The relationship between periodontal disease (Pd) and cardiovascular disease (Cvd)

Mediterranean Journal of Hematology and Infectious Diseases

Volumn 2, Issue 3, 2010, Pages

  Trevisan, Maurizio ^a   Dorn, Joan ^b  

^a Nevada System of Higher Education   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; CHOLESTEROL;

ATHEROSCLEROSIS; BLOOD PRESSURE; CARDIOVASCULAR DISEASE; CAUSAL ATTRIBUTION; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; CORONARY ARTERY DISEASE; DISEASE ASSOCIATION; EXPOSURE; GINGIVITIS; GLUCOSE METABOLISM; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; HUMAN; IMMUNE RESPONSE; NON INVASIVE MEASUREMENT; OSTEOLYSIS; PATHOGENESIS; PERIODONTAL DISEASE; PROGNOSIS; PUBLIC HEALTH; REVIEW; SMOKING;

EID: 79952789279     PISSN: None     EISSN: 20353006     Source Type: Journal    
DOI: 10.4084/MJHID.2010.030     Document Type: Review

References (44)

1. Haraszthy VI, Zambon JJ, Trevisan M, Zeid M, Genco RJ. Identification of periodontal pathogens in atheromatous plaques. J Periodontol 2000; 71:1554-1560.
2. Nakano K, Inaba H, Nomura R, Nemoto H, Takeda M, Yoshioka H et al. Detection of cariogenic Streptococcus mutans in extirpated heart valve and atheromatous plaque specimens. J Clin Microbiol 2006; 44:3313-3317.
3. Fiehn NE, Larsen T, Christiansen N, Holmstrup P, Schroeder TV. Identification of periodontal pathogens in atherosclerotic vessels. Journal of Periodontology2005; 76:731-6.
4. Aimetti M, Romano F, Nessi F. Microbiologic analysis of periodontal pockets and carotid atheromatous plaques in advanced chronic periodontitis patients. J Periodontol 2007; 78:1718-1723.
5. Cairo F, Gaeta C, Dorigo W, Oggioni MR, Pratesi C, Pini Prato GP et al. Periodontal pathogens in atheromatous plaques. A controlled clinical and laboratory trial. J Periodontal Res 2004;39:442-446.
6. Elkaim R, Dahan M, Kocgozlu L, Werner S, Kanter D, Kretz JG et al. Prevalence of periodontal pathogens in subgingival lesions, atherosclerotic plaques and healthy blood vessels: a preliminary study. J Periodontal Res 2008; 43:224-231.
7. Wu, T. Trevisan, M. Genco, R J. Falkner, K L. Dorn, J P. Sempos, C T. Examination of the relation between periodontal health status and cardiovascular risk factors: serum total and high density lipoprotein cholesterol, Creactive protein, and plasma fibrinogen. Am J Epidemiol. 151:273-82, 2000
8. Katz J, Flugelman MY, Goldberg A, Heft M. Association between periodontal pockets and elevated cholesterol and low density lipoprotein cholesterol levels. J Periodontol 2002;73:494-500.
9. Joshipura, K J. Wand, H C. Merchant, A T. Rimm, E B. Periodontal disease and biomarkers related to cardiovascular disease. J Dent Res. 2004; 83:151-5.
10. Grossi SG. Genco RJ. Periodontal disease and diabetes mellitus: a two way relationship. Annals of Periodontology. 1988; 3:51-61.
11. Losche W, Karapetow F, Pohl A, Pohl C, Kocher T. Plasma lipid and blood glucose levels in patients with destructive periodontal disease. J Clin Periodontol 2000; 27:537-541
12. Taguchi A. Sanada M. Suei Y. Ohtsuka M. Lee K. Tanimoto K. Tsuda M. Ohama K. Yoshizumi M. Higashi Y. Tooth loss is associated with an increased risk of hypertension in post-menopausal women. Hypertension 2004; 43:1297-300.
