Preparation and biological evaluation of multifunctional PLGA-nanoparticles designed for photoacoustic imaging

Nanomedicine: Nanotechnology, Biology, and Medicine

Volumn 7, Issue 2, 2011, Pages 228-237

  Kohl, Yvonne ^a   Kaiser, Christian ^b   Bost, Wolfgang ^a   Stracke, Frank ^a   Fournelle, Marc ^a   Wischke, Christian ^b   Thielecke, Hagen ^a   Lendlein, Andreas ^b   Kratz, Karl ^b   Lemor, Robert ^a  

^a FRAUNHOFER INSTITUTE FOR BIOMEDICAL ENGINEERING   (Germany)

^b INSTITUTE OF MATERIALS RESEARCH   (Germany)

Author keywords

Cytotoxicity; NIR active particles; Photoacoustic imaging; Resorbable nanoparticles; Spray drying

Indexed keywords

1064 NM; BIOLOGICAL EVALUATION; CONTRAST AGENT; CYTOTOXIC EFFECTS; DIAGNOSTIC APPLICATIONS; DIFFERENT SIZES; ENCAPSULATION EFFICIENCY; GLYCOLIDE; GOOD YIELD; HIGH RESOLUTION; HUMAN HEPATOCARCINOMA; IN-VITRO; LASER LIGHTS; MITOCHONDRIAL ACTIVITY; MOLECULAR IMAGING; MONKEY KIDNEY CELLS; MULTI-FUNCTIONAL NANOPARTICLES; NANO PARTICULATES; ND : YAG LASERS; NEAR-INFRARED ABSORPTION; NEAR-INFRARED DYES; NEW MODALITY; NIR-ACTIVE PARTICLES; PARTICLE CONCENTRATIONS; PHOTOACOUSTIC IMAGING; PHOTOACOUSTICS; PLGA NANOPARTICLES; POLY(RAC-LACTIDE); POLYMER PARTICLES; RESORBABLE; SPHERICAL NANOPARTICLES; SPRAY DRYING PROCESS; SUBMICRON-SIZED;

ANIMAL CELL CULTURE; CELL CULTURE; CELL DEATH; CENTRIFUGATION; CYTOTOXICITY; DRYING; ENCAPSULATION; GENE TRANSFER; INFRARED DEVICES; INFRARED LASERS; NANOPARTICLES; NEODYMIUM; NEODYMIUM LASERS; PHOTOACOUSTIC EFFECT; SPRAY DRYING; ULTRASONIC APPLICATIONS;

INFRARED DRYING;

DYE; NANOPARTICLE; POLYGLACTIN;

ABSORPTION SPECTROSCOPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL STRAIN HEPG2; CELL VIABILITY; CONTRAST ENHANCEMENT; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; INCUBATION TIME; KIDNEY CELL; MOLECULAR IMAGING; NANOENCAPSULATION; NEODYMIUM LASER; NONHUMAN; PARTICLE SIZE; SCANNING ELECTRON MICROSCOPY; SPRAY DRYING; ULTRACENTRIFUGATION;

ACOUSTICS; ANIMALS; CELL SURVIVAL; CERCOPITHECUS AETHIOPS; CONTRAST MEDIA; DRUG CARRIERS; HEP G2 CELLS; HUMANS; LACTIC ACID; LASERS, SOLID-STATE; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; PARTICLE SIZE; POLYGLYCOLIC ACID; SPECTROSCOPY, NEAR-INFRARED; ULTRASONOGRAPHY; VERO CELLS;

EID: 79952753712     PISSN: 15499634     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nano.2010.07.006     Document Type: Article

References (49)

