Difference in the effects of tandospirone on ataxia in various types of spinocerebellar degeneration: An open-label study

Cerebellum

Volumn 9, Issue 4, 2010, Pages 567-570

  Takei, Asako ^a   Hamada, Shinsuke ^a   Homma, Sanae ^a   Hamada, Keiko ^a   Tashiro, Kunio ^a   Hamada, Takeshi ^a  

^a Hokuyukai Neurology Hospital   (Japan)

Author keywords

5 HT1A agonist; Ataxia; Spinocerebellar degeneration; Tandospirone; Therapy

Indexed keywords

TANDOSPIRONE;

ABSENCE OF SIDE EFFECTS; ADULT; AGED; ARTICLE; CEREBELLAR ATAXIA; CLINICAL ARTICLE; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DEPRESSION; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; HUMAN; INTERNATIONAL COOPERATION; MACHADO JOSEPH DISEASE; OUTCOME ASSESSMENT; PARKINSONISM; PATIENT ASSESSMENT; PRIORITY JOURNAL; PSYCHOLOGICAL RATING SCALE; SCORING SYSTEM; SELF REPORT; SHY DRAGER SYNDROME; SPINOCEREBELLAR DEGENERATION;

ADULT; AGED; ATAXIA; DEPRESSION; FEMALE; HUMANS; ISOINDOLES; MALE; MIDDLE AGED; PIPERAZINES; PYRIMIDINES; SEROTONIN RECEPTOR AGONISTS; SPINOCEREBELLAR DEGENERATIONS;

EID: 79952736047     PISSN: 14734222     EISSN: 14734230     Source Type: Journal    
DOI: 10.1007/s12311-010-0199-0     Document Type: Article

References (18)

1. Trouillas P, Brudon F, Adeleine P. Improvement of cerebellar ataxia with levorotatory form of 5-hydroxytryptophan. A doubleblind study with quantified data processing. Arch Neurol. 1988;45:1217-22.
2. Lou JS, Goldfarb L, McShane L, et al. Use of buspirone for treatment of cerebellar ataxia. An open-label study. Arch Neurol. 1995;52:982-8.
3. Takei A, Honma S, Kawashima A, et al. Beneficial effects of tandospirone on ataxia of a patient with Machado - Joseph disease. Psychiatry Clin Neurosci. 2002;56:181-5. (Pubitemid 34266621)
4. Takei A, Fukazawa T, Hamada T, et al. Effects of tandospirone on "5-HT1A receptor - associated symptoms" in patients with Machado - Joseph disease. An open-label study. Clin Neuropharmacol. 2004;27:9-13.
5. Trouillas P. L-5-Hydroxytryptophan treatment in cerebellar ataxia: clinical and etiological correlations.Mov Disord. 1990;5(supplement 1):6.
6. Monte TL, Rieder CR, Tort AB, et al. Use of fluoxetine for treatment of Machado - Joseph disease: an open-label study. Acta Neurol Scand. 2003;107:207-10. (Pubitemid 36398996)
7. Brice A, Pulst SM. Spinocerebellar degenerations: the ataxias and spastic paraplegias. Philadelphia: Butterworth Heinemann Elsevier; 2007.
8. Takei A, Hamada T, Yabe I, et al. Treatment of cerebellar ataxia with 5-HT1A agonist. Cerebellum. 2005;4:211-5. (Pubitemid 41354431)
9. Assadi M, Campellone JV, Janson CG, et al. Treatment of spinocerebellar ataxia with buspirone. J Neurol Sci. 2007;260:143-6. (Pubitemid 47212219)
10. Gilman S, Low PA, Quinn N, et al. Consensus statement on the diagnosis of multiple system atrophy. J Neurol Sci. 1999;63:94-8. (Pubitemid 29155424)
11. Trouillas P, Takayanagi T, Hallett M, et al. International cooperative ataxia rating scale for pharmacological assessment of the cerebellar syndrome. The ataxia Neuropharmacology Committee of the World Federation of Neurology. J Neurol Sci. 1997;145:205-11. (Pubitemid 27121687)
12. Wisden W, Murray AJ, McClure C, Wulff P. Studying cerebellar circuits by remote control of selected neuronal types with GABA receptors. Front Mol Neurosci. 2009;11:2-29.
13. Maura G, Roccatagliata E, Ulivi M, et al. Serotonin-glutamate interaction in rat cerebellum: involvement of 5-HT1 and 5-HT2 receptors. Eur J Pharmacol. 1988;145:31-8. (Pubitemid 18018842)
14. Maura G, Raiteri M. Serotonin 5-HT1D and 5-HT1A receptors respectively mediate inhibition of glutamate release and inhibition of cyclic GMP production in rat cerebellum in vitro. J Neurochem. 1996;66:203-9.
15. Takiyama Y, Oyanagi S, Kawashima S, et al. A clinical and pathologic study of a large Japanese family with Machado - Joseph disease tightly linked to the DNA markers on chromosome 14q. Neurology. 1994;44:1302-8.
16. Ishikawa K, Watanabe M, Yoshizawa K, et al. Clinical, Neuropathological, and molecular study in two families with spinocerebellar ataxia type 6 (SCA6). J Neurol Neurosurg Psychiatry. 1999;67:86-9. (Pubitemid 29278333)
17. Abe K. Spinocerebellar degeneration. Tokyo: Shinkoh Igaku Shuppan; 1999 (in Japanese).
18. Koyano S, Iwabuchi K. Correlation of clinicopathological features and CAG repeats in SCA2. Nippon Rinsho. 1999;57:805-10.