup of the randomized German CML Study IV. Blood 2010;115:1880-1885.
-
(2010)
Blood
, vol.115
, pp. 1880-1885
-
-
Saussele, S.1
Lauseker, M.2
Gratwohl, A.3
-
130
-
-
77951632041
-
Relapse and late mortality in 5-year survivors of myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase
-
Goldman JM, Majhail NS, Klein JP, et al. Relapse and late mortality in 5-year survivors of myeloablative allogeneic hematopoietic cell transplantation for chronic myeloid leukemia in first chronic phase. J Clin Oncol 2010;28:1888-1895.
-
(2010)
J Clin Oncol
, vol.28
, pp. 1888-1895
-
-
Goldman, J.M.1
Majhail, N.S.2
Klein, J.P.3
-
131
-
-
0028988779
-
Prolonged administration of interferon-alpha in patients with chronic-phase Philadelphia chromosome-positive chronic myelogenous leukemia before allogeneic bone marrow transplantation may adversely affect transplant outcome
-
Beelen DW, Graeven U, Elmaagacli AH, et al. Prolonged administration of interferon-alpha in patients with chronic-phase Philadelphia chromosome-positive chronic myelogenous leukemia before allogeneic bone marrow transplantation may adversely affect transplant outcome. Blood 1995;85:2981-2990.
-
(1995)
Blood
, vol.85
, pp. 2981-2990
-
-
Beelen, D.W.1
Graeven, U.2
Elmaagacli, A.H.3
-
132
-
-
0027504040
-
Choice of pretransplant treatment and timing of transplants for chronic myelogenous leukemia in chronic phase
-
Goldman JM, Szydlo R, Horowitz MM, et al. Choice of pretrans-plant treatment and timing of transplants for chronic myelogenous leukemia in chronic phase. Blood 1993;82:2235-2238. (Pubitemid 23294011)
-
(1993)
Blood
, vol.82
, Issue.7
, pp. 2235-2238
-
-
Goldman, J.M.1
Szydlo, R.2
Horowitz, M.M.3
Gale, R.P.4
Ash, R.C.5
Atkinson, K.6
Dicke, K.A.7
Gluckman, E.8
Herzig, R.H.9
Marmont, A.10
Masaoka, T.11
McGlave, P.B.12
Messner, H.13
O'Reilly, R.J.14
Reiffers, J.15
Rimm, A.A.16
Speck, B.17
Veum-Stone, J.A.18
Wingard, J.R.19
-
133
-
-
2642643774
-
Association between pretransplant interferon-alpha and outcome after unrelated donor marrow transplantation for chronic myelogenous leukemia in chronic phase
-
Morton AJ, Gooley T, Hansen JA, et al. Association between pretransplant interferon-alpha and outcome after unrelated donor marrow transplantation for chronic myelogenous leukemia in chronic phase. Blood 1998;92:394-401. (Pubitemid 28323699)
-
(1998)
Blood
, vol.92
, Issue.2
, pp. 394-401
-
-
James, M.A.1
Gooley, T.2
Hansen, J.A.3
Appelbaum, F.R.4
Bruemmer, B.5
Bjerke, J.W.6
Clift, R.7
Martin, P.J.8
Petersdorf, E.W.9
Sanders, J.E.10
Storb, R.11
Sullivan, K.M.12
Woolfrey, A.13
Anasetti, C.14
-
134
-
-
10344241010
-
Re: Imatinib mesylate administration in the first 100 days after stem cell transplantation
-
DOI 10.1016/j.bbmt.2004.09.004, PII S1083879104004872
-
Anderlini P, Sheth S, Hicks K, et al. Re: imatinib mesylate administration in the first 100 days after stem cell transplantation. Biol Blood Marrow Transplant 2004;10:883-884. (Pubitemid 39625310)
-
(2004)
Biology of Blood and Marrow Transplantation
, vol.10
, Issue.12
, pp. 883-884
-
-
Anderlini, P.1
Sheth, S.2
Hicks, K.3
Ippoliti, C.4
Giralt, S.5
Champlin, R.E.6
-
135
-
-
33646013280
-
The effect of prior exposure to imatinib on transplant-related mortality
-
Deininger M, Schleuning M, Greinix H, et al. The effect of prior exposure to imatinib on transplant-related mortality. Haematologica 2006;91:452-459.
