Aphasia and neglect are uncommon in cerebellar disease: Negative findings in a prospective study in acute cerebellar stroke

Cerebellum

Volumn 9, Issue 4, 2010, Pages 556-566

  Frank, Benedikt ^a   Maschke, Matthias ^a,d   Groetschel, Hanjo ^a   Berner, Maike ^c   Schoch, Beate ^a   Hein Kropp, Christoph ^a   Gizewski, Elke Ruth ^a   Ziegler, Wolfram ^b   Karnath, Hans Otto ^c,e   Timmann, Dagmar ^a  

^a UNIVERSITY OF DUISBURG ESSEN   (Germany)

^b KLINIKUM BOGENHAUSEN   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d Central Interdisciplinary Ultrasound Municipal Hospital Trier Barmherzige Brüder   (Germany)

^e GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

Cerebellum; Cognition; Language; Non motor; Visuospatial

Indexed keywords

ADULT; AGED; APHASIA; ARTICLE; BRAIN ISCHEMIA; BRAIN REGION; CEREBELLAR ATAXIA; CEREBELLUM INFARCTION; CEREBELLUM INJURY; CEREBROVASCULAR ACCIDENT; CLINICAL ARTICLE; COMMUNICATION DISORDER; CONTROLLED STUDY; DEPTH PERCEPTION; DYSGRAPHIA; DYSLEXIA; FEMALE; HUMAN; MALE; NEGLECT; NEUROIMAGING; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; PROSPECTIVE STUDY; RESPONSE TIME; TASK PERFORMANCE; VERBAL BEHAVIOR; VISUAL DISORDER;

ADULT; AGED; APHASIA; BRAIN MAPPING; CEREBELLUM; FEMALE; FUNCTIONAL LATERALITY; HUMANS; LANGUAGE; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROPSYCHOLOGICAL TESTS; PERCEPTUAL DISORDERS; PROSPECTIVE STUDIES; PSYCHOMOTOR PERFORMANCE; REACTION TIME; STROKE; VERBAL BEHAVIOR; YOUNG ADULT;

EID: 79952736455     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1007/s12311-010-0197-2     Document Type: Article

References (40)