1. Bost W., Lemor R.M. Photoacoustic microscopy for high-resolution imaging. J Acoust Soc Am 2008, 123:3370-3375.
2. Fournelle M., Maass K., Fonfara H., Welsch H.J., Hewener H., Gunther C., et al. Real-time optoacoustic imaging using near infrared absorbing gold nanoshells for contrast enhancement. IEEE Ultrasonics Symp. Proc 2007, 1:2417-2420.
3. Harrison T., Ranasinghesagara J.C., Lu H.H., Mathewson K., Walsh A., Zemp R.J. Combined photoacoustic and ultrasound biomicroscopy. Optics Express 2009, 17:22041-22046.
4. Li C.H., Wang L.H.V. Photoacoustic tomography and sensing in biomedicine. Phys Med Biol 2009, 54:59-97.
5. Xu M.H., Wang L.H.V. Photoacoustic imaging in biomedicine. Rev Sci Instrum 2006, 77:041101. 10.1063/1.2195024.
6. Agarwal A., Huang S.W., O'Donnell M., Day K.C., Day M., Kotov N., et al. Targeted gold nanorod contrast agent for prostate cancer detection by photoacoustic imaging. J Appl Phys 2007, 102:064701. 10.1063/1.2777127.
7. Bost W., Stracke F., Weiss E.C., Narasimhan S., Kolios M.C., Lemor R. High frequency optoacoustic microscopy. Conf Proc IEEE Eng Med Biol Soc 2009, 1:5883-5886.
8. Kim J.W., Galanzha E.I., Shashkov E.V., Moon H.M., Zharov V.P. Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents. Nat Nanotechnol 2009, 4:688-694.
9. Shashkov E.V., Everts M., Galanzha E.I., Zharov V.P. Quantum dots as multimodal photoacoustic and photothermal contrast agents. Nano Lett 2008, 8:3953-3958.
10. Chen W.R., Adams R.L., Higgins A.K., Bartels K.E., Nordquist R.E. Photothermal effects on murine mammary tumors using indocyanine green and an 808-nm diode laser: an in vivo efficacy study. Cancer Lett 1996, 98:169-173.
11. Saxena V., Sadoqi M., Shao J. Enhanced photo-stability, thermal-stability and aqueous-stability of indocyanine green in polymeric nanoparticulate systems. J Photochem Photobiol 2004, 74:29-38.
12. Saxena V., Sadoqi M., Shao J. Indocyanine green-loaded biodegradable nanoparticles: preparation, physicochemical characterization and in vitro release. Int J Pharm 2004, 278:293-301.
13. McDonald A., Claffey N., Pearson G., Blau W., Setchell D. The effect of Nd: YAG radiation at nanosecond pulse duration on dentine crater depth. Biomaterials 2002, 23:51-58.
14. Lewinski N., Colvin V., Drezek R. Cytotoxicity of nanoparticles. Small 2008, 4:26-49.
15. Murthy S.K. Nanoparticles in modern medicine: state of the art and future challenges. Int J Nanomed 2007, 2:129-141.
16. Wagner V., Dullaart A., Bock A.K., Zweck A. The emerging nanomedicine landscape. Nat Biotechnol 2006, 24:1211-1217.
17. Goodman C.M., McCusker C.D., Yilmaz T., Rotello V.M. Toxicity of gold nanoparticles functionalized with cationic and anionic side chains. Bioconjug Chem 2004, 15:897-900.
18. Pan Y., Neuss S., Leifert A., Fischler M., Wen F., Simon U., et al. Size-dependent cytotoxicity of gold nanoparticles. Small 2007, 3:1941-1949.
19. Shah N., Chaudhari K., Dantuluri P., Murthy R.S., Das S. Paclitaxel-loaded PLGA nanoparticles surface modified with transferrin and Pluronic((R))P85, an in vitro cell line and in vivo biodistribution studies on rat model. J Drug Target 2009, 17:533-542.
20. Lendlein A, Kelch S. Degradable, multifunctional polymeric biomaterials with shape-memory. Functionally Graded Mater VIII. 2005;492:219-23.
21. Behl M., Razzaq M.Y., Lendlein A. Multifunctional shape-memory polymers. Adv Mater 2010, 22:3388-3410. (doi: 10.1002/adma.200904447).
22. Cartiera M.S., Johnson K.M., Rajendran V., Caplan M.J., Saltzman W.M. The uptake and intracellular fate of PLGA nanoparticles in epithelial cells. Biomaterials 2009, 30:2790-2798.
23. Cheng F.Y., Wang S.P.H., Su C.H., Tsai T.L., Wu P.C., Shieh D.B., et al. Stabilizer-free poly(lactide-co-glycolide) nanoparticles for multimodal biomedical probes. Biomaterials 2008, 29:2104-2112.
24. Hans M.L., Lowman A.M. Biodegradable nanoparticles for drug delivery and targeting. Curr Opin Solid State Mater Sci 2002, 6:319-327.
25. Lim Y.T., Noh Y.W., Han J.H., Cai Q.Y., Yoon K.H., Chung B.H. Biocompatible polymer-nanoparticle-based bimodal imaging contrast agents for the labeling and tracking of dendritic cells. Small 2008, 4:1640-1645.
26. Ravi Kumar M.N.V., Bakowsky U., Lehr C.M. Preparation and characterization of cationic PLGA nanospheres as DNA carriers. Biomaterials 2004, 25:1771-1777.
