Pharmacological blockade or genetic knockout of the NOP receptor potentiates the rewarding effect of morphine in rats

Drug and Alcohol Dependence

Volumn 114, Issue 2-3, 2011, Pages 253-256

  Rutten, Kris ^a   De Vry, Jean ^a   Bruckmann, Walter ^a   Tzschentke, Thomas M ^a  

^a GRÜNENTHAL GMBH   (Germany)

Author keywords

Addiction; Conditioned place preference; Drug abuse; Nociceptin; Opioids; ORL1 (receptor)

Indexed keywords

1 (1 CYCLOOCTYLMETHYL 3 HYDROXYMETHYL 4 PIPERIDYL) 3 ETHYL 1,3 DIHYDRO 2H BENZIMIDAZOL 2 ONE; MORPHINE; NOCICEPTIN RECEPTOR;

ANIMAL EXPERIMENT; ARTICLE; CONDITIONING; CONTROLLED STUDY; DRUG EFFECT; DRUG TARGETING; GENE INACTIVATION; MALE; NONHUMAN; PLACE PREFERENCE; PRIORITY JOURNAL; RAT; RECEPTOR BLOCKING; WILD TYPE;

ANIMALS; BENZIMIDAZOLES; CONDITIONING (PSYCHOLOGY); DRUG SYNERGISM; GENE KNOCKOUT TECHNIQUES; GENE TARGETING; MALE; MORPHINE; OPIOID PEPTIDES; PIPERIDINES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; REWARD;

RATTUS;

EID: 79952699059     PISSN: 03768716     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2010.10.004     Document Type: Article

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