1. Middleton FA, Strick PL. Cerebellar projections to the prefrontal cortex of the primate. J Neurosci. 2001;21(2):700-12. (Pubitemid 32107458)
2. Ramnani N, Behrens TE, Johansen-Berg H, Richter MC, Pinsk MA, Andersson JL, et al. The evolution of prefrontal inputs to the cortico-pontine system: diffusion imaging evidence from Macaque monkeys and humans. Cereb Cortex. 2006;16(6):811-8.
3. Stoodley CJ, Schmahmann JD. Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies. Neuroimage. 2009;44(2):489-501.
4. Timmann D, Daum I. Cerebellar contributions to cognitive functions: a progress report after two decades of research. Cerebellum. 2007;6(3):159-62. (Pubitemid 47360072)
5. Frank B, Schoch B, Richter S, Frings M, Karnath HO, Timmann D. Cerebellar lesion studies of cognitive function in children and adolescents - limitations and negative findings. Cerebellum. 2007;6:1-12.
6. Schmahmann JD. Disorders of the cerebellum: ataxia, dysmetria of thought and the cerebellar cognitive affective syndrome. J Neuropsychiatry Clin Neurosci. 2004;16(3):367-78. (Pubitemid 39244566)
7. Justus T. The cerebellum and English grammatical morphology: evidence from production, comprehension, and grammaticality judgments. J Cogn Neurosci. 2004;16(7):1115-30. (Pubitemid 39274441)
8. Marien P, Engelborghs S, Fabbro F, De Deyn PP. The lateralized linguistic cerebellum: a review and a new hypothesis. Brain Lang. 2001;79:580-600. (Pubitemid 34093722)
9. Schmahmann JD, Sherman JC. The cerebellar cognitive affective syndrome. Brain. 1998;121:561-79. (Pubitemid 28162120)
10. Silveri MC, Leggio MG, Molinari M. The cerebellum contributes to linguistic production: a case of agrammatic speech following a right cerebellar lesion. Neurology. 1994;44(11):2047-50. (Pubitemid 24349503)
11. Frank B, Schoch B, Hein-Kropp C, Hövel M, Gizewski E, Karnath HO, et al. Aphasia, neglect and extinction are no prominent clinical signs in children and adolescents with acute surgical cerebellar lesions. Exp Brain Res. 2008;184:511-9.
12. Richter S, Gerwig M, Aslan B, Wilhelm H, Schoch B, Dimitrova A, et al. Cognitive functions in patients with MR-defined chronic focal cerebellar lesions. J Neurol. 2007;254:1193-203. (Pubitemid 350112346)
13. Richter S, Schoch B, Kaiser O, Groetschel H, Hein-Kropp C, Maschke M, et al. Children and adolescents with chronic cerebellar lesions show no clinically relevant signs of aphasia or neglect. J Neurophysiol. 2005;94(6):4108-20. (Pubitemid 41691772)
14. Richter S, Kaiser O, Hein-Kropp C, Dimitrova A, Gizewski E, Beck A, et al. Preserved verb generation in patients with cerebellar atrophy. Neuropsychologia. 2004;42(9):1235-46. (Pubitemid 38737100)
15. Frank B, Schoch B, Hein-Kropp C, Dimitrova A, Hovel M, Ziegler W, et al. Verb generation in children and adolescents with acute cerebellar lesions. Neuropsychologia. 2007;45(5):977-88. (Pubitemid 44958772)
16. Oldfield RC. The assessment and analysis of handedness: the Edinburgh inventory. Neuropsychologia. 1971;9(1):97-113.
17. Trouillas P, Takayanagi T, Currier RD, Subramony SH, Wessel K, et al. International cooperative ataxia rating scale for pharmacological assessment of the cerebellar syndrome. The Ataxia Neuropharmacology Committee of the World Federation of Neurology. J Neurol Sci. 1997;145(2):205-11. (Pubitemid 27121687)
18. Hautzinger M, Bailer M. Allgemeine depressions-skala, manual. Weinheim: Beltz Test GmbH; 1993.
19. Schmahmann JD, Dojon J, Toga AW, Petrides M, Evans AC. MRI atlas of the human cerebellum. San Diego: Academic; 2000.
20. Luft AR, Skalej M, Stefanou A, Klose U, Voigt K. Comparing motion- and imagery-related activation in the human cerebellum: a functional MRI study. Hum Brain Mapp. 1998;6(2):105-13. (Pubitemid 28146509)
21. Dimitrova A, Weber J, Redies C, Kindsvater K, Maschke M, Kolb FP, et al. MRI atlas of the human cerebellar nuclei. Neuroimage. 2002;17(1):240-55.
22. Huber W, Poeck K, Weniger D, Willmes K. Aachener aphasie test (AAT). Göttingen: Hogrefe; 1983.
23. Merk M. Entwicklung und Implementierung PC-gestützter akustischer Analyseverfahren für die klinische Diagnostik neurogener Sprechstörungen. Dissertation, Universität der Bundeswehr München; 2002.
24. Merk M, Ziegler W. MoDiaS - a PC-based system for routine acoustic speech analysis of neurogenic speech disorders. In: Maasen B, Groenen P, editors. Pathologies of speech and language advances in clinical phonetics and linguistics. London: Whurr; 1999. p. 315-21.
25. Weintraub S, Mesulam MM. Mental state assessment of young and elderly adults in behavioral neurology. Philadelphia: Davis; 1985.
26. Karnath HO. Deficits of attention in acute and recovered visual hemi-neglect. Neuropsychologia. 1988;26:27-43.
27. Ravizza SM, McCormick CA, Schlerf JE, Justus T, Ivry RB, Fiez JA. Cerebellar damage produces selective deficits in verbal working memory. Brain. 2006;129(Pt 2):306-20. (Pubitemid 43164356)
28. Timmann D, Daum I. How consistent are cognitive impairments in patients with cerebellar disorders? Invited review. Behav Neurol. in press.
29. Ackermann H, Hertrich I, Ziegler W, Bitzer M, Bien S. Acquired dysfluencies following infarction of the left mesiofrontal cortex. Aphasiology. 1996;10:409-17.
30. Marien P, Saerens J, Nanhoe R, Moens E, Nagels G, Pickut BA, et al. Cerebellar induced aphasia: case report of cerebellar induced prefrontal aphasic language phenomena supported by SPECT findings. J Neurol Sci. 1996;144(1-2):34-43. (Pubitemid 27019156)
31. Zettin M, Cappa SF, D'Amico A, Rago R, Perino C, Perani D, et al. Agrammatic speech production after a right cerebellar haemorrhage. Neurocase. 1997;3:375-80. (Pubitemid 27507628)
32. Fabbro F, Tavano A, Corti S, Bresolin N, De Fabritiis P, Borgatti R. Long-term neuropsychological deficits after cerebellar infarctions in two young adult twins. Neuropsychologia. 2004;42(4):536-45. (Pubitemid 38064302)
33. Kalashnikova LA, Zueva YV, Pugacheva OV, Korsakova NK. Cognitive impairments in cerebellar infarcts. Neurosci Behav Physiol. 2005;35(8):773-9. (Pubitemid 41300502)
34. Riva D, Giorgi C. The cerebellum contributes to higher functions during development. Evidence from a series of children surgically treated for posterior fossa tumours. Brain. 2000;123:1051-61.
35. Ackermann H, Mathiak K, Riecker A. The contribution of the cerebellum to speech production and speech perception: clinical and functional imaging data. Cerebellum. 2007;6(3):202-13. (Pubitemid 47360068)
36. Gomez Beldarrain M, Garcia-Monco JC, Quintana JM, Llorens V, Rodeno E. Diaschisis and neuropsychological performance after cerebellar stroke. Eur Neurol. 1997;37(2):82-9. (Pubitemid 27077807)
37. Catsman-Berrevoets CE, Van Dongen HR, Mulder PG, Paz y Geuze D, Paquier PF, Lequin MH. Tumour type and size are high risk factors for the syndrome of "cerebellar" mutism and subsequent dysarthria. J Neurol Neurosurg Psychiatry. 1999;67(6):755-7.
38. Baier B, Karnath HO, Thömke F, Birklein F, Müller N, Dieterich M. Is there a link between spatial neglect and vestibular function at the cerebellar level? J Neurol. 2010; Apr 22.
39. Silveri MC, Misciagna S, Terrezza G. Right side neglect in right cerebellar lesion. J Neurol Neurosurg Psychiatry. 2001;71:114-7.
40. Kim EJ, Choi KD, Han MK, Lee BH, Seo SW, Moon SY, et al. Hemispatial neglect in cerebellar stroke. J Neurol Sci. 2008;275(1-2):133-8.