Topology of protein interaction network shapes protein abundances and strengths of their functional and nonspecific interactions

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 10, 2011, Pages 4258-4263

  Heo, Muyoung ^a   Maslov, Sergei ^b   Shakhnovich, Eugene ^a  

^a HARVARD UNIVERSITY   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

A multi scale evolutionary model cell; Evolution of protein interface; Genotype phenotype relationship

Indexed keywords

PROTEOME;

ARTICLE; COPY NUMBER VARIATION; GENE MUTATION; GENOTYPE; HYDROPHOBICITY; MASS SPECTROMETRY; PHENOTYPE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; SIMULATION; YEAST;

MUTATION; PROTEIN BINDING; PROTEINS;

EID: 79952744659     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1009392108     Document Type: Article

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