A case history of multimodal therapy in healing a complicated diabetic foot wound: Negative pressure, dermal replacement and pulsed radio frequency energy therapies

International Wound Journal

Volumn 8, Issue 2, 2011, Pages 132-139

  Frykberg, Robert ^a   Martin, Erin ^a   Tallis, Arthur ^a   Tierney, Edward ^a  

^a CARL T HAYDEN VA MEDICAL CENTER   (United States)

Author keywords

Complex wound; Diabetic foot; Multimodal therapies

Indexed keywords

METRONIDAZOLE; PIPERACILLIN PLUS TAZOBACTAM; VANCOMYCIN;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; CASE REPORT; CASE STUDY; CELLULITIS; CHILL; DEBRIDEMENT; DERMAL REPLACEMENT THERAPY; DIABETIC FOOT; DIABETIC PATIENT; FASCIOTOMY; FEVER; FOOT AMPUTATION; HALLUX; HUMAN; HUMAN TISSUE; KIDNEY DYSFUNCTION; LEG LENGTHENING; MALAISE; MALE; MEDICAL HISTORY; NAUSEA; NON INSULIN DEPENDENT DIABETES MELLITUS; OSTEOMYELITIS; PERIPHERAL OCCLUSIVE ARTERY DISEASE; PLANTAR ULCER; PRIORITY JOURNAL; PULSED RADIOFREQUENCY ENERGY THERAPY; SKIN GRAFT; SKIN NECROSIS; TENDO ACHILLES LENGTHENING; TISSUE NECROSIS; TOE GANGRENE; TRANSMETATARSAL AMPUTATION; VACUUM ASSISTED CLOSURE; WOUND CARE; WOUND HEALING;

CATHETER ABLATION; DEBRIDEMENT; DERMIS; DIABETIC FOOT; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; NEGATIVE-PRESSURE WOUND THERAPY; WOUND HEALING;

EID: 79952691521     PISSN: 17424801     EISSN: 1742481X     Source Type: Journal    
DOI: 10.1111/j.1742-481X.2010.00759.x     Document Type: Article

References (26)