-
(2006)
Haematologica
, vol.91
, pp. 452-459
-
-
Deininger, M.1
Schleuning, M.2
Greinix, H.3
-
136
-
-
54049146732
-
Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia
-
Lee SJ, Kukreja M, Wang T, et al. Impact of prior imatinib mesylate on the outcome of hematopoietic cell transplantation for chronic myeloid leukemia. Blood 2008;112:3500-3507.
-
(2008)
Blood
, vol.112
, pp. 3500-3507
-
-
Lee, S.J.1
Kukreja, M.2
Wang, T.3
-
137
-
-
33846925617
-
The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia
-
DOI 10.1182/blood-2006-06-031682
-
Oehler VG, Gooley T, Snyder DS, et al. The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia. Blood 2007;109:1782-1789. (Pubitemid 46239615)
-
(2007)
Blood
, vol.109
, Issue.4
, pp. 1782-1789
-
-
Oehler, V.G.1
Gooley, T.2
Snyder, D.S.3
Johnston, L.4
Lin, A.5
Cummings, C.C.6
Chu, S.7
Bhatia, R.8
Forman, S.J.9
Negrin, R.S.10
Appelbaum, F.R.11
Radich, J.P.12
-
138
-
-
84863399997
-
Allogeneic stem cell transplantation for blast crisis (BC) chronic myelogenous leukemia (CML) in the tyrosine kinase inhibitors (TKIs) era. Analysis of pre-transplant variables on transplant outcome. On behalf of the Societe Francaise de Greffe de Moelle et de Therapie Cellulaire and the French Group of CML
-
abstract Abstract 2266
-
Nicolini F, Modolo L, Raus N, et al. Allogeneic stem cell transplantation for blast crisis (BC) chronic myelogenous leukemia (CML) in the tyrosine kinase inhibitors (TKIs) era. Analysis of pre-transplant variables on transplant outcome. On behalf of the Societe Francaise De Greffe De Moelle Et De Therapie Cellulaire and the French Group of CML [abstract]. Blood 2010;116:Abstract 2266.
-
(2010)
Blood
, vol.116
-
-
Nicolini, F.1
Modolo, L.2
Raus, N.3
-
139
-
-
74849117346
-
Second-generation tyrosine kinase inhibitors before allogeneic stem cell transplantation in patients with chronic myeloid leukemia resistant to imatinib
-
Breccia M, Palandri F, Iori AP, et al. Second-generation tyrosine kinase inhibitors before allogeneic stem cell transplantation in patients with chronic myeloid leukemia resistant to imatinib. Leuk Res 2010;34:143-147.
-
(2010)
Leuk Res
, vol.34
, pp. 143-147
-
-
Breccia, M.1
Palandri, F.2
Iori, A.P.3
-
140
-
-
34547178987
-
Novel tyrosine kinase inhibitor therapy before allogeneic stem cell transplantation in patients with chronic myeloid leukemia: No evidence for increased transplant-related toxicity
-
DOI 10.1002/cncr.22778
-
Jabbour E, Cortes J, Kantarjian H, et al. Novel tyrosine kinase inhibitor therapy before allogeneic stem cell transplantation in patients with chronic myeloid leukemia: no evidence for increased transplant-related toxicity. Cancer 2007;110:340-344. (Pubitemid 47121894)
-
(2007)
Cancer
, vol.110
, Issue.2
, pp. 340-344
-
-
Jabbour, E.1
Cortes, J.2
Kantarjian, H.3
Giralt, S.4
Andersson, B.S.5
Giles, F.6
Shpall, E.7
Kebriaei, P.8
Champlin, R.9
De Lima, M.10
-
141
-
-
58249104311
-
Prior treatment with the tyrosine kinase inhibitors dasatinib and nilotinib allows stem cell transplantation (SCT) in a less advanced disease phase and does not increase SCT toxicity in patients with chronic myelogenous leukemia and philadelphia positive acute lymphoblastic leukemia
-
Shimoni A, Leiba M, Schleuning M, et al. Prior treatment with the tyrosine kinase inhibitors dasatinib and nilotinib allows stem cell transplantation (SCT) in a less advanced disease phase and does not increase SCT toxicity in patients with chronic myelogenous leukemia and philadelphia positive acute lymphoblastic leukemia. Leukemia 2009;23:190-194.
