Antipsychotic prescribing to older people living in care homes and the community in England and Wales

International Journal of Geriatric Psychiatry

Volumn 26, Issue 4, 2011, Pages 423-434

  Shah, S M ^a   Carey, I M ^a   Harris, T ^a   DeWilde, S ^a   Cook, D G ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

Author keywords

Antipsychotics; Care homes; Nursing homes; Older people

Indexed keywords

AMISULPRIDE; ARIPIPRAZOLE; CHLORPROMAZINE; HALOPERIDOL; LEVOMEPROMAZINE; NEUROLEPTIC AGENT; OLANZAPINE; PERICIAZINE; PERPHENAZINE; PROMAZINE; QUETIAPINE; RISPERIDONE; SULPIRIDE; TRIFLUOPERAZINE;

AGED; ARTICLE; DATA BASE; DEMENTIA; GERIATRIC PATIENT; HUMAN; MAJOR CLINICAL STUDY; MENTAL DISEASE; NURSING HOME; PRESCRIPTION; RESIDENTIAL HOME; UNITED KINGDOM;

AGED; AGED, 80 AND OVER; ANTIPSYCHOTIC AGENTS; COMMUNITY HEALTH SERVICES; ENGLAND; FEMALE; HOMES FOR THE AGED; HUMANS; MALE; NURSING HOMES; PHYSICIAN'S PRACTICE PATTERNS; PSYCHOTIC DISORDERS; WALES;

EID: 79952756564     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.2557     Document Type: Article

References (35)

