Epigenetically reprogramming of human embryonic stem cells by 3-deazaneplanocin a and sodium butyrate

International Journal of Preventive Medicine

Volumn 2, Issue 2, 2011, Pages 73-78

  Azghadi, Soheila ^a   Clark, Amander T ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Infertility; Modeling; Reprogramming; Stemcell

Indexed keywords

3 DEAZANEPLANOCIN A; BUTYRIC ACID; LYSINE;

ANIMAL CELL; ARTICLE; CELL LOSS; CELL RENEWAL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EMBRYO; EMBRYONIC STEM CELL; EPIGENETICS; EVIDENCE BASED MEDICINE; FEMALE; GENE EXPRESSION REGULATION; GENETIC MARKER; HISTONE METHYLATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; MALE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PLURIPOTENT STEM CELL; PRIMORDIAL GERM CELL; PROCESS OPTIMIZATION; UPREGULATION; WESTERN BLOTTING; X CHROMOSOME INACTIVATION;

EID: 79952715207     PISSN: 20087802     EISSN: 20088213     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Ware CB, Wang L, Mecham BH, Shen L, Nelson AM, Bar M, et al. Histone deacetylase inhibition elicits an evolutionarily conserved self-renewal program in embryonic stem cells. Cell Stem Cell 2009; 4(4): 359-69.
2. Sugimoto M, Abe K. X chromosome reactivation initiates in nascent primordial germ cells in mice. PLoS Genet 2007; 3(7): e116.
3. Silva SS, Rowntree RK, Mekhoubad S, Lee JT. Xchromosome inactivation and epigenetic fluidity in human embryonic stem cells. Proc Natl Acad Sci U S A 2008; 105(12): 4820-5.
4. Martens JH, O'Sullivan RJ, Braunschweig U, Opravil S, Radolf M, Steinlein P, et al. The profile of repeat-associated histone lysine methylation states in the mouse epigenome. EMBO J 2005; 24(4): 800-12.
5. Miranda TB, Cortez CC, Yoo CB, Liang G, Abe M, Kelly TK, et al. DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation. Mol Cancer Ther 2009; 8(6): 1579-88.