Fatal hepatotoxicity in an elderly patient receiving low-dose quetiapine

American Journal of Psychiatry

Volumn 168, Issue 2, 2011, Pages 212-213

  Naharci, Mehmet Ilkin ^a   Karadurmus, Nuri ^a   Demir, Orhan ^a   Bozoglu, Ergun ^a   Ak, Mehmet ^a   Doruk, Huseyin ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALKALINE PHOSPHATASE; AMINOTRANSFERASE; BILIRUBIN; GAMMA GLUTAMYLTRANSFERASE; QUETIAPINE;

AGED; AGITATION; ALKALINE PHOSPHATASE BLOOD LEVEL; AMINOTRANSFERASE BLOOD LEVEL; APPETITE DISORDER; BILIRUBIN BLOOD LEVEL; CASE REPORT; CLINICAL FEATURE; DISEASE DURATION; FATIGUE; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; INSOMNIA; LETTER; LIVER FAILURE; LIVER TOXICITY; LOW DRUG DOSE; PRIORITY JOURNAL; TREATMENT DURATION; VOMITING;

AGED; ANTIPSYCHOTIC AGENTS; DIBENZOTHIAZEPINES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; FATAL OUTCOME; FEMALE; HUMANS; LIVER FAILURE; LIVER FUNCTION TESTS; MULTIPLE ORGAN FAILURE; PSYCHOMOTOR AGITATION; SLEEP INITIATION AND MAINTENANCE DISORDERS;

EID: 79952721104     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2010.10091292     Document Type: Letter

References (3)

1. Naranjo CA, Busto U, Sellers EM, Sandor P, Ruiz I, Roberts EA, Janecek E, Domecq C, Greenblatt DJ: A method for estimating the probability of adverse drug reactions. Clin Pharmacol Ther 1981; 30:239-2452
2. El Hajj I, Sharara AI, Rockey DC: Subfulminant liver failure associated with quetiapine. Eur J Gastroenterol Hepatol 2004; 16:1415-1418 (Pubitemid 39627546)
3. Shpaner A, Li W, Ankoma-Sey V, Botero RC: Drug-induced liver injury: hepatotoxicity of quetiapine revisited. Eur J Gastroenterol Hepatol 2008; 20:1106-1109