Use of a hand-portable gas chromatograph-toroidal ion trap mass spectrometer for self-chemical ionization identification of degradation products related to O-ethyl S-(2-diisopropylaminoethyl) methyl phosphonothiolate (VX)

Analytica Chimica Acta

Volumn 690, Issue 2, 2011, Pages 215-220

  Smith, Philip A ^a   Lepage, Carmela R Jackson ^b   Savage, Paul B ^c   Bowerbank, Christopher R ^d   Lee, Edgar D ^d   Lukacs, Michael J ^b  

^a Uniformed Services University of the Health Sciences and the Walter Reed National Military Medical Center   (United States)

^b DEFENCE RESEARCH AND DEVELOPMENT CANADA   (Canada)

^c Brigham Young University   (United States)

^d Torion Technologies Inc   (United States)

Author keywords

Chemical warfare agent; Field detection; Self chemical ionization; Toroidal ion trap

Indexed keywords

ANALYTES; CHEMICAL IONIZATION; CHEMICAL WARFARE AGENTS; DEGRADATION PRODUCTS; ELECTRON IONIZATION; FIELD DETECTION; GAS CHROMATOGRAPHS; ION COOLING; ION FORMATION; ION STORAGE; ION TRAP MASS SPECTROMETER; ION TRAPS; MASS SPECTRA; PHOSPHONATES; QUADRUPOLE MASS SPECTROMETRY; SELF-CHEMICAL IONIZATION; TARGET VALUES; TRIETHYLAMINES;

CHEMICAL DETECTION; CHEMICAL WARFARE; DIAGNOSTIC PRODUCTS; DIMERS; FUNCTIONAL GROUPS; GAS CHROMATOGRAPHY; INDUSTRIAL CHEMICALS; IONIZATION OF GASES; MASS SPECTROMETERS; MASS SPECTROMETRY; PHOTODEGRADATION;

IONS;

METHYLPHOSPHONOTHIOIC ACID S (2 DIISOPROPYLAMINOETHYL) O ETHYL ESTER; PHOSPHONIC ACID DERIVATIVE; TRIETHYLAMINE;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; COOLING; GAS CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; IONIZATION; PORTABLE EQUIPMENT; PRIORITY JOURNAL; PROTON TRANSPORT; REACTION TIME;

CHEMICAL WARFARE AGENTS; ETHYLAMINES; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; IONS; ORGANOTHIOPHOSPHORUS COMPOUNDS;

EID: 79952774170     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2011.02.026     Document Type: Article

References (19)

1. Eckenrode B.A. J. Am. Soc. Mass Spectrom. 2001, 12:683.
2. Groenewold G.S., Appelhans A.D., Gresham G.L., Olson J.E., Jeffery M., Wright J.B. Anal. Chem. 1999, 71:2318.
3. Petersson F., Sulzer P., Mayhew C.A., Watts P., Jordan A., Märk L., Märk T.D. Rapid Commun. Mass Spectrom. 2009, 23:3875.
4. D'Agostino P.A., Provost L.R., Visentini J. J. Chromatogr. 1987, 402:221.
5. Rohrbaugh D.K. J. Chromatogr. A 1998, 809:131.
6. Rohrbaugh D.K. J. Chromatogr. A 2000, 893:393.
7. Hook G.L., Kimm G., Koch D., Savage P.B., Ding B., Smith P.A. J. Chromatogr. A 2003, 992:1.
8. Ghaderi S.S., Kulkarni P.S., Ledford E.B.Jr., Wilkins C.L., Gross M.L. Anal. Chem. 1981, 53:428.
9. McLuckey S.A., Glish G.L., Asano K.G., Van Berkel G.J. Anal. Chem. 1988, 60:2312.
10. Pannell L.K., Pu Q.-L., Fales H.M., Mason R.T., Stephenson J.L. Anal. Chem. 1989, 61:2500.
11. Mèchin N., Plomley J., March R.E., Blasco T., Tabet J.-C. Rapid Commun. Mass Spectrom. 1995, 9:5.
12. Eichelberger J.W., Budde W.L., Slivon L.E. Anal. Chem. 1987, 59:2730.
13. Lammert S.A., Rockwood A.A., Wang M., Lee M.L., Lee E.D., Tolley S.E., Oliphant J.L., Jones J.L., Waite R.W. J. Am. Soc. Mass Spectrom. 2006, 17:916.
14. Contreras J.A., Murray J.A., Tolley S.E., Oliphant J.L., Tolley H.D., Lammert S.A., Lee E.D., Later D.W., Lee M.L. J. Am. Soc. Mass Spectrom. 2008, 19:1425.
15. Sloan K.M., Mustacich R.V., Eckenrode B.A. Field Anal. Chem. Technol. 2003, 5:288.
16. Van den Dool H., Kratz P.D. J. Chromatogr. 1963, 11:463.
17. Smith P.A., Sng M.T., Eckenrode B.A., Leow S.Y., Koch D., Erickson R.P., Jackson Lepage C.R., Hook G.L. J. Chromatogr. A 2005, 1067:285.
18. Smith P.A., Jackson Lepage C., Lukacs M., Martin N., Shufutinsky N.A., Savage P.B. Int. J. Mass Spectrom. 2010, 295:113.
19. D.K. Rohrbaugh, Mass Spectral Fragmentation of VX, Report ECBC-TR-618, Edgewood Chemical Biological Center, U.S. Army, 2008.