27. Soppimath K.S., Aminabhavi T.M., Kulkarni A.R., Rudzinski W.E. Biodegradable polymeric nanoparticles as drug delivery devices. J Control Release 2001, 70:1-20.
28. Weigel T., Schinkel G., Lendlein A. Design and preparation of polymeric scaffolds for tissue engineering. Expert Rev Med Devices 2006, 3:835-851.
29. Wischke C., Schwendeman S.P. Principles of encapsulating hydrophobic drugs in PLA/PLGA microparticles. Int J Pharm 2008, 364:298-327.
30. Wischke C., Zimmermann J., Wessinger B., Schendler A., Borchert H.H., Peters J.H., et al. Poly(I:C) coated PLGA microparticles induce dendritic cell maturation. Int J Pharm 2009, 365:61-68.
31. Casalboni M., De Matteis F., Prosposito P., Pizzoferrato R. Optical investigation of infrared dyes in hybrid thin films. Appl Phys Lett 1999, 75:2172-2174.
32. Casalboni M., DeMatteis F., Francini R., Prosposito P., Senesi R., Grassano U.M., et al. Optical properties of dye-doped sol-gel glasses. J Luminescence 1997, 72:475-477.
33. Kranitzky W., Kopainsky B., Kaiser W., Drexhage K.H., Reynolds G.A. A new infrared laser dye of superior photostability tunable to 1.24 μm with picosecond excitation. Optics Commun 1981, 36:149-152.
34. Pizzoferrato R., Casalboni M., De Matteis F., Prosposito P. Optical investigation of infrared dyes in sol-gel films. J Luminescence 2000, 87:748-750.
35. Tosi G., Vergoni A.V., Ruozi B., Bondioli L., Badiali L., Rivasi F., et al. Sialic acid and glycopeptides conjugated PLGA nanoparticles for central nervous system targeting: in vivo pharmacological evidence and biodistribution. J Control Release 2010, 145:49-57.
36. Maulding H.V., Tice T.R., Cowsar D.R., Fang J.W., Pearson J.E., Nazarene J.P. Biodegradable microcapsules: acceleration of polymeric excipient hydrolytic rate by incorporation of a basic medicament. J Control Release 1986, 103-117.
37. Song C.X., Labhasetwar V., Murphy H., Qu X., Humphrey W.R., Shebuski R.J., et al. Formulation and characterization of biodegradable nanoparticles for intravascular local drug delivery. J Control Release 1997, 43:197-212.
38. Leelarasamee N., Howard S.A., Malanga C.J., Luzzi L.A., Hogan T.F., Kandzari S.J., et al. Kinetics of drug release from polylactic acid-hydrocortisone microcapsules. J Microencapsul 1986, 3:171-179.
39. Bodmeier R., Chen H. Preparation of biodegradable poly(±)lactide microparticles using a spray-drying technique. J Pharm Pharmacol 1988, 754-757.
40. Reich G. Ultrasound-induced degradation of PLA and PLGA during microsphere processing: influence of formulation variables. Eur J Pharm Biopharm 1998, 45:165-171.
41. Choa F.S., Liu Y., Liu P.L. Continuous-wave synchronously pumped femtosecond dye-laser at 1.3-Mu-M. Optics Lett 1989, 14:222-223.
42. Kopainsky B., Qiu P., Kaiser W., Sens B., Drexhage K.H. Lifetime, photostability, and chemical-structure of Ir heptamethine cyanine dyes absorbing beyond 1 Mu-Mm. Appl Phys B-Photophys Laser Chem 1982, 29:15-18.
43. Lobentanzer H., Polland H.J. Generation of tunable picosecond pulses between 1.18 Mu-M and 1.53 Mu-M in a ring laser configuration using dye no. 5. Optics Commun 1987, 62:35-38.
44. Zweers M.L.T., Engbers G.H.M., Grijpma D.W., Feijen J. In vitro degradation of nanoparticles prepared from polymers based on dl-lactide, glycolide and poly(ethylene oxide). J Control Release 2004, 100:347-356.
45. Holzer W., Mauerer M., Penzkofer A., Szeimies R.M., Abels C., Landthaler M., et al. Photostability and thermal stability of indocyanine green. J Photochem Photobiol B 1998, 47:155-164.
46. Saxena V., Sadoqi M., Shao J. Degradation kinetics of indocyanine green in aqueous solution. J Pharm Sci 2003, 92:2090-2097.
47. Couzinet S., Cejas E., Schittny J., Deplazes P., Weber R., Zimmerli S. Phagocytic uptake of Encephalitozoon cuniculi by nonprofessional phagocytes. Infect Immun 2000, 68:6939-6945.
48. Johnston H.J., Semmler-Behnke M., Brown D.M., Kreyling W., Tran L., Stone V. Evaluating the uptake and intracellular fate of polystyrene nanoparticles by primary and hepatocyte cell lines in vitro. Toxicol Appl Pharmacol 2010, 242:66-78.
49. Steffan A.M., Gendrault J.L., McCuskey R.S., McCuskey P.A., Kirn A. Phagocytosis, an unrecognized property of murine endothelial liver cells. Hepatology 1986, 6:830-836.