Pyrimidine salvage pathway in Mycobacterium tuberculosis

Current Medicinal Chemistry

Volumn 18, Issue 9, 2011, Pages 1286-1298

  Villela, A D ^a   Sanchez Quitian Z A ^a   Ducati, R G ^a   Santos, D S ^a   Basso, L A ^a  

^a PONTIFICAL CATHOLIC UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Enzyme functional features; Enzyme structural features; Mycobacterium tuberculosis; Pyrimidine salvage pathway; Rational drug design; Tuberculosis

Indexed keywords

2 [5 [[(1,2 DIHYDRO 3 METHYL 1 OXOBENZO[F]QUINAZOLIN 9 YL)METHYL]AMINO] 1 OXO 2 ISOINDOLINYL]GLUTARIC ACID; ANTIMYCOBACTERIAL AGENT; CISPLATIN; CYTIDINE DEAMINASE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE INHIBITOR; FLUOROURACIL; NOLATREXED; NUCLEOSIDE DIPHOSPHATE KINASE; OSI 7904; PEMETREXED; PHENOLPHTHALEIN; PYRIMIDINE; PYRIMIDINE NUCLEOSIDE PHOSPHORYLASE; RALTITREXED; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG; URACIL PHOSPHORIBOSYLTRANSFERASE; URIDINE KINASE; URIDINE PHOSPHORYLASE;

ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL GENE; CRYSTAL STRUCTURE; DRUG DESIGN; DRUG SELECTIVITY; DRUG TARGETING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; HUMAN; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN FUNCTION; PYRIMIDINE METABOLISM;

CYTIDINE DEAMINASE; MYCOBACTERIUM TUBERCULOSIS; NUCLEOSIDE-DIPHOSPHATE KINASE; NUCLEOSIDE-PHOSPHATE KINASE; NUCLEOTIDE DEAMINASES; PENTOSYLTRANSFERASES; PYRIMIDINE PHOSPHORYLASES; PYRIMIDINES; PYROPHOSPHATASES; THYMIDYLATE SYNTHASE;

EID: 79952788822     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986711795029555     Document Type: Article

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