13. D'Aiuto, F., Parkar, M., Nibali, L., Suvan, J., Lessem, J. & Tonetti, M. S. Periodontal infections cause changes in traditional and novel cardiovascular risk factors: results from a randomized controlled clinical trial. American Heart Journal 2006; 151: 977-984.
14. Sharma A, Novak EK, Sojar HT, Swank RT, Kuramitsu HK, Genco RJ. Porphyromonas gingivalis platelet aggregation activity: outer membrane vesicles are potent activators of murine platelets. Oral Microbiol Immunol. 2000;15:393-6
15. P D'Aiuto F, Parkar M, Andreou G, Suvan J, Brett PM, Ready D et al. Periodontitis and systemic inflammation: control of the local infection is associated with a reduction in serum inflammatory markers. J Dent Res 2004; 83:156-160.
16. Seymour GJ, Ford PJ, Cullinan MP, Leishman S, Yamazaki K. Relationship between periodontal infections and systemic disease. Clin Microbiol Infect 2007; 13 Suppl 4:3-10.
17. Andriankaja OM, Genco RJ, Dorn J, Dmochowski J, Hovey K, Falkner KL et al. Periodontal disease and risk of myocardial infarction: the role of gender and smoking. Eur J Epidemiol 2007; 22:699-705
18. Mattila KJ, Nieminen MS, Valtonen VV, Rasi VP, Kesäniemi YA, Syrjälä SL et al. Association between dental health and acute myocardial infarction. Br Med J 1989; 298:779-781.
19. P DeStefano F, Anda RF, Kahn HS, Williamson DF, Russell CM. Dental disease and risk of coronary heart disease and mortality. BMJ 1993; 306:688-691.
20. Howell TH, Ridker PM, Ajani UA, Hennekens CH, Christen WG. Periodontal disease and risk of subsequent cardiovascular disease in U.S. male physicians. J Am Coll Cardiol. 2001;37:445-50.
21. Persson RG, Ohlsson O, Pettersson T, Renvert S. Chronic periodontitis, a significant relationship with acute myocardial infarction. Eur Heart J. 2003;24:2108-15.
22. Dorn JM. Genco RJ. Grossi SG. Falkner KL. Hovey KM. Iacoviello L. Trevisan M. Periodontal disease and recurrent cardiovascular events in survivors of myocardial infarction (MI): the Western New York Acute MI Study. 2010; J Periodontol. 81:502-11.
23. Humphrey LL, Fu R, Buckley DI, Freeman M, Helfand M. Periodontal disease and coronary heart disease incidence: a systematic review and meta-analysis. J Gen Intern Med 2008; 23:2079-2086.
24. Blaizot A, Vergnes JN, Nuwwareh S, Amar J, Sixou M. Periodontal diseases and cardiovascular events: metaanalysis of observational studies.International Dental Journa 2009; 59:197-209.
25. Syrjanen J, Peltola J, Valtonen V, et al. Dental infections in association with cerebral infarction in young and middleages men. J Intern Med. 1989;225:179-84.
26. Wu T, Trevisan M, Genco RJ, Dorn JP, Falkner KL, Sempos CT. Periodontal disease and risk of cerebrovascular disease: the first national health and nutrition examination survey and its follow-up study. Arch Intern Med 2000; 160:2749-2755.
27. Pussinen PJ, Alfthan G, Rissanen H, Reunanen A, Asikainen S, Knekt P. Antibodies to periodontal pathogens and stroke risk. Stroke 2004; 35:2020-2023.
28. Choe H, Kim YH, Park JW, Kim SY, Lee SY, Jee SH. Tooth loss, hypertension and risk for stroke in a Korean population. Atherosclerosis 2009; 203:550-556.
29. Beck JD, Elter JR, Heiss G, Couper D, Mauriello SM, Offenbacher S. Relationship of periodontal disease to carotid artery intima-media wall thickness: the Atherosclerosis Risk in Communities (ARIC) study. Arterioscler Thromb Vasc Biol. 2001;21:1816-22.
