Evaluation of real-time polymerase chain reaction, interferon-gamma, adenosine deaminase, and immunoglobulin A for the efficient diagnosis of pleural tuberculosis

International Journal of Infectious Diseases

Volumn 15, Issue 4, 2011, Pages

  Kalantri, Yatiraj ^a   Hemvani, Nanda ^a   Chitnis, D S ^a  

^a CHOITHRAM HOSPITAL AND RESEARCH CENTRE   (India)

Author keywords

Adenosine deaminase; Immunoglobulin A; Interferon gamma; Pleural tuberculosis; Polymerase chain reaction; Tuberculosis

Indexed keywords

ADENOSINE DEAMINASE; GAMMA INTERFERON; IMMUNOGLOBULIN A; RNA 16S;

ADULT; ARTICLE; COLORIMETRY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE SEQUENCE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MYCOBACTERIUM TUBERCULOSIS; PLEURA BIOPSY; PLEURA EFFUSION; PLEURA FLUID; REAL TIME POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; TUBERCULOUS PLEURISY;

ADENOSINE DEAMINASE; ADULT; AREA UNDER CURVE; COLORIMETRY; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; IMMUNOGLOBULIN A; INTERFERON-GAMMA; MALE; MIDDLE AGED; PLEURAL EFFUSION; POLYMERASE CHAIN REACTION; PREDICTIVE VALUE OF TESTS; RNA, RIBOSOMAL, 16S; ROC CURVE; SENSITIVITY AND SPECIFICITY; TUBERCULOSIS, PLEURAL; YOUNG ADULT;

EID: 79952695625     PISSN: 12019712     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijid.2010.11.011     Document Type: Article

References (31)