-
(2009)
Leukemia
, vol.23
, pp. 190-194
-
-
Shimoni, A.1
Leiba, M.2
Schleuning, M.3
-
142
-
-
34249664406
-
Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia
-
DOI 10.1182/blood-2006-11-055186
-
Hehlmann R, Berger U, Pfirrmann M, et al. Drug treatment is superior to allografting as first-line therapy in chronic myeloid leukemia. Blood 2007;109:4686-4692. (Pubitemid 46827759)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 4686-4692
-
-
Hehlmann, R.1
Berger, U.2
Pfirrmann, M.3
Heimpel, H.4
Hochhaus, A.5
Hasford, J.6
Kolb, H.-J.7
Lahaye, T.8
Maywald, O.9
Reiter, A.10
Hossfeld, D.K.11
Huber, C.12
Loffler, H.13
Pralle, H.14
Queisser, W.15
Tobler, A.16
Nerl, C.17
Solenthaler, M.18
Goebeler, M.E.19
Griesshammer, M.20
Fischer, T.21
Kremers, S.22
Eimermacher, H.23
Pfreundschuh, M.24
Hirschmann, W.-D.25
Lechner, K.26
Wassmann, B.27
Falge, C.28
Kirchner, H.H.29
Gratwohl, A.30
more..
-
143
-
-
77955368678
-
Stem cell transplantation for patients with chronic myeloid leukemia resistant to tyrosine kinase inhibitors with BCR-ABL kinase domain mutation T315I
-
Velev N, Cortes J, Champlin R, et al. Stem cell transplantation for patients with chronic myeloid leukemia resistant to tyrosine kinase inhibitors with BCR-ABL kinase domain mutation T315I. Cancer 2010;116:3631-3637.
-
(2010)
Cancer
, vol.116
, pp. 3631-3637
-
-
Velev, N.1
Cortes, J.2
Champlin, R.3
-
144
-
-
50949119729
-
Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia
-
Tam CS, Kantarjian H, Garcia-Manero G, et al. Failure to achieve a major cytogenetic response by 12 months defines inadequate response in patients receiving nilotinib or dasatinib as second or subsequent line therapy for chronic myeloid leukemia. Blood 2008;112:516-518.
-
(2008)
Blood
, vol.112
, pp. 516-518
-
-
Tam, C.S.1
Kantarjian, H.2
Garcia-Manero, G.3
-
145
-
-
76549114789
-
Early prediction of success or failure of treatment with second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia
-
Milojkovic D, Nicholson E, Apperley JF, et al. Early prediction of success or failure of treatment with second-generation tyrosine kinase inhibitors in patients with chronic myeloid leukemia. Haematologica 2010;95:224-231.
-
(2010)
Haematologica
, vol.95
, pp. 224-231
-
-
Milojkovic, D.1
Nicholson, E.2
Apperley, J.F.3
-
146
-
-
0021336851
-
Prognostic discrimination in "good-risk" chronic granulocytic leukemia
-
Sokal J, Cox E, Baccarani M, et al. Prognostic discrimination in "good-risk" chronic granulocytic leukemia. Blood 1984;63:789-799.
-
(1984)
Blood
, vol.63
, pp. 789-799
-
-
Sokal, J.1
Cox, E.2
Baccarani, M.3
-
147
-
-
0032478962
-
A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa
-
Hasford J, Pfirrmann M, Hehlmann R, et al. A new prognostic score for survival of patients with chronic myeloid leukemia treated with interferon alfa. Writing Committee for the Collaborative CML Prognostic Factors Project Group. J Natl Cancer Inst 1998;90:850-858. (Pubitemid 28280552)
-
(1998)
Journal of the National Cancer Institute
, vol.90
, Issue.11
, pp. 850-858
-
-
Hasford, J.1
Pfirrmann, M.2
Hehlmann, R.3
Allan, N.C.4
Baccarani, M.5
Kluin-Nelemans, J.C.6
Alimena, G.7
Steegmann, J.L.8
Ansari, H.9
|