Increased levels of interleukin-1β and tumor necrosis factor-α in donor lungs rejected for transplantation

Journal of Heart and Lung Transplantation

Volumn 30, Issue 4, 2011, Pages 452-459

  Cypel, Marcelo ^a   Kaneda, Hiroyuki ^a   Yeung, Jonathan C ^a   Anraku, Masaki ^a   Yasufuku, Kazuhiro ^a   De Perrot, Marc ^a   Pierre, Andrew ^a   Waddell, Thomas K ^a   Liu, Mingyao ^a   Keshavjee, Shaf ^a  

^a TORONTO GENERAL HOSPITAL   (Canada)

Author keywords

biomarkers; cytokines; donor lungs; interleukin 1beta; lung transplantation; tumor necrosis alfa

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MESSENGER RNA; OXYGEN; TUMOR NECROSIS FACTOR ALPHA;

ADULT; ARTICLE; BLOOD OXYGEN TENSION; BRONCHOSCOPY; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE CLUSTER; GENE EXPRESSION; HUMAN; LUNG BIOPSY; LUNG GRAFT REJECTION; LUNG INFILTRATE; LUNG TRANSPLANTATION; LUNG VENTILATION; MALE; ORGAN PRESERVATION; PRIORITY JOURNAL; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; RETROSPECTIVE STUDY; THORAX RADIOGRAPHY;

ADULT; BIOLOGICAL MARKERS; BIOPSY, NEEDLE; FEMALE; GENE EXPRESSION; GRAFT REJECTION; HUMANS; INTERLEUKIN-1BETA; LUNG; LUNG TRANSPLANTATION; MALE; MIDDLE AGED; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79952761368     PISSN: 10532498     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.healun.2010.11.012     Document Type: Article

References (18)

1. J.D. Punch, D.H. Hayes, F.B. LaPorte, V. McBride, and M.S. Seely Organ donation and utilization in the United States, 19962005 Am J Transplant 7 2007 1327 1338 (Pubitemid 46606938)
2. J.B. Orens, A. Boehler, and M. de Perrot A review of lung transplant donor acceptability criteria J Heart Lung Transplant 22 2003 1183 1200 (Pubitemid 37324693)
3. E.P. Trulock, J.D. Christie, and L.B. Edwards Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult lung and heart-lung transplantation report-2007 J Heart Lung Transplant 26 2007 782 795 (Pubitemid 47199080)
4. J. De Meester, J. Smits, G. Persijn, and A. Haverich Listing for lung transplantation: life expectancy and transplant effect, stratified by type of end-stage lung disease, the Eurotransplant experience J Heart Lung Transplant 20 2001 518 524 (Pubitemid 32410013)
5. J.D. Christie, J.S. Sager, and S.E. Kimmel Impact of primary graft failure on outcomes following lung transplantation Chest 127 2005 161 165 (Pubitemid 41724571)
6. B.A. Whitson, M.E. Prekker, and C.S. Herrington Primary graft dysfunction and long-term pulmonary function after lung transplantation J Heart Lung Transplant 26 2007 1004 1011 (Pubitemid 47494652)
7. H. Kaneda, T.K. Waddell, and M. de Perrot Pre-implantation multiple cytokine mRNA expression analysis of donor lung grafts predicts survival after lung transplantation in humans Am J Transplant 6 2006 544 551 (Pubitemid 43382141)
8. M. Cypel, E. Yildirim, and C. Boasquevisque Donor scoring does not predict early outcome J Heart Lung Transplant 26 suppl 1 2008 S212 S213
9. L.B. Ware, Y. Wang, and X. Fang Assessment of lungs rejected for transplantation and implications for donor selection Lancet 360 2002 619 620 (Pubitemid 35232198)
10. M. de Perrot, Y. Sekine, and S. Fischer Interleukin-8 release during early reperfusion predicts graft function in human lung transplantation Am J Respir Crit Care Med 165 2002 211 215 (Pubitemid 34084460)
11. A.J. Fisher, S.C. Donnelly, and N. Hirani Elevated levels of interleukin-8 in donor lungs is associated with early graft failure after lung transplantation Am J Respir Crit Care Med 163 2001 259 265 (Pubitemid 32095278)
12. M. Anraku, M.J. Cameron, and T.K. Waddell Impact of human donor lung gene expression profiles on survival after lung transplantation: a case-control study Am J Transplant 8 2008 2140 2148
13. M. Ray, S. Dharmarajan, J. Freudenberg, W. Zhang, and G.A. Patterson Expression profiling of human donor lungs to understand primary graft dysfunction after lung transplantation Am J Transplant 7 2007 2396 2405 (Pubitemid 47347845)
14. S. Rozen, and H. Skaletsky Primer3 on the WWW for general users and for biologist programmers Methods Mol Biol 132 2000 365 386
15. R. Ingemansson, A. Eyjolfsson, and L. Mared Clinical transplantation of initially rejected donor lungs after reconditioning ex vivo Ann Thorac Surg 87 2009 255 260
16. M. Cypel Technique for prolonged normothermic ex vivo lung perfusion J Heart Lung Transplant 27 2008 1319 1325
17. M. Cypel, M. Rubacha, and J. Yeung Normothermic ex vivo perfusion prevents lung injury compared to extended cold preservation for transplantation Am J Transplant 9 2009 2262 2269
18. M. Cypel, M. Liu, and M. Rubacha Functional Repair of Human Donor Lungs by IL-10 Gene Therapy Sci Transl Med 1 2009 1 9