30. Desvarieux M, Demmer RT, Rundek T, et al. Relationship between periodontal disease, tooth loss, and carotid artery plaque: the Oral Infections and Vascular Disease Epidemiology Study (INVEST). Stroke. 2003;34:2120-5.
31. Nakib SA, Pankow JS, Beck JD, et al. Periodontitis and coronary artery calcification: the Atherosclerosis Risk in Communities (ARIC) study. J Periodontol. 2004;75:505-10.
32. Amar S, Gokce N, Morgan S, Loukideli M, Van Dyke TE, Vita JA. Periodontal disease is associated with brachial artery endothelial dysfunction and systemic inflammation. Arterioscler Thromb Vasc Biol 2003; 23:1245-1249.
33. Higashi Y, Goto C, Jitsuiki D, Umemura T, Nishioka K, Hidaka T et al. Periodontal infection is associated with endothelial dysfunction in healthy subjects and hypertensive patients. Hypertension 2008; 51:446-453.
34. Mercanoglu F, Oflaz H, Oz O, Gokbuget AY, Genchellac H, Sezer M et al. Endothelial dysfunction in patients with chronic periodontitis and its improvement after initial periodontal therapy. J Periodontol 2004; 75:1694-1700.
35. Hujoel PP, Drangsholt M, Spiekerman C, DeRouen TA. Periodontal disease and coronary heart disease risk. JAMA. 2000;284:1406-10.
36. Saremi A. Nelson RG. Tulloch-Reid M. Hanson RL. Sievers ML. Taylor GW. Shlossman M. Bennett PH. Genco R. Knowler WC. Periodontal disease and mortality in type 2 diabetes. Diabetes Care. 2005; 28:27-32.
37. Beck, J. D., Eke, P., Lin, D., Madianos, P., Couper, D., Moss, K., Elter, J., Heiss, G. & Offenbacher, S. Associations between IgG antibody to oral organisms and carotid intimamedial thickness in community-dwelling adults. Atherosclerosis. 2005; 183, 342-348.
38. Yamazaki K, Honda T, Oda T, Ueki-Maruyama K, Nakajima T, Yoshie H et al. Effect of periodontal treatment on the C-reactive protein and proinflammatory cytokine levels in Japanese periodontitis patients. J Periodontal Res 2005; 40:53-58.
39. D'Aiuto F, Parkar M, Andreou G, Suvan J, Brett PM, Ready D et al. Periodontitis and systemic inflammation: control of the local infection is associated with a reduction in serum inflammatory markers. J Dent Res 2004; 83:156-160.
40. Behle JH, Sedaghatfar MH, Demmer RT, Wolf DL, Celenti R, Kebschull M et al. Heterogeneity of systemic inflammatory responses to periodontal therapy. J Clin Periodontol 2009; 36:287-294.
41. Offenbacher S, Beck JD, Moss K, Mendoza L, Paquette DW, Barrow DA et al. Results from the Periodontitis and Vascular Events (PAVE) Study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease. J Periodontol 2009; 80(2):190-201.
42. Seinost G, Wimmer G, Skerget M, Thaller E, Brodmann M, Gasser R et al. Periodontal treatment improves endothelial dysfunction in patients with severe periodontitis. Am Heart J 2005; 149:1050-1054.
43. Tonetti MS, D'Aiuto F, Nibali L, Donald A, Storry C, Parkar M et al. Treatment of periodontitis and endothelial function. N Engl J Med 2007; 356:911-920.
44. Piconi S, Trabattoni D, Luraghi C, Perilli E, Borelli M, Pacei M, Rizzardini G, Lattuad A, Bray D H, Catalano M, Sparaco A, Clerici M. Treatment of periodontal disease results in improvements in endothelial dysfunction and reduction of the carotid intima-media thickness. The FASEB Journal 2009;23, 1196-1204.