Data mining methods for classification of Medium-Chain Acyl-CoA dehydrogenase deficiency (MCADD) using non-derivatized tandem MS neonatal screening data

Journal of Biomedical Informatics

Volumn 44, Issue 2, 2011, Pages 319-325

  Van den Bulcke, Tim ^a   Broucke, Paul Vanden ^a   Hoof, Viviane Van ^a,b,c   Wouters, Kristien ^a   Broucke, Seppe Vanden ^a   Smits, Geert ^a   Smits, Elke ^a   Proesmans, Sam ^c   Genechten, Toon Van ^c   Eyskens, François ^a,b,c  

^a ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^b Provinciaal Centrum voor de Opsporing van Metabole Aandoeningen (PCMA)   (Belgium)

^c UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

Data mining; Logistic regression; MCADD; Medium Chain Acyl CoA dehydrogenase; Rare diseases

Indexed keywords

BELGIUM; BLOOD SAMPLES; CLASSIFICATION ACCURACY; CROSS VALIDATION; DATA MINING METHODS; DATA SETS; EARLY DETECTION; FATTY ACID OXIDATION; GRID SEARCH; INTERPRETABILITY; LOGISTIC REGRESSION; LOGISTIC REGRESSIONS; MACHINE LEARNING METHODS; MCADD; MEDIUM-CHAIN ACYL-COA DEHYDROGENASE; METABOLIC DISEASE; METABOLIC DISORDERS; MODEL PARAMETERS; NEWBORN SCREENING; POSITIVE PREDICTIVE VALUES; POTENTIAL VALUES; RARE DISEASE; SCREENING DATA; SCREENING METHODS; SUPPORT TOOL; TANDEM MASS SPECTROMETRY; TANDEM MS; TEST SETS; THRESHOLD OPTIMIZATION; VARIABLE SELECTION;

CLASSIFICATION (OF INFORMATION); DATA MINING; DECISION TREES; DIAGNOSIS; DISEASES; FATTY ACIDS; LEARNING SYSTEMS; MASS SPECTROMETRY; METABOLISM; OPTIMIZATION;

REGRESSION ANALYSIS;

ACYLCARNITINE; CARNITINE; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE;

ARTICLE; BELGIUM; DATA MINING; DECISION TREE; DIAGNOSTIC TEST ACCURACY STUDY; DIAGNOSTIC VALUE; DISEASE CLASSIFICATION; EARLY DIAGNOSIS; HUMAN; LOGISTIC REGRESSION ANALYSIS; MACHINE LEARNING; MAJOR CLINICAL STUDY; MEDIUM CHAIN ACYL COENZYME A DEHYDROGENASE DEFICIENCY; MULTIPLE ACYL COA DEHYDROGENASE DEFICIENCY; NEWBORN SCREENING; PREDICTIVE VALIDITY; PRIORITY JOURNAL; RIDGE LOGISTIC REGRESSION; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS; TANDEM MASS SPECTROMETRY;

ACYL-COA DEHYDROGENASE; ARTIFICIAL INTELLIGENCE; BELGIUM; DATA MINING; HUMANS; INFANT, NEWBORN; LIPID METABOLISM, INBORN ERRORS; NEONATAL SCREENING; TANDEM MASS SPECTROMETRY;

EID: 79952741160     PISSN: 15320464     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbi.2010.12.001     Document Type: Article

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