Trends in mupirocin resistance in meticillin-resistant Staphylococcus aureus and mupirocin consumption at a tertiary care hospital

Journal of Hospital Infection

Volumn 77, Issue 4, 2011, Pages 360-362

  Lee, A S ^a   Macedo Vinas, M ^a   Francois P ^a   Renzi, G ^a   Vernaz, N ^a   Schrenzel, J ^a   Pittet, D ^a   Harbarth, S ^a  

^a GENEVA UNIVERSITY HOSPITALS   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID TRANSFER RNA LIGASE; BACTERIAL ENZYME; PSEUDOMONIC ACID;

ANTIBIOTIC RESISTANCE; BACTERIAL GENE; BACTERIAL MUTATION; BLOOD CULTURE; CORRELATION ANALYSIS; DRUG MECHANISM; DRUG USE; HUMAN; LETTER; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MINIMUM INHIBITORY CONCENTRATION; MUPA GENE; NONHUMAN; POINT MUTATION; STAPHYLOCOCCUS INFECTION; TERTIARY HEALTH CARE; TREND STUDY;

ANTI-BACTERIAL AGENTS; CARRIER STATE; DRUG RESISTANCE, BACTERIAL; DRUG UTILIZATION; HOSPITALS; HUMANS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; MUPIROCIN; STAPHYLOCOCCAL INFECTIONS;

EID: 79952695185     PISSN: 01956701     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhin.2010.11.002     Document Type: Letter

References (8)

1. Thomas C.M., Hothersall J., Willis C.L., Simpson T.J. Resistance to and synthesis of the antibiotic mupirocin. Nat Rev Microbiol 2010, 8:281-289.
2. de Oliveira N.E., Cardozo A.P., Marques Ede A., dos Santos K.R., Giambiagi-deMarval M. Interpretive criteria to differentiate low- and high-level mupirocin resistance in Staphylococcus aureus. J Med Microbiol 2007, 56:937-939.
3. Patel J.B., Gorwitz R.J., Jernigan J.A. Mupirocin resistance. Clin Infect Dis 2009, 49:935-941.
4. Vivoni A.M., Santos K.R., de-Oliveira M.P., et al. Mupirocin for controlling methicillin-resistant Staphylococcus aureus: lessons from a decade of use at a university hospital. Infect Control Hosp Epidemiol 2005, 26:662-667.
5. Jones J.C., Rogers T.J., Brookmeyer P., et al. Mupirocin resistance in patients colonized with methicillin-resistant Staphylococcus aureus in a surgical intensive care unit. Clin Infect Dis 2007, 45:541-547.
6. Antonio M., McFerran N., Pallen M.J. Mutations affecting the Rossman fold of isoleucyl-tRNA synthetase are correlated with low-level mupirocin resistance in Staphylococcus aureus. Antimicrob Agents Chemother 2002, 46:438-442.
7. Finlay J.E., Miller L.A., Poupard J.A. Interpretive criteria for testing susceptibility of staphylococci to mupirocin. Antimicrob Agents Chemother 1997, 41:1137-1139.
8. Lee AS, Macedo M, François P, et al. Impact of combined low-level mupirocin and chlorhexidine resistance on persistent methicillin-resistant Staphylococcus aureus carriage after decolonization therapy: a case-control study. Proceedings of the 50th Interscience Conference on Antimicrobial Agents and Chemotherapy, 12-15 September 2010, Boston, USA.