Cowden syndrome and reconstructive breast surgery: Case reports and review of the literature

Journal of Plastic, Reconstructive and Aesthetic Surgery

Volumn 64, Issue 4, 2011, Pages 545-549

  Ali, E ^a   Athanasopoulos, P G ^a   Forouhi, P ^a   Malata, C M ^a  

^a ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Cowden syndrome; Expandable implants; Immediate breast reconstruction; Phosphatase and tensin homologue on chromosome ten (PTEN); Prophylactic mastectomy

Indexed keywords

PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE;

ARTICLE; BREAST CANCER; BREAST RECONSTRUCTION; CASE REPORT; COWDEN SYNDROME; GENE MUTATION; HUMAN; MASTECTOMY; MEDICAL LITERATURE; NIPPLE; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; RISK MANAGEMENT; RISK REDUCTION; SURGICAL TECHNIQUE;

ADULT; BREAST NEOPLASMS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAMARTOMA SYNDROME, MULTIPLE; HUMANS; MAMMAPLASTY; MASTECTOMY; MIDDLE AGED; MUTATION; PTEN PHOSPHOHYDROLASE; RISK REDUCTION BEHAVIOR;

EID: 79952704809     PISSN: 17486815     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bjps.2010.04.047     Document Type: Article

References (16)

1. Morgensztern D, McLeod HL. PI3K/Akt/mTOR pathway as a target for cancer therapy. Anticancer Drugs 2005;16:797-803 [Review].
2. Uppal S, Mistry D, Coatesworth AP. Cowden disease: a review. Int J Clin Pract 2007;61:645-52. (Pubitemid 46449842)
3. Nelen MR, Kremer H, Konings IB, et al. Novel PTEN mutations in patients with Cowden disease: absence of clear genotypephenotype correlations. Eur J Hum Genet 1999;7:267-73. (Pubitemid 29213732)
4. Eng C. PTEN: one gene, many syndromes. Hum Mutat 2003;22:183-98. (Pubitemid 37071635)
5. Pilarski R. Cowden syndrome: a critical review of the clinical literature. J Genet Couns 2009;18:13-27.
6. Nusbaum R, Vogel KJ, Ready K. Susceptibility to breast cancer: hereditary syndromes and low penetrance genes. Breast Dis 2006;27:21-50.
7. Schrager CA, Schneider D, Gruener AC, et al. Clinical and pathological features of breast disease in Cowden's syndrome: an underrecognized syndrome with an increased risk of breast cancer. Hum Pathol 1998;29:47-53. (Pubitemid 28049545)
8. Batista LI, Lu KH, Beahm EK, et al. Coordinated prophylactic surgical management for women with hereditary breastovarian cancer syndrome. BMC Cancer 2008;8:101.
9. Hodgson EL, Malata CM. Implant-based breast reconstruction following mastectomy. Breast Dis 2002;16:47-63. (Pubitemid 37038312)
10. Spear SL, Spittler CJ. Breast reconstruction with implants and expanders. Plast Reconstr Surg 2001;107:177-87. quiz 188.
11. Hsieh F, Shah A, Malata CM. Experience with the Mentor Contour Profile Becker-35 expandable implants in reconstructive breast surgery. J Plast Reconstr Aesthet Surg; 2009 Jun 27.
12. Cicchetti S, Leone MS, Franchelli S, et al. One-stage breast reconstruction using McGhan Style 150 biodimensional expanders: a review of 107 implants with six years experience. J Plast Reconstr Aesthet Surg 2006;59:1037-42. (Pubitemid 44391155)
13. Whitfield GA, Horan G, Irwin MS, et al. Incidence of severe capsular contracture following implant-based immediate breast reconstruction with or without postoperative chest wall radiotherapy using 40 Gray in 15 fractions. Radiother Oncol 2009;90:141-7.
14. Behranwala KA, Dua RS, Ross GM, et al. The influence of radiotherapy on capsule formation and aesthetic outcome after immediate breast reconstruction using biodimensional anatomical expander implants. J Plast Reconstr Aesthet Surg 2006;59:1043-51. (Pubitemid 44391162)
15. Spear SL, Pennanen M, Barter J, et al. Prophylactic mastectomy, oophorectomy, hysterectomy, and immediate transverse rectus abdominis muscle flap breast reconstruction in a BRCA-2 positive patient. Plast Reconstr Surg 1999;103:548-53. discussion 554-555.
16. Patani N, Devalia H, Anderson A, et al. Oncological safety and patient satisfaction with skin-sparing mastectomy and immediate breast reconstruction. Surg Oncol 2008;17:97-105 [Epub 2008 Feb 21].