1. Elzinga G., Raviglione M.C., Maher D. Scale up: meeting targets in global tuberculosis control. Lancet 2004, 363:814-819.
2. World Health Organization. TB epidemiology and surveillance workshop, 2006. Geneva: WHO; 2006. Available at: (accessed December 11, 2009). http://www.who.int/tb/surveillanceworkshop/trend_analysis/increasing_decreasing_over_under_diagnosis_of_extrapulmonary_tb.htm.
3. Kipp A.M., Stout J.E., Hamilton C.D., Rie A.V. Extrapulmonary tuberculosis, human immunodeficiency virus, and foreign birth in North Carolina, 1993-2006. BMC Public Health 2008, 8:107.
4. Sharma S.K., Mohan A. Extrapulmonary tuberculosis. Indian J Med Res 2004, 120:316-353.
5. Frye M.D., Pozsik C.J., Sahn S.A. Tuberculous pleurisy is more common in AIDS than in non-AIDS patients with tuberculosis. Chest 1997, 112:393-397.
6. Baumann M.H., Nolan R., Petrini M., Lee Y.C., Light R.W., Schneider E. Pleural tuberculosis in the United states: incidence and drug resistance. Chest 2007, 131:1125-1132.
7. Light R.W. Useful test on the pleural fluid in the management of patients with pleural effusions. Curr Opin Pulm Med 1999, 5:245-249.
8. Trajman A., Pai M., Dheda K., van Zyl Smit R., Zwerling A.A., Joshi R., et al. Novel tests for diagnosing tuberculous pleural effusion: what works and what does not?. Eur Respir J 2008, 31:1098-1106.
9. Aoe K., Hikari A., Murakami T., Eda R., Maeda T., Sugi K., et al. Diagnostic significance of interferon-γ in tuberculous pleural effusions. Chest 2003, 123:740-744.
10. Jiang J., Shi H.Z., Liang Q.L., Qin S.M., Qin X.J. Diagnostic value of interferon-γ in tuberculous pleurisy: a meta-analysis. Chest 2007, 131:1133-1141.
11. Greco S., Girardi E., Masciangelo R., Capoccetta G.B., Saltini C. Adenosine deaminase and interferon-γ measurements for the diagnosis of tuberculous pleurisy: a meta-analysis. Int J Tuberc Lung Dis 2003, 7:777-786.
12. Villegas M.V., Labrada L.A., Saravia N.G. Evaluation of polymerase chain reaction, adenosine deaminase, and interferon-γ in pleural fluid for the differential diagnosis of pleural tuberculosis. Chest 2000, 118:1335-1364.
13. Trajman A., Kaisermann C., Luiz R.R., Sperhacke R.D., Rossetti M.L., Feres S.M., et al. Pleural fluid ADA, IgA-ELISA, and PCR sensitivities for the diagnosis of pleural tuberculosis. Scand J Lab Clin Invest 2007, 67:877-884.
14. Perez-Rodriguez E., Perez Walton I.J., Sanchez Hernandez J.J., Pallares E., Rubi J., Jimenez Castro D., et al. ADA1/ADAp ratio in pleural tuberculosis: an excellent diagnostic parameter in pleural fluid. Respir Med 1999, 93:816-821.
15. Gorguner M., Cerci M., Gorguner I. Determination of adenosine deaminase activity and its isoenzymes for diagnosis of pleural effusions. Respirology 2000, 5:321-324.
16. Pai M., Flores L.L., Hubbard A., Riley L.W., Colford L.M. Nucleic acid amplification tests in the diagnosis of tuberculous pleuritis: a systematic review and meta-analysis. BMC Infect Dis 2004, 4:6.
17. Baba K., Pathak S., Sviland L., Langeland N., Hoosen A.A., Asjo B., et al. Real-time quantitative PCR in the diagnosis of tuberculosis in formalin-fixed paraffin-embedded pleural tissue in patients from a high HIV endemic area. Diagn Mol Pathol 2008, 17:112-117.
18. Moon J.W., Chang Y.S., Kim S.K., Kim Y.S., Lee H.M., Kim S.K., et al. The clinical utility of polymerase chain reaction for the diagnosis of pleural tuberculosis. Clin Infect Dis 2005, 41:660-666.
19. Lima D.M., Colares J.K., da Fonseca B.A. Combined use of the polymerase chain reaction and detection of adenosine deaminase activity on pleural fluid improves the rate of diagnosis of pleural tuberculosis. Chest 2003, 124:909-914.
20. Kaisermann M.C., Sardella I.G., Trajman A., Coelho L.V., Kampfer S., Jonas F., et al. IgA antibody responses to Mycobacterium tuberculosis recombinant MPT-64 and MT-10.3 (Rv3019c) antigens in pleural fluid of patients with tuberculous pleurisy. Int J Tuberc Lung Dis 2005, 9:461-466.
21. Light R.W., MacGregor M.I., Luchsinger P.C., Ball W.C. Pleural effusions: the diagnostic separation of transudates and exudates. Ann Intern Med 1972, 77:507-513.
22. Giusti G., Galanti B. Adenosine deaminase: colorimetric method. Methods of enzymatic analysis 1984, 315-323. Verlag Chemie, Weinheim, Germany. H.U. Bergmeyer (Ed.).
23. Alifano M., Sofia M., Mormile M., Micco A., Mormile A.F., Del Pezzo M., et al. IgA immune response against the mycobacterial antigen A-60 in patients with active pulmonary tuberculosis. Respiration 1996, 63:292-297.
24. Metz C.E. Basic principles of ROC analysis. Semin Nucl Med 1978, 8:283-298.
25. Liam C.K., Lim K.H., Wong C.M. Causes of pleural exudates in a region with a high incidence of tuberculosis. Respirology 2000, 5:33-38.
26. Valdes L., Pose A., San Joes E., Martinez Vazquez J.M. Tuberculous pleural effusions. Eur J Intern Med 2003, 14:77-88.
27. Hillemann D., Galle J., Vollmer E., Richter E. Real time PCR assay for improved detection of Mycobacterium tuberculosis complex in paraffin-embedded tissues. Int J Tuberc Lung Dis 2006, 10:340-342.
28. Kraus G., Cleary T., Miller N., Seivright R., Young A.K., Spruill G., et al. Rapid and specific detection of Mycobacterium tuberculosis complex using fluorogenic probes and real-time PCR. Mol Cell Probes 2001, 15:375-383.
29. Ghanei M., Aslani A., Bahrami H., Adhami H. Simple method for rapid diagnosis of tuberculosis pleuritis: a statistical approach. Asian Cardiovasc Thorac Ann 2004, 12:23-29.
30. Neves D.D., Dias R.M., Cunha A.J. Predictive model for the diagnosis of tuberculous pleural effusion. Braz J Infect Dis 2007, 11:83-88.
31. Dheda K., van Zyl-Smit R.N., Sechi L.A., Badri M., Meldau R., Meldau S., et al. Utility of quantitative T-cell responses versus unstimulated interferon-gamma for the diagnosis of pleural tuberculosis. Eur Respir J 2009, 34:1118-1126.