1. Dworkin MS, Westercamp MD, Park L, McIntyre A. The epidemiology of necrotizing fasciitis including factors associated with death and amputation. Epidemiol Infect 2009;137:1609-14.
2. Lipsky BA, Berendt AR, Deery HG, Embil JM, Joseph WS, Karchmer AW, LeFrock JL, Lew DP, Mader JT, Norden C, Tan JS. Infectious Diseases Society of America Diagnosis and treatment of diabetic foot infections. Plast Reconstr Surg 2006;117(7 Suppl):212S-38S.
3. Zgonis T, Stapleton JJ, Girard-Powell VA, Hagino RT. Surgical management of diabetic foot infections and amputations. AORN J 2008;87:935-46; quiz 947-50.
4. Liu Y, Chi C, Ho M, Chen C. Microbiology and factors affecting mortality in necrotizing fasciits. J Microbiol Immunol Infect 2005;38:430-5.
5. Jain A, Varma A, Mangalanandan Kumar PH, Bal A. Surgical outcome of necrotizing fasciitis in diabetic lower limbs. J Diabetic Foot Comp 2009;1:80-84
6. Bahebeck J, Sobgui E, Loic F, Nonga BN, Mbanya JC, Sosso M. Limb-threatening and life-threatening diabetic extremities: clinical patterns and outcomes in 56 patients. J Foot Ankle Surg 2010;49:43-6.
7. Wang K-C, Shih CH. Necrotizing fasciitis of the extremities. J Trauma 1992;32:259-64.
8. Voros D, Pissiotis C, Georgantas D, Katsaragakis S, Antoniou S, Papadimitriou J. Role of early and aggressive surgery in the treatment of severe necrotizing soft tissue infections. Br J Surg 1993;80:1190-1.
9. Sheehan P, Jones P, Caselli A, Giurini JM, Veves A. Percent change in wound area of diabetic foot ulcers over a 4-week period is a robust predictor of complete healing in a 12-week prospective trial. Diabetes Care 2003;26:1879-82.
10. Snyder R, Kirsner R, Warriner R, Lavery LA, Hanft J, Sheehan P. Consensus recommendations on advancing the standard of care for treating neuropathic foot ulcers in patients with diabetes. Ostomy Wound Manage 2010; 56(Suppl 4):S1-S24.
11. Marston WA. Dermagraft, a bioengineered human dermal equivalent for the treatment of chronic nonhealing diabetic foot ulcer. Expert Rev Med Devices 2004;1:21-31.
12. Sumio B, Driver V, Gibbons G, Hollowat G, Joseph W, Lavery L, McGuigan F, Steinberg J, Andersen C, Blume P, Attinger C. A multidisciplinary approach to limb preservation: the role of V.A.C. therapy. Wounds 2009; (Suppl):1-20.
13. Orgill DP, Manders EK, Sumpio BE, Lee RC, Attinger CE, Gurtner GC, Ehrlich HP. The mechanics of action of vacum assisted closure: more to learn. Surgery 2009;146:40-51.
14. Bollero D, Driver V, Glat P, Gupta S, Lázaro-Martínez JL, Lyder C, Ottonello M, Pelham F, Vig S, Woo K. Ostomy Wound Management 2010;56(5 Suppl):1-18.
15. Frykberg RG, Zgonis T, Armstrong DG, Driver VR, Giurini J, Kravitz S, Landsman AS, Lavery LA, Moore JC, Schuberth JM, Wukich DK, Andersen C, Vanore J. Diabetic foot disorders: a clinical practice guideline (2006 revision). J Foot Ankle Surg 2006;45(Suppl 5):S2-S66.
16. Andros G, Armstrong DG, Attinger C, Boulton AJM, Frykberg RG, Joseph W, Lavery LA, Morbach S, Niezgoda JA, Toursarkissian B. Consensus statement on negative pressure wound therapy (V.A.C. therapy) for the management of diabetic foot wounds. Ostomy Wound Manage 2006; 52(6 Suppl):1-32.
17. Naughton G, Mansbridge J, Gentskow G. A metabolically active human dermal replacement for the treatment of diabetic foot ulcers. Artif Organs 21:1203-10.
18. Negative Pressure Wound Therapy (NPWT) systems - Preliminary Public Health Notification. [accessed 10 March 2010].
19. George FR, Lukas RJ, Moffett J, Ritz MC. In-vitro mechanisms of cell proliferation induction: a novel bioactive treatment for accelerated wound healing. Wounds 2002;14:107-15.
20. Larsen JA, Overstreet J. Pulsed radio frequency energy in the treatment of complex diabetic foot wounds: two cases. J Wound Ostomy Continence Nurs 2008;35:523-7.
21. Frykberg R, Tierney E, Tallis A, Klotzbach T. Cell proliferation induction: healing chronic wounds through low-energy pulsed radiofrequency. Int J Low Extrem Wounds 2009;8:45-51.
22. Cleary SF, Liu LM, Merchant RE. In vitro lymphocyte proliferation induced by radio-frequency electromagnetic radiation under isothermal conditions. Bioelectromagnetics 1990;11:47-56.
23. Gilbert TL, Griffin N, Moffett J, Ritz MC, George FR. The Provant Wound Closure System induces activation of p44/42 MAP kinase in normal cultured human fibroblasts. Ann N Y Acad Sci 2002;961:168-71.
24. Moffett JGN, Ritz M, George F. The effects of a pulsed radio frequency electromagnetic field on selected genes. Symposium on Advances in Wound Care. San Diego, CA, 2008.
25. Moffett JGN, Ritz M, George F. Increased gene expression in cultured human dermal fibroblasts in response to a pulsed radio frequency electromagnetic field and implications in chronic wound healing. Symposium on Advances in Wound Care, San Diego, CA, 2008.
26. Younger AS, Awwad MA, Kalla TP, de Vries G. Risk factors for failure of transmetatarsal amputation in diabetic patients: a cohort study. Foot Ankle Int 2009;30:1177-82.