Association between T-lymphocyte regulatory gene CTLA4 single nucleotide polymorphism at position 49 in exon 1 and HLA-DRB1 08 in Japanese patients with psoriasis vulgaris

Journal of Dermatological Science

Volumn 62, Issue 1, 2011, Pages 70-71

  Muto, Masahiko ^a   Deguchi, Hirotaka ^a   Tanaka, Akemi ^a   Inoue, Takayuki ^a   Ichimiya, Makoto ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; GENOMIC DNA; HLA DR ANTIGEN; IMMUNOGLOBULIN G ANTIBODY;

ADOLESCENT; ADULT; AGED; CONTROLLED STUDY; DISEASE PREDISPOSITION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; IMMUNE RESPONSE; IMMUNOGLOBULIN BLOOD LEVEL; LETTER; MAJOR CLINICAL STUDY; MALE; ONSET AGE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PSORIASIS VULGARIS; REGULATORY T LYMPHOCYTE; SINGLE NUCLEOTIDE POLYMORPHISM; STREPTOCOCCUS INFECTION; STREPTOCOCCUS PYOGENES;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD; EXONS; FEMALE; GENOTYPE; HLA-DR ANTIGENS; HUMANS; JAPAN; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PSORIASIS; T-LYMPHOCYTES;

EID: 79952738436     PISSN: 09231811     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2010.10.012     Document Type: Letter

References (10)

1. Nestle F.O., Kaplan D.H., Barker J. Psoriasis mechanisms of disease. N Engl J Med 2009, 361:496-509.
2. Kristiansen O.P., Larsen Z.M., Pociot F. CTLA-4 in autoimmune diseases-a general susceptibility gene to autoimmunity?. Genes Immun 2000, 1:170-184.
3. Tsunemi Y., Saeki H., Kishimoto M., Mitsui H., Tada Y., Torii H., et al. Cytotoxic T lymphocyte antigen-4 gene (CTLA4) polymorphisms in Japanese patients with psoriasis vulgaris. J Dermatol Sci 2003, 32:163-165.
4. Kim Y.-K., Pyo C.-W., Hur S.-S., Kim T.-Y., Kim T.-G. No associations of CTLA-4 and ICAM-1 polymorphisms with psoriasis in the Korean population. J Dermatol Sci 2003, 33:75-77.
5. Łuszczek W., Kubicka W., Jasek M., Barant E., Cisło M., Nockowski P., et al. CTLA-4 gene polymorphisms and natural soluble CTLA-4 protein in psoriasis vulgaris. Int J Immunogenet 2006, 33:217-224.
6. Alenius G.-M., Friberg C., Nilsson S., Wahlström J., Dahlqvist S.R., Samuelsson L. Analysis of 6 genetic loci for disease susceptibility in psoriatic arthritis. J Rheumatol 2004, 31:2230-2235.
7. Nakagawa H., Akazaki S., Asahina A., Tokunaga K., Matsuki K., Kuwata S., et al. Study of HLA class I, class II and complement genes (C2, C4A, C4B and BF) in Japanese psoriatics and analysis of a newly-found high-risk haplotype by pulsed field gel electrophoresis. Arch Dermatol Res 1991, 283:281-284.
8. Muto M., Date Y., Ichimiya M., Moriwaki Y., Mori K., Kamikawaji N., et al. Significance of antibodies to streptococcal M protein in psoriatic arthritis and their association with HLA-A*0207. Tissue Antigens 1996, 48:645-650.
9. Łuszczek W., Majorczyk E., Nockowski P., Plucinśki P., Jasek M., Nowak I., et al. Distribution of the CTLA-4 single nucleotide polymorphism CT60G>A and +49A>G in psoriasis vulgaris patients and control individuals from a Polish Caucasian population. Int J Immunogenet 2007, 35:51-55.
10. Kouki T., Sawai Y., Gardine C.A., Fisfalen M.-E., Alegre M.-L., DeGroot L.J. CTLA-4 gene polymorphism at position 49 in exon1 reduces the inhibitory function of CTLA-4 and contributes to the pathogenesis of Graves' disease. J Immunol 2000, 165:6606-6611.