1. Alldred DP, Petty DR, Bowie P, Zermansky AG, Raynor DK. 2007. Antipsychotic prescribing patterns in care homes and relationship with dementia. Psychiatr Bull 31: 329-332. (Pubitemid 47399290)
2. Ballard C, Hanney ML, Theodoulou M, et al. 2009. The dementia antipsychotic withdrawal trial (DART-AD): long-term follow-up of a randomised placebo-controlled trial. Lancet Neurol 8: 151-157.
3. Banerjee S. 2009. The use of antipsychotic medication for people with dementia: Time for action. A report for the Minister of State for Care Services Department of Health: London.
4. Beers MH, Avorn J, Soumerai SB, Everitt D, Sherman DS, et al. 1988. Psychoactive medication use in intermediate-care facilities. JAMA 260: 3016-3020. (Pubitemid 19003116)
5. Bourke HD, Robinson M. 2004. Feasibility study and methodology to create a quality-evaluated database of primary care data. Inform Prim Care 12: 171-177. (Pubitemid 39534583)
6. Committee on Safety of Medicines. 2006. Atypical antipsychotic drugs and stroke: message from Professor Gordon Duff, chairman, (CEM/CMO/2004/1). London: Committee on Safety of Medicines.
7. Connely PJ, Law E, Angus S, Prentice N. 2010. Fifteen year comparison of antipsychotic use in people with dementia within hospital and nursing home settings: sequential cross-sectional study. Int J Geriatr Psychiatry 25: 160-165.
8. Department for Communities and Local Government. 2008. The English Indices of Deprivation 2007. London.
9. Department of Health. 2006. New GMS Contract QOF Implementation. Dataset and Business Rules. Department of Health. London
10. Department of Health. 2009. Living well with dementia: a National Dementia strategy.
11. Douglas IJ, Smeeth L. 2008. Exposure to antipsychotics and risk of stroke: self-controlled case series study. BMJ 337: a1227-a1227.
12. Fahey T, Montgomery AA, Barnes J, et al. 2003. Quality of care for elderly residents in nursing homes and elderly people living at home: controlled observational study. BMJ 326: 580.
13. Feng Z, Hirdes JP, Smith TF, Finne-Soveri H, et al. 2009. Use of physical restraints and antipsychotic medications in nursing homes: a cross-national study. Int J Geriatr Psychiatry 24: 1110-1118.
14. Fossey J, Ballard C, Juszczak E, et al. 2006. Effect of enhanced psychosocial care on people with severe dementia: cluster randomised trial of antipsychotic use in nursing home residents. Br Med J 332: 756-761.
15. Hanley JA, Negassa A, Edwardes MD, Forrester JE. 2003. Statistical Analysis of Correlated Data Using Generalized Estimating Equations: An Orientation Am J Epidemiol 157: 364-375. (Pubitemid 36196757)
16. Hardy JR, Leaderer BP, Holford TR, Hall GC, Bracken MB. 2006. Safety of medications prescribed before and during early pregnancy in a cohort of 81,975 mothers from the UK General Practice Research Database. Pharmacoepidemiol Drug Saf 15: 555-564. (Pubitemid 44336270)
17. Kamble P, Chen H, Sherer J, Aparasu RR. 2008. Antipsychotic drug use among elderly nursing home residents in the United States. Am J Geriatr Pharmacother 6: 187-197.
18. Lewis JD, Schinnar R, Bilker WB, Wang X, Strom BL. 2007. Validation studies of the health improvement network (THIN) data base for pharmacoepidemiology research. Pharmacoepidemiol Drug Saf 16: 393-401. (Pubitemid 46656860)
19. Lindesay J, Matthews R, Jagger C. 2003. Factors associated with antipsychotic drug use in residential care: changes between 1990 and 1997. Int J Geriatr Psychiatry 18: 511-519. (Pubitemid 36763654)
20. Lövheim H, Sandman PO, Kallin K, Karlsson S, Gustafson Y. 2008. Symptoms of mental health and psychotropic drug use among old people in geriatric care, changes between 1982 and 2000. Int J Geriatr Psychiatry 23: 289-294. (Pubitemid 351404024)
21. Macfarlane A, Hockley C, McCandlish R, McNiece R. 2002. Can the General Practice Research Database be used to monitor the health of babies and their mothers. Health Stat Q 13: 5-15.
22. Mcgrath A, Jackson G. 1996. Survey of neuroleptic prescribing in residents of nursing homes in Glasgow. BMJ 312: 611-612. (Pubitemid 26079597)
23. NICE/SCIE. 2006. Dementia - Supporting People with Dementia and Their Carers in Health and Social Care. NICE/SCIE: London.
24. Oborne C, Hooper R, Li K, Swift C, Jackson S. 2002. An indicator of appropriate neuroleptic prescribing in nursing homes. Age Ageing 31: 435-439. (Pubitemid 35452787)
25. O'Brien J. 2008. Antipsychotics for people with dementia. BMJ 337: a602.
26. ONS. 2001. Psychiatric morbidity among adults living in private households, 2000. Office for National Statistics, London.
27. ONS. 2009. General Household Survey, 2007. Office of National Statistics. London.
28. Ray WA, Federspiel CF, Schaffner W. 1980. A study of antipsychotic drug use in nursing homes: epidemiologic evidence suggesting misuse. Am J Public Health 170: 485-491. (Pubitemid 10098089)
29. Rochon PA, Stukel TA, Bronskill SE, et al. 2007. Variation in Nursing Home Antipsychotic Prescribing Rates. Arch Intern Med 167: 676-683. (Pubitemid 46598460)
30. Schneider LS, Dagerman K, Insel PS. 2006. Efficacy and adverse effects of atypical antipsychotics for dementia: meta-analysis of randomized, placebo-controlled trials. Am J Geriatr Psychiatry 14: 191-210.
31. Schneider LS, Dagerman KS, Insel P. 2005. Risk of death with atypical antipsychotic drug treatment for dementia: meta-analysis of randomized placebo-controlled trials. JAMA 294: 1934-1943. (Pubitemid 41464695)
32. Sink KM, Holden KF, Yaffe K. 2005. Pharmacological treatment of neuropsychiatric symptoms of dementia: a review of the evidence. JAMA 293: 596-608. (Pubitemid 40171242)
33. Snowdon J, Day S, Baker W. 2005. Why and how antipsychotic drugs are used in 40 Sydney nursing homes. Int J Geriatr Psychiatry 20: 1146-1152.
34. Shah SM, Carey IM, Harris T, et al. 2010. Identifying the clinical characteristics of older people living in care homes using a novel approach in a primary care database. Age & Ageing Advance Access published on July 16, 2010. DOI: 10.1093/ageing/afq086
35. Waldemar G, Phung TT, Burns A, et al. 2007. Access to diagnostic evaluation and treatment for dementia in Europe. Int J Geriatr Psychiatry. 22: 47-54. (Pubitemid 46117337)